Research ArticleBrain Tumor Imaging
Open Access
Gadolinium-Enhanced T2 FLAIR Is an Imaging Biomarker of Radiation Necrosis and Tumor Progression in Patients with Brain Metastases
Chris Heyn, Jonathan Bishop, Alan R. Moody, Tony Kang, Erin Wong, Peter Howard, Pejman Maralani, Sean Symons, Bradley J. MacIntosh, Julia Keith, Mary Jane Lim-Fat, James Perry, Sten Myrehaug, Jay Detsky, Chia-Lin Tseng, Hanbo Chen, Arjun Sahgal and Hany Soliman
American Journal of Neuroradiology January 2025, 46 (1) 129-135; DOI: https://doi.org/10.3174/ajnr.A8431
Chris Heyn
aFrom the Department of Medical Imaging (C.H., J.B., A.R.M., T.K., E.W., P.H., P.M., S.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
bDepartment of Medical Imaging (C.H., A.R.M., T.K., E.W., P.H., P.M., S.S.), University of Toronto, Toronto, Ontario, Canada
cSunnybrook Research Institute, Sunnybrook Health Sciences Centre (C.H., A.R.M., P.M., S.S., B.J.M.), Toronto, Ontario, Canada
Jonathan Bishop
aFrom the Department of Medical Imaging (C.H., J.B., A.R.M., T.K., E.W., P.H., P.M., S.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Alan R. Moody
aFrom the Department of Medical Imaging (C.H., J.B., A.R.M., T.K., E.W., P.H., P.M., S.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
bDepartment of Medical Imaging (C.H., A.R.M., T.K., E.W., P.H., P.M., S.S.), University of Toronto, Toronto, Ontario, Canada
cSunnybrook Research Institute, Sunnybrook Health Sciences Centre (C.H., A.R.M., P.M., S.S., B.J.M.), Toronto, Ontario, Canada
Tony Kang
aFrom the Department of Medical Imaging (C.H., J.B., A.R.M., T.K., E.W., P.H., P.M., S.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
bDepartment of Medical Imaging (C.H., A.R.M., T.K., E.W., P.H., P.M., S.S.), University of Toronto, Toronto, Ontario, Canada
Erin Wong
aFrom the Department of Medical Imaging (C.H., J.B., A.R.M., T.K., E.W., P.H., P.M., S.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
bDepartment of Medical Imaging (C.H., A.R.M., T.K., E.W., P.H., P.M., S.S.), University of Toronto, Toronto, Ontario, Canada
Peter Howard
aFrom the Department of Medical Imaging (C.H., J.B., A.R.M., T.K., E.W., P.H., P.M., S.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
bDepartment of Medical Imaging (C.H., A.R.M., T.K., E.W., P.H., P.M., S.S.), University of Toronto, Toronto, Ontario, Canada
Pejman Maralani
aFrom the Department of Medical Imaging (C.H., J.B., A.R.M., T.K., E.W., P.H., P.M., S.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
bDepartment of Medical Imaging (C.H., A.R.M., T.K., E.W., P.H., P.M., S.S.), University of Toronto, Toronto, Ontario, Canada
cSunnybrook Research Institute, Sunnybrook Health Sciences Centre (C.H., A.R.M., P.M., S.S., B.J.M.), Toronto, Ontario, Canada
Sean Symons
aFrom the Department of Medical Imaging (C.H., J.B., A.R.M., T.K., E.W., P.H., P.M., S.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
bDepartment of Medical Imaging (C.H., A.R.M., T.K., E.W., P.H., P.M., S.S.), University of Toronto, Toronto, Ontario, Canada
cSunnybrook Research Institute, Sunnybrook Health Sciences Centre (C.H., A.R.M., P.M., S.S., B.J.M.), Toronto, Ontario, Canada
Bradley J. MacIntosh
cSunnybrook Research Institute, Sunnybrook Health Sciences Centre (C.H., A.R.M., P.M., S.S., B.J.M.), Toronto, Ontario, Canada
Julia Keith
dDepartment of Anatomy and Pathology (J.K.), Sunnybrook Health Sciences Centre, Toronto Ontario, Canada
Mary Jane Lim-Fat
eDivision of Neurology (M.J.L-F, J.P.), Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
James Perry
eDivision of Neurology (M.J.L-F, J.P.), Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Sten Myrehaug
fDepartment of Radiation Oncology (S.M., J.D., C.-L.T., H.C., A.S., H.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Jay Detsky
fDepartment of Radiation Oncology (S.M., J.D., C.-L.T., H.C., A.S., H.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Chia-Lin Tseng
fDepartment of Radiation Oncology (S.M., J.D., C.-L.T., H.C., A.S., H.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Hanbo Chen
fDepartment of Radiation Oncology (S.M., J.D., C.-L.T., H.C., A.S., H.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Arjun Sahgal
fDepartment of Radiation Oncology (S.M., J.D., C.-L.T., H.C., A.S., H.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Hany Soliman
fDepartment of Radiation Oncology (S.M., J.D., C.-L.T., H.C., A.S., H.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

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In this issue
American Journal of Neuroradiology
Vol. 46, Issue 1
1 Jan 2025
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Chris Heyn, Jonathan Bishop, Alan R. Moody, Tony Kang, Erin Wong, Peter Howard, Pejman Maralani, Sean Symons, Bradley J. MacIntosh, Julia Keith, Mary Jane Lim-Fat, James Perry, Sten Myrehaug, Jay Detsky, Chia-Lin Tseng, Hanbo Chen, Arjun Sahgal, Hany Soliman
Gadolinium-Enhanced T2 FLAIR Is an Imaging Biomarker of Radiation Necrosis and Tumor Progression in Patients with Brain Metastases
American Journal of Neuroradiology Jan 2025, 46 (1) 129-135; DOI: 10.3174/ajnr.A8431
Gad FLAIR T2 for Radiation Necrosis Brain Mets
Chris Heyn, Jonathan Bishop, Alan R. Moody, Tony Kang, Erin Wong, Peter Howard, Pejman Maralani, Sean Symons, Bradley J. MacIntosh, Julia Keith, Mary Jane Lim-Fat, James Perry, Sten Myrehaug, Jay Detsky, Chia-Lin Tseng, Hanbo Chen, Arjun Sahgal, Hany Soliman
American Journal of Neuroradiology Jan 2025, 46 (1) 129-135; DOI: 10.3174/ajnr.A8431
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