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Research ArticleADULT BRAIN

Absence of Meckel Cave: A Rare Cause of Trigeminal Neuralgia

A. Jain, M.S. Muneer, L. Okromelidze, R. McGeary, S.K. Valluri, A.A. Bhatt, V. Gupta, S.S. Grewal, W.P. Cheshire, E.H. Middlebrooks and S.J.S. Sandhu
American Journal of Neuroradiology July 2021, DOI: https://doi.org/10.3174/ajnr.A7205
A. Jain
aDepartment of Radiology (A.J., M.S.M., L.O., R.M., S.K.V., A.A.B., V.G., E.H.M., S.J.S.S.), Mayo Clinic, Jacksonville, Florida
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M.S. Muneer
aDepartment of Radiology (A.J., M.S.M., L.O., R.M., S.K.V., A.A.B., V.G., E.H.M., S.J.S.S.), Mayo Clinic, Jacksonville, Florida
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L. Okromelidze
aDepartment of Radiology (A.J., M.S.M., L.O., R.M., S.K.V., A.A.B., V.G., E.H.M., S.J.S.S.), Mayo Clinic, Jacksonville, Florida
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R. McGeary
aDepartment of Radiology (A.J., M.S.M., L.O., R.M., S.K.V., A.A.B., V.G., E.H.M., S.J.S.S.), Mayo Clinic, Jacksonville, Florida
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S.K. Valluri
aDepartment of Radiology (A.J., M.S.M., L.O., R.M., S.K.V., A.A.B., V.G., E.H.M., S.J.S.S.), Mayo Clinic, Jacksonville, Florida
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A.A. Bhatt
aDepartment of Radiology (A.J., M.S.M., L.O., R.M., S.K.V., A.A.B., V.G., E.H.M., S.J.S.S.), Mayo Clinic, Jacksonville, Florida
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  • ORCID record for A.A. Bhatt
V. Gupta
aDepartment of Radiology (A.J., M.S.M., L.O., R.M., S.K.V., A.A.B., V.G., E.H.M., S.J.S.S.), Mayo Clinic, Jacksonville, Florida
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S.S. Grewal
bDepartment of Neurosurgery (S.S.G., E.H.M.), Mayo Clinic, Jacksonville, Florida
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W.P. Cheshire
cDepartment of Neurology (W.P.C.), Mayo Clinic, Jacksonville, Florida
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E.H. Middlebrooks
aDepartment of Radiology (A.J., M.S.M., L.O., R.M., S.K.V., A.A.B., V.G., E.H.M., S.J.S.S.), Mayo Clinic, Jacksonville, Florida
bDepartment of Neurosurgery (S.S.G., E.H.M.), Mayo Clinic, Jacksonville, Florida
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S.J.S. Sandhu
aDepartment of Radiology (A.J., M.S.M., L.O., R.M., S.K.V., A.A.B., V.G., E.H.M., S.J.S.S.), Mayo Clinic, Jacksonville, Florida
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  • FIG 1.
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    FIG 1.

    Postcontrast coronal T1- (A) and coronal T2-weighted SPACE images (B) in 1 patient show the absence of Meckel cave (arrow) compared with the normal side (arrowhead). In another patient, postcontrast coronal T1- (C) and coronal T2-weighted SPACE images (D) show absence of Meckel cave (arrow) compared with the normal side (arrowhead).

  • FIG 2.
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    FIG 2.

    A, Axial CISS image shows absence of Meckel cave on the left (arrow) compared with the normal right Meckel cave (arrowhead). B, Coronal CISS image in the same patient shows atrophy of the left trigeminal nerve (arrow) compared with the normal nerve on the right (arrowhead). In another patient, coronal CISS image (C) shows absence of Meckel cave on the right (arrow) compared with the normal left Meckel cave (arrowhead). D, Coronal CISS image in the same patient shows atrophy of the right trigeminal nerve (arrow) compared with the normal nerve on the left (arrowhead).

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Cite this article
A. Jain, M.S. Muneer, L. Okromelidze, R. McGeary, S.K. Valluri, A.A. Bhatt, V. Gupta, S.S. Grewal, W.P. Cheshire, E.H. Middlebrooks, S.J.S. Sandhu
Absence of Meckel Cave: A Rare Cause of Trigeminal Neuralgia
American Journal of Neuroradiology Jul 2021, DOI: 10.3174/ajnr.A7205

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Absence of Meckel Cave: A Rare Cause of Trigeminal Neuralgia
A. Jain, M.S. Muneer, L. Okromelidze, R. McGeary, S.K. Valluri, A.A. Bhatt, V. Gupta, S.S. Grewal, W.P. Cheshire, E.H. Middlebrooks, S.J.S. Sandhu
American Journal of Neuroradiology Jul 2021, DOI: 10.3174/ajnr.A7205
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