Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePEDIATRICS

Brain Diffusion Abnormalities in Children with Tension-Type and Migraine-Type Headaches

J.D. Santoro, N.D. Forkert, Q.-Z. Yang, S. Pavitt, S.J. MacEachern, M.E. Moseley and K.W. Yeom
American Journal of Neuroradiology March 2018, DOI: https://doi.org/10.3174/ajnr.A5582
J.D. Santoro
aFrom the Department of Neurology (J.D.S., Q.-Z.Y., S.P.), Division of Child Neurology
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.D. Santoro
N.D. Forkert
cDepartments of Radiology (N.D.F.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for N.D. Forkert
Q.-Z. Yang
aFrom the Department of Neurology (J.D.S., Q.-Z.Y., S.P.), Division of Child Neurology
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Q.-Z. Yang
S. Pavitt
aFrom the Department of Neurology (J.D.S., Q.-Z.Y., S.P.), Division of Child Neurology
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for S. Pavitt
S.J. MacEachern
dPediatrics (S.J.M.), Cumming School of Medicine, University of Calgary, Alberta, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for S.J. MacEachern
M.E. Moseley
bDepartment of Radiology (M.E.M.), Stanford University School of Medicine, Stanford, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M.E. Moseley
K.W. Yeom
eDepartment of Radiology (K.W.Y.), Lucile Packard Children's Hospital, Stanford University, Stanford, California.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for K.W. Yeom
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    Headache Classification Committee of the International Headache Society (IHS). International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 2013:33:629–808 doi:10.1177/0333102413485658 pmid:23771276
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Lewis DW,
    2. Dorbad D
    . The utility of neuroimaging in the evaluation of children with migraine or chronic daily headache who have normal neurologic examinations. Headache 2000;40:629–32 doi:10.1046/j.1526-4610.2000.040008629.x pmid:10971658
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Schwedt TJ,
    2. Guo Y,
    3. Rothner AD
    . “Benign” imaging abnormalities in children and adolescents with headache. Headache 2006;46:387–98 doi:10.1111/j.1526-4610.2006.00371.x pmid:16618255
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Fazekas F,
    2. Koch M,
    3. Schmidt R, et al
    . The prevalence of cerebral damage varies with migraine type: a MRI study. Headache 1992;32:287–91 pmid:1399549
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Jäger HR,
    2. Griffin NJ,
    3. Goadsby PJ
    . Diffusion and perfusion weighted MR imaging in persistent migrainous visual disturbances. Cephalagia 2005;25:323–32 pmid:15839846
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Oberndorfer S,
    2. Wober C,
    3. Nasel C, et al
    . Familial hemiplegic migraine: follow-up findings of diffusion-weighted magnetic resonance imaging (MRI), perfusion-MRI and [99mTc] HMPAO-SPECT in a patient with prolonged hemiplegic aura. Cephalalgia 2004;24:533–39 pmid:15196295
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Rocca MA,
    2. Colombo B,
    3. Pratesi A, et al
    . A magnetization transfer imaging study of the brain in patients with migraine. Neurology 2000;54:507–09 pmid:10668727
    Abstract/FREE Full Text
  8. 8.↵
    1. Messina R,
    2. Rocca MA,
    3. Colombo B, et al
    . White matter microstructure abnormalities in pediatric migraine patients. Cephalalgia 2015;35:1278–86 doi:10.1177/0333102415578428 pmid:25795038
    CrossRefPubMed
  9. 9.↵
    1. Degirmenci B,
    2. Yaman M,
    3. Haktanir A, et al
    . Cerebral and cerebellar ADC values during a migraine attack. Neuroradiology 2007;49:419–26 doi:10.1007/s00234-006-0201-1 pmid:17225143
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Belvís R,
    2. Ramos R,
    3. Villa C, et al
    . Brain apparent water diffusion coefficient magnetic resonance imaging during a prolonged visual aura. Headache 2010;50:1045–49 doi:10.1111/j.1526-4610.2010.01672.x pmid:20408884
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Forkert ND,
    2. Li MD,
    3. Lober RM, et al
    . Gray matter growth is accompanied by increasing blood flow and decreasing apparent diffusion coefficient during childhood. AJNR Am J Neuroradiol 2016;37:1738–44 doi:10.3174/ajnr.A4772 pmid:27102314
    Abstract/FREE Full Text
  12. 12.↵
    1. Grech-Sollars M,
    2. Hales PW,
    3. Miyazaki K, et al
    . Multi-centre reproducibility of diffusion MRI parameters for clinical sequences in the brain. NMR Biomed 2015;28:468–85 doi:10.1002/nbm.3269 pmid:25802212
    CrossRefPubMed
  13. 13.↵
    1. Stejskal EO,
    2. Tanner JE
    . Spin diffusion measurements: spin echoes in the presence of a time-dependent field gradient. Journal of Chemical Physics 1965;42:288–92
    CrossRefWeb of Science
  14. 14.↵
    1. Mazziotta J,
    2. Toga A,
    3. Evans A, et al
    . A probabilistic atlas and reference system for the human brain: International Consortium for Brain Mapping (ICBM). Philos Trans R Soc Lond B Biol Sci 2001;356:1293–322 doi:10.1098/rstb.2001.0915 pmid:11545704
    Abstract/FREE Full Text
  15. 15.↵
    1. Sakov A,
    2. Golani I,
    3. Lipkind D, et al
    . High-throughput data analysis in behavior genetics. Ann Appl Stat 2010;4:743–63 doi:10.1214/09-AOAS304
    CrossRef
  16. 16.↵
    1. Wilcox SL,
    2. Veggeberg R,
    3. Lemme J, et al
    . Increased functional activation of limbic brain regions during negative emotional processing in migraine. Front Hum Neurosci 2016;10:366 doi:10.3389/fnhum.2016.00366 pmid:27507939
    CrossRefPubMed
  17. 17.↵
    1. Demarquay G,
    2. Mauguière F
    . Central nervous system underpinnings of sensory hypersensitivity in migraine: insights from neuroimaging and electrophysiological studies. Headache 2016;56:1418–38 doi:10.1111/head.12651 pmid:26350583
    CrossRefPubMed
  18. 18.↵
    1. Akerman S,
    2. Holland PR,
    3. Goadsby PJ
    . Diencephalic and brainstem mechanisms in migraine. Nat Rev Neurosci 2011;12:570–84 doi:10.1038/nrn3057 pmid:21931334
    CrossRefPubMed
  19. 19.↵
    1. Cutrer FM,
    2. O'Donnell A,
    3. Sanchez del Rio M
    . Functional neuroimaging: enhanced understanding of migraine pathophysiology. Neurology 2000;55(9 suppl 2):S36–45 pmid:11089518
    PubMedWeb of Science
  20. 20.↵
    1. Weiller C,
    2. May A,
    3. Limmroth V, et al
    . Brain stem activation in spontaneous human migraine attacks. Nat Med 1995;1:658–60 doi:10.1038/nm0795-658 pmid:7585147
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. Maleki N,
    2. Becerra L,
    3. Brawn J, et al
    . Common hippocampal structural and functional changes in migraine. Brain Struct Funct 2013;218:903–12 doi:10.1007/s00429-012-0437-y pmid:22760159
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. Schmidt-Wilcke T,
    2. Leinisch E,
    3. Straube A, et al
    . Gray matter decrease in patients with chronic tension type headache. Neurology 2005;65:1483–86 doi:10.1212/01.wnl.0000183067.94400.80 pmid:16275843
    Abstract/FREE Full Text
  23. 23.↵
    1. Amin FM,
    2. Hougaard A,
    3. Magon S, et al
    . Altered thalamic connectivity during spontaneous attacks of migraine without aura: a resting state fMRI study. Cephalalgia 2017 Jan 1. [Epub ahead of print] doi:10.1177/0333102417729113 pmid:28853611
    CrossRefPubMed
  24. 24.↵
    1. Magon S,
    2. May A,
    3. Stankewitz A, et al
    . Morphological abnormalities of thalamic subnuclei in migraine: a multicenter MRI study at 3 Tesla. J Neurosci 2015;35:13800–06 doi:10.1523/JNEUROSCI.2154-15.2015 pmid:26446230
    Abstract/FREE Full Text
  25. 25.↵
    1. Chen Z,
    2. Jia Z,
    3. Chen X, et al
    . Volumetric abnormalities of thalamic subnuclei in medication overuse headache. J Headache Pain 2017;18:82 doi:10.1186/s10194-017-0791-5 pmid:28808921
    CrossRefPubMed
  26. 26.↵
    1. Schmitz N,
    2. Admiraal-Behloul F,
    3. Arkink EB, et al
    . Attack frequency and disease duration as indicators for brain damage in migraine. Headache 2008;48:1044–55 doi:10.1111/j.1526-4610.2008.01133.x pmid:18479421
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Coppola G,
    2. Di Renzo A,
    3. Tinelli E, et al
    . Thalamo-cortical network activity between migraine attacks: insights from MRI-based microstructural and functional resting-state network correlation analysis. J Headache Pain 2016;17:100 doi:10.1186/s10194-016-0693-y pmid:27778244
    CrossRefPubMed
  28. 28.↵
    1. Genizi J,
    2. Khourieh Matar A,
    3. Zelnik N, et al
    . Frequency of pediatric migraine with aura in a clinic-based sample. Headache 2016;56:113–17 doi:10.1111/head.12741 pmid:26790850
    CrossRefPubMed
  29. 29.↵
    1. Split W,
    2. Neuman W
    . Epidemiology of migraine among students from randomly selected secondary schools in Lodz. Headache 1999;39:494–501 doi:10.1046/j.1526-4610.1999.3907494.x pmid:11279934
    CrossRefPubMedWeb of Science
  30. 30.↵
    1. Zwart JA,
    2. Dyb G,
    3. Holmen TL, et al
    . The prevalence of migraine and tension-type headaches among adolescents in Norway: the Nord-Trøndelag Health Study (Head-HUNT-Youth), a large population-based epidemiological study. Cephalalgia 2004;24:373–79 doi:10.1111/j.1468-2982.2004.00680.x pmid:15096226
    CrossRefPubMedWeb of Science
  31. 31.↵
    1. Fendrich K,
    2. Vennemann M,
    3. Pfaffenrath V, et al
    . Headache prevalence among adolescents: the German DMKG headache study. Cephalalgia 2007;27:347–54 doi:10.1111/j.1468-2982.2007.01289.x pmid:17376112
    CrossRefPubMedWeb of Science
Next
Back to top
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Brain Diffusion Abnormalities in Children with Tension-Type and Migraine-Type Headaches
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
J.D. Santoro, N.D. Forkert, Q.-Z. Yang, S. Pavitt, S.J. MacEachern, M.E. Moseley, K.W. Yeom
Brain Diffusion Abnormalities in Children with Tension-Type and Migraine-Type Headaches
American Journal of Neuroradiology Mar 2018, DOI: 10.3174/ajnr.A5582

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Brain Diffusion Abnormalities in Children with Tension-Type and Migraine-Type Headaches
J.D. Santoro, N.D. Forkert, Q.-Z. Yang, S. Pavitt, S.J. MacEachern, M.E. Moseley, K.W. Yeom
American Journal of Neuroradiology Mar 2018, DOI: 10.3174/ajnr.A5582
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • Appendix
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Early Ultrasonic Monitoring of Brain Growth and Later Neurodevelopmental Outcome in Very Preterm Infants
  • Diagnostic Value of Sylvian Fissure Hyperechogenicity in Fetal SAH
  • Feasibility and Added Value of Fetal DTI Tractography in the Evaluation of an Isolated Short Corpus Callosum: Preliminary Results
Show more Pediatrics

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire