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Research ArticleBrain
Open Access

Computer-Aided Diagnosis Improves Detection of Small Intracranial Aneurysms on MRA in a Clinical Setting

I.L. Štep̌án-Buksakowska, J.M. Accurso, F.E. Diehn, J. Huston, T.J. Kaufmann, P.H. Luetmer, C.P. Wood, X. Yang, D.J. Blezek, R. Carter, C. Hagen, D. Hořínek, A. Hejčl, M. Roček and B.J. Erickson
American Journal of Neuroradiology June 2014, DOI: https://doi.org/10.3174/ajnr.A3996
I.L. Štep̌án-Buksakowska
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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J.M. Accurso
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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F.E. Diehn
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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J. Huston
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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T.J. Kaufmann
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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P.H. Luetmer
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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C.P. Wood
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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X. Yang
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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D.J. Blezek
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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R. Carter
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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C. Hagen
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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D. Hořínek
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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A. Hejčl
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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M. Roček
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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B.J. Erickson
From the Department of Radiology (I.L.Š.-B., F.E.D., J.H., T.J.K., P.H.L., C.P.W., B.J.E.), Division of Biomedical Statistics and Informatics (R.C., C.H.), and Department of Information Services (X.Y., D.J.B.), Mayo Clinic, Rochester, Minnesota; International Clinical Research Center (I.L.Š.-B., D.H., A.H.), St. Anne's University Hospital Brno, Brno, Czech Republic; Department of Radiology (I.L.Š.-B., M.R.), Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic; Department of Radiology (J.M.A.), Mayo Clinic, Jacksonville, Florida; Department of Neurosurgery (D.H., A.H.), Masaryk Hospital, Ústí nad Labem, Czech Republic; and Department of Neurosurgery (D.H.), Central Military Hospital, Prague, Czech Republic.
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I.L. Štep̌án-Buksakowska, J.M. Accurso, F.E. Diehn, J. Huston, T.J. Kaufmann, P.H. Luetmer, C.P. Wood, X. Yang, D.J. Blezek, R. Carter, C. Hagen, D. Hořínek, A. Hejčl, M. Roček, B.J. Erickson
Computer-Aided Diagnosis Improves Detection of Small Intracranial Aneurysms on MRA in a Clinical Setting
American Journal of Neuroradiology Jun 2014, DOI: 10.3174/ajnr.A3996

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Computer-Aided Diagnosis Improves Detection of Small Intracranial Aneurysms on MRA in a Clinical Setting
I.L. Štep̌án-Buksakowska, J.M. Accurso, F.E. Diehn, J. Huston, T.J. Kaufmann, P.H. Luetmer, C.P. Wood, X. Yang, D.J. Blezek, R. Carter, C. Hagen, D. Hořínek, A. Hejčl, M. Roček, B.J. Erickson
American Journal of Neuroradiology Jun 2014, DOI: 10.3174/ajnr.A3996
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