Correlation between P2-PCA Volume Flow Rate and BOLD Cerebrovascular Reactivity in Patients with Symptomatic Carotid Artery Occlusion

Amely Walser; Jorn Fierstra; Lara Maria Höbner; Jacopo Bellomo; Tilman Schubert; Menno Germans; Vittorio Stumpo; Christiaan Hendrik Bas van Niftrik; Susanne Wegener; Andreas R. Luft; Zsolt Kulcsár; Luca Regli; Giuseppe Esposito; Martina Sebök

doi:10.3174/ajnr.A8626

Research ArticleNeurovascular/Stroke Imaging

Correlation between P2-PCA Volume Flow Rate and BOLD Cerebrovascular Reactivity in Patients with Symptomatic Carotid Artery Occlusion

Amely Walser, Jorn Fierstra, Lara Maria Höbner, Jacopo Bellomo, Tilman Schubert, Menno Germans, Vittorio Stumpo, Christiaan Hendrik Bas van Niftrik, Susanne Wegener, Andreas R. Luft, Zsolt Kulcsár, Luca Regli, Giuseppe Esposito and Martina Sebök

American Journal of Neuroradiology July 2025, 46 (7) 1353-1359; DOI: https://doi.org/10.3174/ajnr.A8626

Amely Walser

aFrom the Department of Neurosurgery (G.E., M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

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Jorn Fierstra

aFrom the Department of Neurosurgery (G.E., M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

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Lara Maria Höbner

aFrom the Department of Neurosurgery (G.E., M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

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Jacopo Bellomo

aFrom the Department of Neurosurgery (G.E., M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

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Tilman Schubert

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

cDepartment of Neuroradiology (T.S., Z.K.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

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Menno Germans

aFrom the Department of Neurosurgery (G.E., M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

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Vittorio Stumpo

aFrom the Department of Neurosurgery (G.E., M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

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Christiaan Hendrik Bas van Niftrik

aFrom the Department of Neurosurgery (G.E., M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

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Susanne Wegener

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

dDepartment of Neurology (S.W., A.R.L.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

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Andreas R. Luft

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

dDepartment of Neurology (S.W., A.R.L.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

eCereneo Center for Neurology and Rehabilitation (A.R.L.), Vitznau, Switzerland

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Zsolt Kulcsár

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

cDepartment of Neuroradiology (T.S., Z.K.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

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Luca Regli

aFrom the Department of Neurosurgery (G.E., M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

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Giuseppe Esposito

aFrom the Department of Neurosurgery (G.E., M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

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Martina Sebök

aFrom the Department of Neurosurgery (G.E., M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R.), University Hospital Zurich, University of Zurich, Zurich, Switzerland

bClinical Neuroscience Center (M.S., A.W., J.F., L.M.H., J.B., M.G., V.S., C.H.B.v.N., L.R., T.S., S.W., A.R.L., Z.K.), University Hospital Zurich, Zurich, Switzerland

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Correlation between P2-PCA Volume Flow Rate and BOLD Cerebrovascular Reactivity in Patients with Symptomatic Carotid Artery Occlusion

American Journal of Neuroradiology Jul 2025, 46 (7) 1353-1359; DOI: 10.3174/ajnr.A8626

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P2-PCA VFR and BOLD-CVR in ICA Occlusion

American Journal of Neuroradiology Jul 2025, 46 (7) 1353-1359; DOI: 10.3174/ajnr.A8626

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