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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleRADIOLOGY-PATHOLOGY CORRELATION
Open Access

COVID-19-Associated Carotid Atherothrombosis and Stroke

C. Esenwa, N.T. Cheng, E. Lipsitz, K. Hsu, R. Zampolin, A. Gersten, D. Antoniello, A. Soetanto, K. Kirchoff, A. Liberman, P. Mabie, T. Nisar, D. Rahimian, A. Brook, S.-K. Lee, N. Haranhalli, D. Altschul and D. Labovitz
American Journal of Neuroradiology August 2020, DOI: https://doi.org/10.3174/ajnr.A6752
C. Esenwa
aFrom the Departments of Neurology (C.E., N.T.C., D. Antoniello, A.S., K.K., A.L., P.M., T.N., D.R., D.L.)
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N.T. Cheng
aFrom the Departments of Neurology (C.E., N.T.C., D. Antoniello, A.S., K.K., A.L., P.M., T.N., D.R., D.L.)
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E. Lipsitz
eCardiothoracic and Vascular Surgery (E.L.), Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York
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K. Hsu
bRadiology (K.H., R.Z., A.B., S.-K.L.)
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R. Zampolin
bRadiology (K.H., R.Z., A.B., S.-K.L.)
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A. Gersten
cPathology (A.G.)
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D. Antoniello
aFrom the Departments of Neurology (C.E., N.T.C., D. Antoniello, A.S., K.K., A.L., P.M., T.N., D.R., D.L.)
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A. Soetanto
aFrom the Departments of Neurology (C.E., N.T.C., D. Antoniello, A.S., K.K., A.L., P.M., T.N., D.R., D.L.)
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K. Kirchoff
aFrom the Departments of Neurology (C.E., N.T.C., D. Antoniello, A.S., K.K., A.L., P.M., T.N., D.R., D.L.)
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A. Liberman
aFrom the Departments of Neurology (C.E., N.T.C., D. Antoniello, A.S., K.K., A.L., P.M., T.N., D.R., D.L.)
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P. Mabie
aFrom the Departments of Neurology (C.E., N.T.C., D. Antoniello, A.S., K.K., A.L., P.M., T.N., D.R., D.L.)
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T. Nisar
aFrom the Departments of Neurology (C.E., N.T.C., D. Antoniello, A.S., K.K., A.L., P.M., T.N., D.R., D.L.)
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D. Rahimian
aFrom the Departments of Neurology (C.E., N.T.C., D. Antoniello, A.S., K.K., A.L., P.M., T.N., D.R., D.L.)
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A. Brook
bRadiology (K.H., R.Z., A.B., S.-K.L.)
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S.-K. Lee
bRadiology (K.H., R.Z., A.B., S.-K.L.)
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N. Haranhalli
dNeurosurgery (N.H., D. Altschul)
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D. Altschul
dNeurosurgery (N.H., D. Altschul)
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D. Labovitz
aFrom the Departments of Neurology (C.E., N.T.C., D. Antoniello, A.S., K.K., A.L., P.M., T.N., D.R., D.L.)
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References

  1. 1.↵
    1. Barnett HJ,
    2. Taylor DW,
    3. Haynes RB, et al
    ; North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 1991;325:445–53 doi:10.1056/NEJM199108153250701 pmid:1852179
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Fisher CM
    . Transient monocular blindness associated with hemiplegia. AMA Arch Ophthalmol 1952;47:167–203 doi:10.1001/archopht.1952.01700030174005 pmid:14894017
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Esenwa CC,
    2. Elkind MS
    . Inflammatory risk factors, biomarkers and associated therapy in ischaemic stroke. Nat Rev Neurol 2016;12:594–604 doi:10.1038/nrneurol.2016.125 pmid:27615422
    CrossRefPubMed
  4. 4.↵
    1. Clerkin KJ,
    2. Fried JA,
    3. Raikhelkar J, et al
    . Coronavirus disease 2019 (Covid-19) and cardiovascular disease. Circulation 2020;141:1648–55 doi:10.1161/CIRCULATIONAHA.120.046941
    CrossRefPubMed
  5. 5.↵
    1. Oxley TJ,
    2. Mocco J,
    3. Majidi S, et al
    . Large-vessel stroke as a presenting feature of Covid-19 in the young. N Engl J Med 2020;382:e60 doi:10.1056/NEJMc2009787 pmid:32343504
    CrossRefPubMed
  6. 6.↵
    1. Wang A,
    2. Mandigo GK,
    3. Yim PD, et al
    . Stroke and mechanical thrombectomy in patients with COVID-19: technical observations and patient characteristics. J Neurointerv Surg 2020;12:648–53 doi:10.1136/neurintsurg-2020-016220 pmid:32451359
    Abstract/FREE Full Text
  7. 7.↵
    1. Hoffmann M,
    2. Kleine-Weber H,
    3. Schroeder S, et al
    . SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 2020;181:271–80.e278 doi:10.1016/j.cell.2020.02.052 pmid:32142651
    CrossRefPubMed
  8. 8.↵
    1. Tikellis C,
    2. Thomas MC
    . Angiotensin-converting enzyme 2 (ACE2) is a key modulator of the renin angiotensin system in health and disease. Int J Pept 2012;2012:256294 doi:10.1155/2012/256294 pmid:22536270
    CrossRefPubMed
  9. 9.↵
    1. Varga Z,
    2. Flammer AJ,
    3. Steiger P, et al
    . Endothelial cell infection and endotheliitis in Covid-19. Lancet 2020;395:1417–18 doi:10.1016/S0140-6736(20)30937-5 pmid:32325026
    CrossRefPubMed
  10. 10.↵
    1. Buja LM,
    2. Wolf DA,
    3. Zhao B, et al
    . The emerging spectrum of cardiopulmonary pathology of the coronavirus disease 2019 (COVID-19): report of 3 autopsies from Houston, Texas, and review of autopsy findings from other United States cities. Cardiovasc Pathol 2020;48:107233 doi:10.1016/j.carpath.2020.107233 pmid:32434133
    CrossRefPubMed
  11. 11.↵
    1. Connors J,
    2. Levy J
    . Covid-19 and its implications for thrombosis and anticoagulation. Blood 2020;135:2033–40 doi:10.1182/blood.2020006000 pmid:32339221
    CrossRefPubMed
  12. 12.↵
    1. Magro C,
    2. Mulvey JJ,
    3. Berlin D, et al
    . Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases. Transl Res 2020;220:1–13 doi:10.1016/j.trsl.2020.04.007 pmid:32299776
    CrossRefPubMed
  13. 13.↵
    1. Carsana L,
    2. Sonzogni A,
    3. Nasr A, et al
    . Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy: a two-centre descriptive study. Lancet Infect Dis 2020 June 8. [Epub ahead of print] doi:10.1016/S1473-3099(20)30434-5 pmid:32526193
    CrossRefPubMed
  14. 14.↵
    1. Connors JM,
    2. Levy JH
    . Thromboinflammation and the hypercoagulability of COVID-19. J Thromb Haemost 2020;18:1559–61 doi:10.1111/jth.14849 pmid:32302453
    CrossRefPubMed
  15. 15.↵
    1. Jackson SP,
    2. Darbousset R,
    3. Schoenwaelder SM
    . Thromboinflammation: challenges of therapeutically targeting coagulation and other host defense mechanisms. Blood 2019;133:906–18 doi:10.1182/blood-2018-11-882993 pmid:30642917
    Abstract/FREE Full Text
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C. Esenwa, N.T. Cheng, E. Lipsitz, K. Hsu, R. Zampolin, A. Gersten, D. Antoniello, A. Soetanto, K. Kirchoff, A. Liberman, P. Mabie, T. Nisar, D. Rahimian, A. Brook, S.-K. Lee, N. Haranhalli, D. Altschul, D. Labovitz
COVID-19-Associated Carotid Atherothrombosis and Stroke
American Journal of Neuroradiology Aug 2020, DOI: 10.3174/ajnr.A6752

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COVID-19-Associated Carotid Atherothrombosis and Stroke
C. Esenwa, N.T. Cheng, E. Lipsitz, K. Hsu, R. Zampolin, A. Gersten, D. Antoniello, A. Soetanto, K. Kirchoff, A. Liberman, P. Mabie, T. Nisar, D. Rahimian, A. Brook, S.-K. Lee, N. Haranhalli, D. Altschul, D. Labovitz
American Journal of Neuroradiology Aug 2020, DOI: 10.3174/ajnr.A6752
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