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Research ArticleBrain Tumor Imaging

Repeatability and Reproducibility of Pseudocontinuous Arterial Spin-Labeling–Measured Brain Perfusion in Healthy Volunteers and Patients with Glioblastoma

Limin Zhou, Durga Udayakumar, Yiming Wang, Marco C. Pinho, Benjamin C. Wagner, Michael Youssef, Joseph A. Maldjian and Ananth J. Madhuranthakam
American Journal of Neuroradiology May 2025, 46 (5) 973-982; DOI: https://doi.org/10.3174/ajnr.A8551
Limin Zhou
aFrom the Department of Radiology (L.Z., D.U., YW., M.C.P., B.C.W. J.A.M. A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
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Durga Udayakumar
aFrom the Department of Radiology (L.Z., D.U., YW., M.C.P., B.C.W. J.A.M. A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
bAdvanced Imaging Research Center (D.U., M.C.P., J.A.M., A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
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  • ORCID record for Durga Udayakumar
Yiming Wang
aFrom the Department of Radiology (L.Z., D.U., YW., M.C.P., B.C.W. J.A.M. A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
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Marco C. Pinho
aFrom the Department of Radiology (L.Z., D.U., YW., M.C.P., B.C.W. J.A.M. A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
bAdvanced Imaging Research Center (D.U., M.C.P., J.A.M., A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
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  • ORCID record for Marco C. Pinho
Benjamin C. Wagner
aFrom the Department of Radiology (L.Z., D.U., YW., M.C.P., B.C.W. J.A.M. A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
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Michael Youssef
cDepartments of Neurology (M.Y.), UT Southwestern Medical Center, Dallas, Texas
dDepartment of Hematology and Oncology (M.Y.), Utah Southwestern Medical Center, Dallas, Texas
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Joseph A. Maldjian
aFrom the Department of Radiology (L.Z., D.U., YW., M.C.P., B.C.W. J.A.M. A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
bAdvanced Imaging Research Center (D.U., M.C.P., J.A.M., A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
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Ananth J. Madhuranthakam
aFrom the Department of Radiology (L.Z., D.U., YW., M.C.P., B.C.W. J.A.M. A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
bAdvanced Imaging Research Center (D.U., M.C.P., J.A.M., A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
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Article Information

vol. 46 no. 5 973-982
DOI 
https://doi.org/10.3174/ajnr.A8551
PubMed 
39443151

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received August 16, 2024
  • Accepted after revision October 21, 2024
  • Published online May 2, 2025.

Article Versions

  • Latest version (October 23, 2024 - 11:13).
  • Latest version (April 3, 2025 - 08:02).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2025 by American Journal of Neuroradiology

Author Information

  1. Limin Zhoua,
  2. Durga Udayakumara,b,
  3. Yiming Wanga,
  4. Marco C. Pinhoa,b,
  5. Benjamin C. Wagnera,
  6. Michael Youssefc,d,
  7. Joseph A. Maldjiana,b and
  8. Ananth J. Madhuranthakama,b
  1. aFrom the Department of Radiology (L.Z., D.U., YW., M.C.P., B.C.W. J.A.M. A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
  2. bAdvanced Imaging Research Center (D.U., M.C.P., J.A.M., A.J.M.), Utah Southwestern Medical Center, Dallas, Texas
  3. cDepartments of Neurology (M.Y.), UT Southwestern Medical Center, Dallas, Texas
  4. dDepartment of Hematology and Oncology (M.Y.), Utah Southwestern Medical Center, Dallas, Texas
  1. Please address correspondence to Ananth J. Madhuranthakam, PhD, Mayo Clinic, 200 First St SW, Rochester, MN 55905; e-mail: ananth{at}mayo.edu
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Funding

  • National Institutes of Health / National Cancer Institute (NIH/NCI)

    R01CA260705; U01CA207091

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  • Verlaufsbeobachtung von Glioblastompatienten mit 2 verschiedenen ASL-Methoden
    Neuroradiologie Scan 2025 15 02
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Cite this article
Limin Zhou, Durga Udayakumar, Yiming Wang, Marco C. Pinho, Benjamin C. Wagner, Michael Youssef, Joseph A. Maldjian, Ananth J. Madhuranthakam
Repeatability and Reproducibility of Pseudocontinuous Arterial Spin-Labeling–Measured Brain Perfusion in Healthy Volunteers and Patients with Glioblastoma
American Journal of Neuroradiology May 2025, 46 (5) 973-982; DOI: 10.3174/ajnr.A8551

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ASL Repeatability Reproducibility in Brain Tumors
Limin Zhou, Durga Udayakumar, Yiming Wang, Marco C. Pinho, Benjamin C. Wagner, Michael Youssef, Joseph A. Maldjian, Ananth J. Madhuranthakam
American Journal of Neuroradiology May 2025, 46 (5) 973-982; DOI: 10.3174/ajnr.A8551
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  • Verlaufsbeobachtung von Glioblastompatienten mit 2 verschiedenen ASL-Methoden
    Neuroradiologie Scan 2025 15 02

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