Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatric Neuroimaging

Interobserver Reliability of a MR Imaging Scoring System in Infants with Hypoxic-Ischemic Encephalopathy

E. Szakmar, H. Meunier, M. El-Dib, E. Yang and T.E. Inder
American Journal of Neuroradiology March 2021, DOI: https://doi.org/10.3174/ajnr.A7048
E. Szakmar
aFrom the Department of Pediatric Newborn Medicine (E.S., H.M., M.E.-D., T.E.I.), Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
bFirst Department of Pediatrics (E.S.), Semmelweis University, Budapest, Hungary
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for E. Szakmar
H. Meunier
aFrom the Department of Pediatric Newborn Medicine (E.S., H.M., M.E.-D., T.E.I.), Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
cDepartment of Neonatal Intensive Care Unit, (H.M.), Hôpital Alix de Champagne, Reims, France
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for H. Meunier
M. El-Dib
aFrom the Department of Pediatric Newborn Medicine (E.S., H.M., M.E.-D., T.E.I.), Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M. El-Dib
E. Yang
dDepartment of Radiology (E.Y.), Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for E. Yang
T.E. Inder
aFrom the Department of Pediatric Newborn Medicine (E.S., H.M., M.E.-D., T.E.I.), Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for T.E. Inder
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Kurinczuk JJ,
    2. White-Koning M,
    3. Badawi N
    . Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy. Early Hum Dev 2010;86:329–38 doi:10.1016/j.earlhumdev.2010.05.010 pmid:20554402
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Azzopardi D,
    2. Strohm B,
    3. Marlow N, et al
    . TOBY Study Group. Effects of hypothermia for perinatal asphyxia on childhood outcomes. N Engl J Med 2014;371:140–49 doi:10.1056/NEJMoa1315788 pmid:25006720
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Jacobs SE,
    2. Hunt R,
    3. Tarnow-Mordi W, et al
    . Cooling for newborns with hypoxic ischaemic encephalopathy. Cochrane Database Syst Rev 2007;CD003311 doi:10.1002/14651858.CD003311.pub2 pmid:17943788
    CrossRefPubMed
  4. 4.↵
    1. Alderliesten T,
    2. de Vries LS,
    3. Staats L, et al
    . MRI and spectroscopy in (near) term neonates with perinatal asphyxia and therapeutic hypothermia. Arch Dis Child Fetal Neonatal Ed 2017;102:F147–52 doi:10.1136/archdischild-2016-310514 pmid:27553589
    Abstract/FREE Full Text
  5. 5.↵
    1. de Vries LS,
    2. Groenendaal F
    . Patterns of neonatal hypoxic-ischaemic brain injury. Neuroradiology 2010;52:555–66 doi:10.1007/s00234-010-0674-9 pmid:20390260
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Barkovich AJ,
    2. Hajnal BL,
    3. Vigneron D, et al
    . Prediction of neuromotor outcome in perinatal asphyxia: evaluation of MR scoring systems. AJNR Am J Neuroradiol 1998;19:143–49 pmid:9432172
    Abstract
  7. 7.↵
    1. Shankaran S,
    2. McDonald SA,
    3. Laptook AR, et al
    . Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Neonatal magnetic resonance imaging pattern of brain injury as a biomarker of childhood outcomes following a trial of hypothermia for neonatal hypoxic-ischemic encephalopathy. J Pediatr 2015;167:987–93 doi:10.1016/j.jpeds.2015.08.013 pmid:26387012
    CrossRefPubMed
  8. 8.↵
    1. Rutherford M,
    2. Ramenghi LA,
    3. Edwards AD, et al
    . Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic-ischaemic encephalopathy: a nested substudy of a randomised controlled trial. Lancet Neurol 2010;9:39–45 doi:10.1016/S1474-4422(09)70295-9 pmid:19896902
    CrossRefPubMedWeb of Science
  9. 9.↵
    1. Goergen SK,
    2. Ang H,
    3. Wong F, et al
    . Early MRI in term infants with perinatal hypoxic-ischaemic brain injury: interobserver agreement and MRI predictors of outcome at 2 years. Clin Radiol 2014;69:72–81 doi:10.1016/j.crad.2013.09.001 pmid:24210250
    CrossRefPubMed
  10. 10.↵
    1. Weeke LC,
    2. Groenendaal F,
    3. Mudigonda K, et al
    . A novel magnetic resonance imaging score predicts neurodevelopmental outcome after perinatal asphyxia and therapeutic hypothermia. J Pediatr 2018;192:33–40 doi:10.1016/j.jpeds.2017.09.043 pmid:29246356
    CrossRefPubMed
  11. 11.↵
    1. Azzopardi DV,
    2. Strohm B,
    3. Edwards AD
    , et al. TOBY Study Group. Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med 2009;361:1349–58 doi:10.1056/NEJMoa0900854 pmid:19797281
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Gluckman PD,
    2. Wyatt JS,
    3. Azzopardi D, et al
    . Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet 2005;365:663–70 doi:10.1016/S0140-6736(05)17946-X pmid:15721471
    CrossRefPubMedWeb of Science
  13. 13.↵
    1. Shankaran S,
    2. Laptook AR,
    3. Ehrenkranz RA, et al
    . National Institute of Child Health and Human Development Neonatal Research Network. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 2005;353:1574–84 doi:10.1056/NEJMcps050929 pmid:16221780
    CrossRefPubMedWeb of Science
  14. 14.↵
    1. Mathur AM,
    2. Neil JJ,
    3. McKinstry RC, et al
    . Transport, monitoring, and successful brain MR imaging in unsedated neonates. Pediatr Radiol 2008;38:260–64 doi:10.1007/s00247-007-0705-9 pmid:18175110
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Jacobs SE,
    2. Morley CJ,
    3. Inder TE, et al
    . Infant Cooling Evaluation Collaboration. Whole-body hypothermia for term and near-term newborns with hypoxic-ischemic encephalopathy: a randomized controlled trial. Arch Pediatr Adolesc Med 2011;165:692–700 doi:10.1001/archpediatrics.2011.43 pmid:21464374
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Rao R,
    2. Trivedi S,
    3. Vesoulis Z, et al
    . Safety and short-term outcomes of therapeutic hypothermia in preterm neonates 34–35 weeks gestational age with hypoxic-ischemic encephalopathy. J Pediatr 2017;183:37–42 doi:10.1016/j.jpeds.2016.11.019 pmid:27979578
    CrossRefPubMed
  17. 17.↵
    1. Xu D,
    2. Vigneron D
    . Magnetic resonance spectroscopy imaging of the newborn brain: a technical review. Semin Perinatol 2010;34:20–27 doi:10.1053/j.semperi.2009.10.003 pmid:20109969
    CrossRefPubMed
  18. 18.↵
    1. Dubois J,
    2. Dehaene-Lambertz G,
    3. Kulikova S, et al
    . The early development of brain white matter: a review of imaging studies in fetuses, newborns and infants. Neuroscience 2014;276:48–71 doi:10.1016/j.neuroscience.2013.12.044 pmid:24378955
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Rutherford MA,
    2. Pennock JM,
    3. Counsell SJ, et al
    . Abnormal magnetic resonance signal in the internal capsule predicts poor neurodevelopmental outcome in infants with hypoxic-ischemic encephalopathy. Pediatrics 1998;102:323–28 doi:10.1542/peds.102.2.323 pmid:9685433
    Abstract/FREE Full Text
  20. 20.↵
    1. Lally PJ,
    2. Montaldo P,
    3. Oliveira V, et al
    . MARBLE consortium. Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study. Lancet Neurol 2019;18:35–45 doi:10.1016/S1474-4422(18)30325-9 pmid:30447969
    CrossRefPubMed
  21. 21.↵
    1. Martinez-Biarge M,
    2. Bregant T,
    3. Wusthoff CJ, et al
    . White matter and cortical injury in hypoxic-ischemic encephalopathy: antecedent factors and 2-year outcome. J Pediatr 2012;161:799–807 doi:10.1016/j.jpeds.2012.04.054 pmid:22682614
    CrossRefPubMedWeb of Science
PreviousNext
Back to top
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Interobserver Reliability of a MR Imaging Scoring System in Infants with Hypoxic-Ischemic Encephalopathy
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
E. Szakmar, H. Meunier, M. El-Dib, E. Yang, T.E. Inder
Interobserver Reliability of a MR Imaging Scoring System in Infants with Hypoxic-Ischemic Encephalopathy
American Journal of Neuroradiology Mar 2021, DOI: 10.3174/ajnr.A7048

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Interobserver Reliability of a MR Imaging Scoring System in Infants with Hypoxic-Ischemic Encephalopathy
E. Szakmar, H. Meunier, M. El-Dib, E. Yang, T.E. Inder
American Journal of Neuroradiology Mar 2021, DOI: 10.3174/ajnr.A7048
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Crossref (8)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Correlation of Different MRI Scoring Systems with Long-Term Cognitive Outcome in Cooled Asphyxiated Newborns
    Ok-Hap Kang, Peter Jahn, Joachim G. Eichhorn, Till Dresbach, Andreas Müller, Hemmen Sabir
    Children 2023 10 8
  • The predictive value of MRI scores for neurodevelopmental outcome in infants with neonatal encephalopathy
    Csilla Andorka, Hajnalka Barta, Timea Sesztak, Nora Nyilas, Kata Kovacs, Ludovika Dunai, Gabor Rudas, Agnes Jermendy, Miklos Szabo, Eniko Szakmar
    Pediatric Research 2025 97 1
  • Temperature dysregulation during therapeutic hypothermia predicts long-term outcome in neonates with HIE
    Ulrike Mietzsch, John J Flibotte, Janessa B Law, Mihai Puia-Dumitrescu, Sandra E Juul, Thomas R Wood
    Journal of Cerebral Blood Flow & Metabolism 2023 43 7
  • Hypocapnia in early hours of life is associated with brain injury in moderate to severe neonatal encephalopathy
    Eniko Szakmar, Chelsea Munster, Hoda El-Shibiny, Agnes Jermendy, Terrie Inder, Mohamed El-Dib
    Journal of Perinatology 2022 42 7
  • Do we need a brain MRI once or twice in infants treated with hypothermia?
    Linda S. de Vries, Floris Groenendaal
    Pediatric Research 2023 94 3
  • Amplitude-Integrated Electroencephalography Evolution and Magnetic Resonance Imaging Injury in Mild and Moderate to Severe Neonatal Encephalopathy
    Kullasate Sakpichaisakul, Mohamed El-Dib, Chelsea Munster, Krittin J. Supapannachart, Edward Yang, Brain H. Walsh, Joseph J. Volpe, Terrie E. Inder
    American Journal of Perinatology 2024 41 S 01
  • Growth trajectories and need for oral feeding support among infants with neonatal encephalopathy treated with therapeutic hypothermia
    Jennifer Prial, Hoda El-Shibiny, Mohamed El-Dib, Jennifer Benjamin, Carmina Erdei, Pamela Dodrill, Eniko Szakmar, Katherine A. Bell
    Journal of Perinatology 2024 44 8
  • Volpe's Neurology of the Newborn
    Anna Mrelashvili, Donna Ferriero, Terrie E. Inder, Joseph J. Volpe
    2025

More in this TOC Section

  • Neuroimaging Delineation and Progression of SLSMD
  • fetal brain development of 10 weeks gestation
  • CHARGE fetal MRI clival cleft
Show more PEDIATRIC NEUROIMAGING

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire