Fusion of FDG and FMZ PET Reduces False-Positives in Predicting Epileptogenic Zone

References

1. 1.↵
   1. Beghi E

   . The epidemiology of epilepsy. Neuroepidemiology 2020;54:185–91 doi:10.1159/000503831 pmid:31852003

   CrossRefPubMed
2. 2.↵
   1. Zijlmans M,
   2. Zweiphenning W,
   3. van Klink N

   . Changing concepts in presurgical assessment for epilepsy surgery. Nat Rev Neurol 2019;15:594–606 doi:10.1038/s41582-019-0224-y pmid:31341275

   CrossRefPubMed
3. 3.↵
   1. Bartolomei F,
   2. Chauvel P,
   3. Wendling F

   . Epileptogenicity of brain structures in human temporal lobe epilepsy: a quantified study from intracerebral EEG. Brain 2008;131:1818–30 doi:10.1093/brain/awn111 pmid:18556663

   CrossRefPubMedWeb of Science
4. 4.↵
   1. Mullin JP,
   2. Shriver M,
   3. Alomar S, et al

   . Is SEEG safe? A systematic review and meta-analysis of stereo-electroencephalography-related complications. Epilepsia 2016;57:386–401 doi:10.1111/epi.13298 pmid:26899389

   CrossRefPubMed
5. 5.↵
   1. Lamusuo S,
   2. Jutila L,
   3. Ylinen A, et al

   . [18F]FDG-PET reveals temporal hypometabolism in patients with temporal lobe epilepsy even when quantitative MRI and histopathological analysis show only mild hippocampal damage. Arch Neurol 2001;58:933–39 doi:10.1001/archneur.58.6.933 pmid:11405808

   CrossRefPubMedWeb of Science
6. 6.↵
   1. Traub-Weidinger T,
   2. Arbizu J,
   3. Barthel H, et al

   . EANM practice guidelines for an appropriate use of PET and SPECT for patients with epilepsy. Eur J Nucl Med Mol Imaging 2024;51:1891–908 doi:10.1007/s00259-024-06656-3 pmid:38393374

   CrossRefPubMed
7. 7.↵
   1. Chassoux F,
   2. Artiges E,
   3. Semah F, et al

   . Determinants of brain metabolism changes in mesial temporal lobe epilepsy. Epilepsia 2016;57:907–19 doi:10.1111/epi.13377 pmid:27061896

   CrossRefPubMed
8. 8.↵
   1. Zhang M,
   2. Huang H,
   3. Liu W, et al

   . Combined quantitative T2 mapping and [(18)F]FDG PET could improve lateralization of mesial temporal lobe epilepsy. Eur Radiology 2022;32:6108–17 doi:10.1007/s00330-022-08707-5 pmid:35347363

   CrossRefPubMed
9. 9.↵
   1. Huang H,
   2. Zhang M,
   3. Zhao Y, et al

   . Simultaneous high-resolution whole-brain MR spectroscopy and [18F]FDG PET for temporal lobe epilepsy. Eur J Nucl Med Mol Imaging 2024;51:721–33 doi:10.1007/s00259-023-06465-0 pmid:37823910

   CrossRefPubMed
10. 10.↵
    1. Chassoux F,
    2. Rodrigo S,
    3. Semah F, et al

    . FDG-PET improves surgical outcome in negative MRI Taylor-type focal cortical dysplasias. Neurology 2010;75:2168–75 doi:10.1212/WNL.0b013e31820203a9 pmid:21172840

    Abstract/FREE Full Text
11. 11.↵
    1. Lagarde S,
    2. Boucekine M,
    3. McGonigal A, et al

    . Relationship between PET metabolism and SEEG epileptogenicity in focal lesional epilepsy. Eur J Nucl Med Mol Imaging 2020;47:3130–42 doi:10.1007/s00259-020-04791-1 pmid:32430581

    CrossRefPubMed
12. 12.↵
    1. Ryvlin P,
    2. Bouvard S,
    3. Le Bars D, et al

    . Clinical utility of flumazenil-PET versus [18F]fluorodeoxyglucose-PET and MRI in refractory partial epilepsy. A prospective study in 100 patients. Brain 1998;121:2067–81 doi:10.1093/brain/121.11.2067 pmid:9827767

    CrossRefPubMedWeb of Science
13. 13.↵
    1. Vivash L,
    2. Gregoire MC,
    3. Lau EW, et al

    . 18F-flumazenil: a γ-aminobutyric acid A-specific PET radiotracer for the localization of drug-resistant temporal lobe epilepsy. J Nucl Med 2013;54:1270–77 doi:10.2967/jnumed.112.107359 pmid:23857513

    Abstract/FREE Full Text
14. 14.↵
    1. Jansen LA,
    2. Peugh LD,
    3. Roden WH, et al

    . Impaired maturation of cortical GABAA receptor expression in pediatric epilepsy. Epilepsia 2010;51:1456–67 doi:10.1111/j.1528-1167.2009.02491.x pmid:20132297

    CrossRefPubMedWeb of Science
15. 15.↵
    1. Deeb TZ,
    2. Maguire J,
    3. Moss SJ

    . Possible alterations in GABAA receptor signaling that underlie benzodiazepine-resistant seizures. Epilepsia 2012;53 Suppl 9:79–88 doi:10.1111/epi.12037 pmid:23216581

    CrossRefPubMed
16. 16.↵
    1. Alhourani A,
    2. Fish KN,
    3. Wozny TA, et al

    . GABA bouton subpopulations in the human dentate gyrus are differentially altered in mesial temporal lobe epilepsy. J Neurophysiol 2020;123:392–406 doi:10.1152/jn.00523.2018 pmid:31800363

    CrossRefPubMed
17. 17.↵
    1. Benarroch EE

    . GABAA receptor heterogeneity, function, and implications for epilepsy. Neurology 2007;68:612–14 doi:10.1212/01.wnl.0000255669.83468.dd pmid:17310035

    FREE Full Text
18. 18.↵
    1. Niu N,
    2. Xing H,
    3. Wu M, et al

    . Performance of PET imaging for the localization of epileptogenic zone in patients with epilepsy: a meta-analysis. Eur Radiology 2021;31:6353–66 doi:10.1007/s00330-020-07645-4 pmid:33523306

    CrossRefPubMed
19. 19.↵
    1. Hodolic M,
    2. Topakian R,
    3. Pichler R

    . (18)F-fluorodeoxyglucose and (18)F-flumazenil positron emission tomography in patients with refractory epilepsy. Radiology Oncol 2016;50:247–53 doi:10.1515/raon-2016-0032 pmid:27679539

    CrossRefPubMed
20. 20.↵
    1. Avendaño-Estrada A,
    2. Velasco F,
    3. Velasco Ana L, et al

    . Quantitative analysis of [18F]FFMZ and [18F]FDG PET studies in the localization of seizure onset zone in drug-resistant temporal lobe epilepsy. Stereotact Funct Neurosurg 2019;97:232–40 doi:10.1159/000503692 pmid:31722358

    CrossRefPubMed
21. 21.↵
    1. Li G,
    2. Jiang S,
    3. Chen C, et al

    . iEEGview: an open-source multifunction GUI-based Matlab toolbox for localization and visualization of human intracranial electrodes. J Neural Eng 2019;17:016016 doi:10.1088/1741-2552/ab51a5 pmid:31658449

    CrossRefPubMed
22. 22.↵
    1. Destrieux C,
    2. Fischl B,
    3. Dale A, et al

    . Automatic parcellation of human cortical gyri and sulci using standard anatomical nomenclature. Neuroimage 2010;53:1–15 doi:10.1016/j.neuroimage.2010.06.010 pmid:20547229

    CrossRefPubMedWeb of Science
23. 23.↵
    1. Mercier MR,
    2. Dubarry AS,
    3. Tadel F, et al

    . Advances in human intracranial electroencephalography research, guidelines and good practices. Neuroimage 2022;260:119438 doi:10.1016/j.neuroimage.2022.119438 pmid:35792291

    CrossRefPubMed
24. 24.↵
    1. Lagarde S,
    2. Roehri N,
    3. Lambert I, et al

    . Interictal stereotactic-EEG functional connectivity in refractory focal epilepsies. Brain 2018;141:2966–80 doi:10.1093/brain/awy214 pmid:30107499

    CrossRefPubMed
25. 25.↵
    1. Ryzhikov NN,
    2. Seneca N,
    3. Krasikova RN, et al

    . Preparation of highly specific radioactivity [18F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography. Nucl Med Biol 2005;32:109–16 doi:10.1016/j.nucmedbio.2004.11.001 pmid:15721755

    CrossRefPubMed
26. 26.↵
    1. Radua J,
    2. Vieta E,
    3. Shinohara R

    ; ENIGMA Consortium Collaborators, et al. Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA. Neuroimage 2020;218:116956 doi:10.1016/j.neuroimage.2020.116956 pmid:32470572

    CrossRefPubMed
27. 27.↵
    1. Rizzo S,
    2. Botta F,
    3. Raimondi S, et al

    . Radiomics: the facts and the challenges of image analysis. Eur Radiology Exp 2018;2:36 doi:10.1186/s41747-018-0068-z pmid:30426318

    CrossRefPubMed
28. 28.↵
    1. Garofalo S,
    2. Giovagnoli S,
    3. Orsoni M, et al

    . Interaction effect: are you doing the right thing? PLoS One 2022;17:e0271668. doi:10.1371/journal.pone.0271668 pmid:35857797

    CrossRefPubMed
29. 29.↵
    1. Iacobucci D,
    2. Schneider MJ,
    3. Popovich DL, et al

    . Mean centering helps alleviate “micro” but not “macro” multicollinearity. Behav Res Methods 2016;48:1308–17 doi:10.3758/s13428-015-0624-x pmid:26148824

    CrossRefPubMed
30. 30.↵
    1. Tibshirani R

    . Regression shrinkage and selection via the LASSO. J R Stat Soc Series B Stat Methodol 1996;58:267–88 doi:10.1111/j.2517-6161.1996.tb02080.x

    CrossRef
31. 31.↵
    1. Laschet JJ,
    2. Kurcewicz I,
    3. Minier F, et al

    . Dysfunction of GABAA receptor glycolysis-dependent modulation in human partial epilepsy. Proc Natl Acad Sci U S A 2007;104:3472–77 doi:10.1073/pnas.0606451104 pmid:17360668

    Abstract/FREE Full Text
32. 32.↵
    1. Holthoff VA,
    2. Koeppe RA,
    3. Frey KA, et al

    . Positron emission tomography measures of benzodiazepine receptors in Huntington’s disease. Ann Neurol 1993;34:76–81 doi:10.1002/ana.410340114 pmid:8390806

    CrossRefPubMedWeb of Science
33. 33.↵
    1. Nedergaard S,
    2. Andreasen M

    . Opposing effects of 2-deoxy-d-glucose on interictal- and ictal-like activity when K(+) currents and GABA(A) receptors are blocked in rat hippocampus in vitro. J Neurophysiol 2018;119:1912–23 doi:10.1152/jn.00732.2017 pmid:29412775

    CrossRefPubMed
34. 34.↵
    1. Kim K,
    2. Yoon H

    . Gamma-aminobutyric acid signaling in damage response, metabolism, and disease. Int J Mol Sci 2023;24:4584 doi:10.3390/ijms24054584 pmid:36902014

    CrossRefPubMed
35. 35.↵
    1. Nørgaard M,
    2. Beliveau V,
    3. Ganz M, et al

    . A high-resolution in vivo atlas of the human brain’s benzodiazepine binding site of GABA(A) receptors. Neuroimage 2021;232:117878 doi:10.1016/j.neuroimage.2021.117878 pmid:33610745

    CrossRefPubMed