Hemorrhagic Transformation Rates following Contrast Media Administration in Patients Hospitalized with Ischemic Stroke

References

1. 1.↵
   The top 10 causes of death; Fact sheets. 2018; https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death. Accessed May 24, 2020
2. 2.↵
   1. Benjamin EJ,
   2. Muntner P,
   3. Alonso A, et al

   ; American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2019 Update: a report from the American Heart Association. Circulation 2019;139:e56–528 doi:10.1161/CIR.0000000000000659 pmid:30700139

   CrossRefPubMed
3. 3.↵
   1. Powers WJ,
   2. Rabinstein AA,
   3. Ackerson T, et al

   ; American Heart Association Stroke Council. 2018 Guidelines for the Early Management of Patients with Acute Ischemic Stroke: A Guideline for Healthcare Professionals from the American Heart Association/American Stroke Association. Stroke 2018;49:e46–110 doi:10.1161/STR.0000000000000158 pmid:29367334

   Abstract/FREE Full Text
4. 4.↵
   1. Birenbaum D,
   2. Bancroft LW,
   3. Felsberg GJ

   . Imaging in acute stroke. West J Emerg Med 2011;12:67–76 pmid:21694755

   PubMed
5. 5.↵
   1. Aviv RI,
   2. d’Esterre CD,
   3. Murphy BD, et al

   . Hemorrhagic transformation of ischemic stroke: prediction with CT perfusion. Radiology 2009;250:867–77 doi:10.1148/radiol.2503080257 pmid:19244051

   CrossRefPubMedWeb of Science
6. 6.↵
   1. Hom J,
   2. Dankbaar JW,
   3. Soares BP, et al

   . Blood-brain barrier permeability assessed by perfusion CT predicts symptomatic hemorrhagic transformation and malignant edema in acute ischemic stroke. AJNR Am J Neuroradiol 2011;32:41–48 doi:10.3174/ajnr.A2244 pmid:20947643

   Abstract/FREE Full Text
7. 7.↵
   1. Lin K,
   2. Kazmi KS,
   3. Law M, et al

   . Measuring elevated microvascular permeability and predicting hemorrhagic transformation in acute ischemic stroke using first-pass dynamic perfusion CT imaging. AJNR Am J Neuroradiol 2007;28:1292–98 doi:10.3174/ajnr.A0539 pmid:17698530

   CrossRefPubMed
8. 8.↵
   1. Lummel N,
   2. Schulte-Altedorneburg G,
   3. Bernau C, et al

   . Hyperattenuated intracerebral lesions after mechanical recanalization in acute stroke. AJNR Am J Neuroradiol 2014;35:345–51 doi:10.3174/ajnr.A3656 pmid:23907245

   Abstract/FREE Full Text
9. 9.↵
   1. Suh CH,
   2. Jung SC,
   3. Cho SJ, et al

   . Perfusion CT for prediction of hemorrhagic transformation in acute ischemic stroke: a systematic review and meta-analysis. Eur Radiol 2019;29:4077–87 doi:10.1007/s00330-018-5936-7 pmid:30617485

   CrossRefPubMed
10. 10.↵
    1. Warach S,
    2. Latour LL

    . Evidence of reperfusion injury, exacerbated by thrombolytic therapy, in human focal brain ischemia using a novel imaging marker of early blood-brain barrier disruption. Stroke 2004;35:2659–61 doi:10.1161/01.STR.0000144051.32131.09 pmid:15472105

    Abstract/FREE Full Text
11. 11.↵
    1. Khatri P,
    2. Broderick JP,
    3. Khoury JC, et al

    ; IMS I and II Investigators. Microcatheter contrast injections during intra-arterial thrombolysis may increase intracranial hemorrhage risk. Stroke 2008;39:3283–87 doi:10.1161/STROKEAHA.108.522904 pmid:18772441

    Abstract/FREE Full Text
12. 12.↵
    IMS II Trial Investigators. The Interventional Management of Stroke (IMS) II study. Stroke 2007;38:2127–35 doi:10.1161/STROKEAHA.107.483131 pmid:17525387

    Abstract/FREE Full Text
13. 13.↵
    1. Kurosawa Y,
    2. Lu A,
    3. Khatri P, et al

    . Intra-arterial iodinated radiographic contrast material injection administration in a rat middle cerebral artery occlusion and reperfusion model: possible effects on intracerebral hemorrhage. Stroke 2010;41:1013–17 doi:10.1161/STROKEAHA.110.578245 pmid:20360541

    Abstract/FREE Full Text
14. 14.↵
    1. Zhang J,
    2. Yang Y,
    3. Sun H, et al

    . Hemorrhagic transformation after cerebral infarction: current concepts and challenges. Ann Transl Med 2014;2:81 doi:10.3978/j.issn.2305-5839.2014.08.08 pmid:25333056

    CrossRefPubMed
15. 15.↵
    1. Morales H,
    2. Lu A,
    3. Kurosawa Y, et al

    . Decreased infarct volume and intracranial hemorrhage associated with intra-arterial nonionic iso-osmolar contrast material in an MCA occlusion/reperfusion model. AJNR Am J Neuroradiol 2014;35:1885–91 doi:10.3174/ajnr.A3953 pmid:24812016

    Abstract/FREE Full Text
16. 16.↵
    1. Buschur M,
    2. Aspelin P

    . Contrast media: history and chemical properties. Interv Cardiol Clin 2014;3:333–39 doi:10.1016/j.iccl.2014.03.008 pmid:28582217

    CrossRefPubMed
17. 17.↵
    1. Tomsick TA,
    2. Foster LD,
    3. Liebeskind DS, et al

    ; IMS III Investigators. Outcome differences between intra-arterial iso- and low-osmolality iodinated radiographic contrast media in the Interventional Management of Stroke III trial. AJNR Am J Neuroradiol 2015;36:2074–81 doi:10.3174/ajnr.A4421 pmid:26228892

    Abstract/FREE Full Text
18. 18.↵
    1. Morales H,
    2. Lu A,
    3. Kurosawa Y, et al

    . Variable MR and pathologic patterns of hemorrhage after iodinated contrast infusion in MCA occlusion/reperfusion model. J Neurointer Surg 2017;9:1248–52 doi:10.1136/neurintsurg-2016-012777 pmid:27899518

    Abstract/FREE Full Text
19. 19.↵
    Premier Healthcare Database White Paper: Data That Informs and Performs. 2019; https://products.premierinc.com/downloads/PremierHealthcareDatabaseWhitepaper.pdf. Accessed January 21, 2022
20. 20.↵
    1. Elixhauser A,
    2. Steiner C,
    3. Harris DR, et al

    . Comorbidity measures for use with administrative data. Med Care 1998;36:8–27 doi:10.1097/00005650-199801000-00004 pmid:9431328

    CrossRefPubMedWeb of Science
21. 21.↵
    1. Belani P,
    2. Schefflein J,
    3. Kihira S, et al

    . COVID-19 is an independent risk factor for acute ischemic stroke. AJNR Am J Neuroradiol 2020;41:1361–64 doi:10.3174/ajnr.A6650 pmid:32586968

    Abstract/FREE Full Text
22. 22.↵
    1. Aspelin P,
    2. Aubry P,
    3. Fransson SG, et al

    ; Nephrotoxicity in High-Risk Patients Study of Iso-Osmolar and Low-Osmolar Non-Ionic Contrast Media Study Investigators. Nephrotoxic effects in high-risk patients undergoing angiography. N Engl J Med 2003;348:491–99 doi:10.1056/NEJMoa021833 pmid:12571256

    CrossRefPubMedWeb of Science
23. 23.↵
    1. McCullough PA,
    2. David G,
    3. Todoran TM, et al

    . Iso-osmolar contrast media and adverse renal and cardiac events after percutaneous cardiovascular intervention. J Comp Eff Res 2018;7:331–41 doi:10.2217/cer-2017-0052 pmid:29117715

    CrossRefPubMed
24. 24.↵
    1. Tsai TT,
    2. Patel UD,
    3. Chang TI, et al

    . Contemporary incidence, predictors, and outcomes of acute kidney injury in patients undergoing percutaneous coronary interventions: insights from the NCDR Cath-PCI registry. JACC Cardiovasc Interv 2014;7:1–9 doi:10.1016/j.jcin.2013.06.016 pmid:24456715

    Abstract/FREE Full Text
25. 25.↵
    1. Qian G,
    2. Yang YQ,
    3. Dong W, et al

    . Comparison of iodixanol and iopromide in patients with renal insufficiency and congestive heart failure undergoing coronary angiography by hemodynamic monitoring. Angiology 2017;68:907–13 doi:10.1177/0003319717701868 pmid:28401790

    CrossRefPubMed
26. 26.↵
    1. Widmann G,
    2. Bale R,
    3. Ulmer H, et al

    . Systemic hypotension following intravenous administration of nonionic contrast medium during computed tomography: iopromide versus iodixanol. Anesth Analg 2018;126:769–75 doi:10.1213/ANE.0000000000002346 pmid:28806208

    CrossRefPubMed
27. 27.↵
    1. Rosenberg C,
    2. Martinez-Rodrigo JJ,
    3. Lonjedo Vicent E, et al

    . Randomized, double-blind study comparing patient comfort and safety between iodixanol 320 mg I/mL and iopamidol 370 mg I/mL in patients undergoing peripheral arteriography: the COMFORT II trial. J Invasive Cardiol 2017;29:9–15 pmid:28045670

    PubMed
28. 28.↵
    1. Schild HH,
    2. Kuhl CK,
    3. Hubner-Steiner U, et al

    . Adverse events after unenhanced and monomeric and dimeric contrast-enhanced CT: a prospective randomized controlled trial. Radiology 2006;240:56–64 doi:10.1148/radiol.2393050560 pmid:16720865

    CrossRefPubMed
29. 29.↵
    1. Amans MR,
    2. Cooke DL,
    3. Vella M, et al

    . Contrast staining on CT after DSA in ischemic patients with stroke progresses to infarction and rarely hemorrhages. Interv Neuroradiol 2014;20:106–15 doi:10.15274/INR-2014-10016 pmid:24556308

    CrossRefPubMed
30. 30.↵
    1. Nakano S,
    2. Iseda T,
    3. Yoneyama T, et al

    . Early CT signs in patients with acute middle cerebral artery occlusion: incidence of contrast staining and haemorrhagic transformations after intra-arterial reperfusion therapy. Clin Radiol 2006;61:156–62 doi:10.1016/j.crad.2005.08.016 pmid:16439221

    CrossRefPubMed
31. 31.↵
    1. Paciaroni M,
    2. Agnelli G,
    3. Corea F, et al

    . Early hemorrhagic transformation of brain infarction: rate, predictive factors, and influence on clinical outcome: results of a prospective multicenter study. Stroke 2008;39:2249–56 doi:10.1161/STROKEAHA.107.510321 pmid:18535273

    Abstract/FREE Full Text
32. 32.↵
    1. Lun R,
    2. Walker GB,
    3. Guenego A, et al

    . Is this contrast? Is this blood? An agreement study on post-thrombectomy computed tomography scans. Front Neurol 2020;11:593098 doi:10.3389/fneur.2020.593098 pmid:33414757

    CrossRefPubMed
33. 33.↵
    1. Zaouak Y,
    2. Sadeghi N,
    3. Sarbu N, et al

    . Differentiation between cerebral hemorrhage and contrast extravasation using dual energy computed tomography after intra-arterial neuro interventional procedures. J Belg Soc Radiol 2020;104:70 doi:10.5334/jbsr.2083 pmid:33283150

    CrossRefPubMed