Evaluation of Ultrafast Wave–Controlled Aliasing in Parallel Imaging 3D-FLAIR in the Visualization and Volumetric Estimation of Cerebral White Matter Lesions

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FIG 1.
Comparison of standard and Wave-FLAIR images and lesion masks. A, Standard FLAIR image with the lesion mask overlaid (B, blue). Wave-FLAIR image (C) with the lesion mask (D) overlaid (red). E, Lesion masks from standard and Wave-FLAIR images overlaid on the same image (purple indicates overlap of the lesion masks).
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FIG 2.
Comparison of MS lesions in different brain regions on standard and Wave-FLAIR images. The standard images (A, C, E, G, I, K) are on the left, and the Wave-FLAIR images (B, D, F, H, J, L) are on the right of each image pair. Lesion locations include the periventricular (A and B), juxtacortical (C and D), infratentorial (E and F), and deep white matter (G and H) and subcortical white matter (I and J) and deep gray matter (K and L).
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FIG 3.
Balloon plot showing the head-to-head comparison of standard-versus-Wave-FLAIR images. The size of each balloon represents the relative percentage of cases with a given score; P values for noninferiority testing are specified at the end of each row. The number of cases (percentage) are also noted adjacent to each balloon. The asterisk denotes significance following correction for multiple comparisons (false discovery rate threshold of 0.05).

Acquisition parameters for standard and wave SPACE FLAIR sequences