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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleAdult Brain
Open Access

Interobserver Reliability on Intravoxel Incoherent Motion Imaging in Patients with Acute Ischemic Stroke

K. Yamashita, R. Kamei, H. Sugimori, T. Kuwashiro, S. Tokunaga, K. Kawamata, K. Furuya, S. Harada, J. Maehara, Y. Okada and T. Noguchi
American Journal of Neuroradiology April 2022, DOI: https://doi.org/10.3174/ajnr.A7486
K. Yamashita
aFrom the Departments of Radiology (K.Y., R.K., K.F., S.H., J.M., T.N.)
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  • ORCID record for K. Yamashita
R. Kamei
aFrom the Departments of Radiology (K.Y., R.K., K.F., S.H., J.M., T.N.)
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H. Sugimori
bCerebrovascular Medicine and Neurology (H.S., T.K., Y.O.)
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T. Kuwashiro
bCerebrovascular Medicine and Neurology (H.S., T.K., Y.O.)
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S. Tokunaga
cNeuroendovascular Therapy (S.T.)
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K. Kawamata
dClinical Research Institute, and Medical Technology (K.K.), Division of Radiology, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan
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K. Furuya
aFrom the Departments of Radiology (K.Y., R.K., K.F., S.H., J.M., T.N.)
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S. Harada
aFrom the Departments of Radiology (K.Y., R.K., K.F., S.H., J.M., T.N.)
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J. Maehara
aFrom the Departments of Radiology (K.Y., R.K., K.F., S.H., J.M., T.N.)
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Y. Okada
bCerebrovascular Medicine and Neurology (H.S., T.K., Y.O.)
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T. Noguchi
aFrom the Departments of Radiology (K.Y., R.K., K.F., S.H., J.M., T.N.)
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  • FIG 1.
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    FIG 1.

    Representative DWI with a b-value of 1000 s/mm2 (A), IVIM D (B), f (C), and D* (D) maps obtained using a 2-step algorithm. A 90-year-old woman with AIS. IVIM f and D* are expressed in units of percentage and ×10−3 mm2/s, respectively. Interobserver agreement is shown for IVIM f (κ = 0.854; P < .001) and D* (κ = 0.789; P < .001) using the 2-step algorithm, which indicated almost perfect and substantial agreement, respectively.

  • FIG 2.
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    FIG 2.

    A DWI with a b-value of 1000 s/mm2 (A), IVIM D (B), f (C), D* (D) maps, and MRA (E) of a 73-year-old man with AIS. MR imaging was performed 7 days after symptom onset. Nondecreased IVIM f and D* are identified on the f and D* maps. MR angiography represents spontaneous recanalization of the occluded left distal MCA (E; arrows). MRA performed 33 hours after symptom onset (F) is also shown as a reference.

  • FIG 3.
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    FIG 3.

    Plots of Dmean (A), fmean (B), and D*mean (C) on both the affected and contralateral unaffected sides. The Dmean and fmean values were lower on the affected side (mean Dmean = 0.45 [SD, 0.09] × 10−3 mm2/s; mean fmean = 3.22% [SD, 2.93%]) than on the contralateral unaffected side (mean Dmean = 0.76 [SD, 0.11] × 10−3 mm2/s, P < .0001; mean fmean = 5.55% [SD, 2.16%], P = .0010). No statistical difference in mean D*mean was evident between the affected side (22.6 [SD, 7.24] × 10−3 mm2/s) and the contralateral unaffected side (24.3 [SD, 4.94] × 10−3 mm2/s; P = .24).

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K. Yamashita, R. Kamei, H. Sugimori, T. Kuwashiro, S. Tokunaga, K. Kawamata, K. Furuya, S. Harada, J. Maehara, Y. Okada, T. Noguchi
Interobserver Reliability on Intravoxel Incoherent Motion Imaging in Patients with Acute Ischemic Stroke
American Journal of Neuroradiology Apr 2022, DOI: 10.3174/ajnr.A7486

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Interobserver Reliability on Intravoxel Incoherent Motion Imaging in Patients with Acute Ischemic Stroke
K. Yamashita, R. Kamei, H. Sugimori, T. Kuwashiro, S. Tokunaga, K. Kawamata, K. Furuya, S. Harada, J. Maehara, Y. Okada, T. Noguchi
American Journal of Neuroradiology Apr 2022, DOI: 10.3174/ajnr.A7486
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