Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNeurovascular/Stroke Imaging
Open Access

Value of Immediate Flat Panel Perfusion Imaging after Endovascular Therapy (AFTERMATH): A Proof of Concept Study

Adnan Mujanovic, Christoph C. Kurmann, Michael Manhart, Eike I. Piechowiak, Sara M. Pilgram-Pastor, Bettina L. Serrallach, Gregoire Boulouis, Thomas R. Meinel, David J. Seiffge, Simon Jung, Marcel Arnold, Thanh N. Nguyen, Urs Fischer, Jan Gralla, Tomas Dobrocky, Pasquale Mordasini and Johannes Kaesmacher
American Journal of Neuroradiology February 2024, 45 (2) 163-170; DOI: https://doi.org/10.3174/ajnr.A8103
Adnan Mujanovic
aFrom the Departments of Diagnostic and Interventional Neuroradiology (A.M., C.C.K., E.I.P., S.M.P.-P., B.L.S., J.G., T.D., P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
iGraduate School of Health Sciences (A.M., C.C.K.), University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Adnan Mujanovic
Christoph C. Kurmann
aFrom the Departments of Diagnostic and Interventional Neuroradiology (A.M., C.C.K., E.I.P., S.M.P.-P., B.L.S., J.G., T.D., P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
bDepartment of Diagnostic, Interventional and Pediatric Radiology (C.C.K.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
iGraduate School of Health Sciences (A.M., C.C.K.), University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Christoph C. Kurmann
Michael Manhart
cSiemens Healthineers, Advanced Therapies (M.M.), Forchheim, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Michael Manhart
Eike I. Piechowiak
aFrom the Departments of Diagnostic and Interventional Neuroradiology (A.M., C.C.K., E.I.P., S.M.P.-P., B.L.S., J.G., T.D., P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Eike I. Piechowiak
Sara M. Pilgram-Pastor
aFrom the Departments of Diagnostic and Interventional Neuroradiology (A.M., C.C.K., E.I.P., S.M.P.-P., B.L.S., J.G., T.D., P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Sara M. Pilgram-Pastor
Bettina L. Serrallach
aFrom the Departments of Diagnostic and Interventional Neuroradiology (A.M., C.C.K., E.I.P., S.M.P.-P., B.L.S., J.G., T.D., P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Bettina L. Serrallach
Gregoire Boulouis
dDepartments of Diagnostic and Interventional Neuroradiology (G.B.), University Hospital Tours (Centre Val de Loire Region), Tours, France
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Gregoire Boulouis
Thomas R. Meinel
eDepartment of Neurology (T.R.M., D.J.S., S.J., M.A., U.F.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Thomas R. Meinel
David J. Seiffge
eDepartment of Neurology (T.R.M., D.J.S., S.J., M.A., U.F.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for David J. Seiffge
Simon Jung
eDepartment of Neurology (T.R.M., D.J.S., S.J., M.A., U.F.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Simon Jung
Marcel Arnold
eDepartment of Neurology (T.R.M., D.J.S., S.J., M.A., U.F.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Marcel Arnold
Thanh N. Nguyen
fDepartment of Neurology (T.N.N.), Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, MA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Thanh N. Nguyen
Urs Fischer
eDepartment of Neurology (T.R.M., D.J.S., S.J., M.A., U.F.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
gDepartment of Neurology (U.F.), University Hospital Basel, University of Basel, Basel, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jan Gralla
aFrom the Departments of Diagnostic and Interventional Neuroradiology (A.M., C.C.K., E.I.P., S.M.P.-P., B.L.S., J.G., T.D., P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jan Gralla
Tomas Dobrocky
aFrom the Departments of Diagnostic and Interventional Neuroradiology (A.M., C.C.K., E.I.P., S.M.P.-P., B.L.S., J.G., T.D., P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Tomas Dobrocky
Pasquale Mordasini
aFrom the Departments of Diagnostic and Interventional Neuroradiology (A.M., C.C.K., E.I.P., S.M.P.-P., B.L.S., J.G., T.D., P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
hDepartment of Diagnostic and Interventional Neuroradiology (P.M.), Cantonal Hospital St. Gallen, St. Gallen, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Johannes Kaesmacher
aFrom the Departments of Diagnostic and Interventional Neuroradiology (A.M., C.C.K., E.I.P., S.M.P.-P., B.L.S., J.G., T.D., P.M., J.K.), University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Johannes Kaesmacher
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • FIG 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 1.

    Concurring ratings regarding the presence of hypoperfusion. A, Patient with a left-M1 occlusion with complete reperfusion (eTICI 3) on the final angiography imaging and normal perfused tissue on FPCT-PI. B, Patient with a left-M1 occlusion with incomplete reperfusion (eTICI 2b50) on the final angiography imaging and corresponding frontal and parietal hypoperfusion deficits on the FPCT-PI. C, Patient with a left-M1 occlusion with incomplete reperfusion (eTICI 2b67) on the final angiography series, with a clear deficit in the parietal region. On follow-up FPCT-PI, the corresponding hypoperfusion is visible in the same area (green circle), with an additional hypoperfusion noted in the temporal region (red circle). The temporal branch occlusion was not noted by the core lab, but confirmed after making FPCT-PI available. D, Patient with a right-M2 occlusion with incomplete reperfusion on the final angiography series (eTICI 2b67, green circle) and hypoperfusion on the contralateral unaffected side (red circle).

  • FIG 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 2.

    Discrepant ratings regarding the presence of hypoperfusion. A, Patient with a right-M1 occlusion rated as complete reperfusion (eTICI 3) on the final angiography imaging, but follow-up FPCT-PI revealed distal nonperfused tissue. A small residual M4 branch occlusion was confirmed by the core lab after making FPCT-PI available. B, Patient with a left-ICA occlusion rated as complete reperfusion (eTICI 3) on final angiography imaging, but follow-up FPCT-PI revealed a new hypoperfusion due to a distal frontal anterior cerebral artery branch occlusion. C, Patient with a left-M1 occlusion with incomplete reperfusion (eTICI 2b67) on the final angiography series with a clear capillary phase deficit in the frontal region. Follow-up FPCT-PI showed complete delayed reperfusion without any perfusion delays. D, Patient with a left-M1 occlusion with a small persisting deficit in the parietal region on the final angiography run (eTICI 2c, green circle). Follow-up FPCT-PI shows no perfusion delay on the left side; however, there was a hypoperfusion deficit on the contralateral side (red circle).

  • FIG 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 3.

    Study flow chart and patient allocation based on the agreement between the findings on final DSA runs and FPCT-PI.

Tables

  • Figures
  • Baseline and Interventional Characteristics

    VariablesN = 26a
    Baseline
     Age77 (61, 83)
     Sex (male)18 (69%)
     NIHSS on admission15 (11, 20)
    Intervention
     eTICI score (core-lab adjudicated grading)
      2a2 (8%)
      2b502 (8%)
      2b6710 (38%)
      2c5 (19%)
      37 (27%)
     Time from DSA to FPCTP (min)4.3 (3.2, 7.5)
     Total contrast dose for both DSA and FPCTP (mL)200 (183, 228)
    Outcome
     NIHSS at 24 hours6 (2, 15)
     90-day mRS
      02 (7.7%)
      18 (31%)
      22 (7.7%)
      34 (15%)
      43 (12%)
      51 (3.8%)
      66 (23%)
    • a Data are median (IQR); n (%).

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 45 (2)
American Journal of Neuroradiology
Vol. 45, Issue 2
1 Feb 2024
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Value of Immediate Flat Panel Perfusion Imaging after Endovascular Therapy (AFTERMATH): A Proof of Concept Study
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Adnan Mujanovic, Christoph C. Kurmann, Michael Manhart, Eike I. Piechowiak, Sara M. Pilgram-Pastor, Bettina L. Serrallach, Gregoire Boulouis, Thomas R. Meinel, David J. Seiffge, Simon Jung, Marcel Arnold, Thanh N. Nguyen, Urs Fischer, Jan Gralla, Tomas Dobrocky, Pasquale Mordasini, Johannes Kaesmacher
Value of Immediate Flat Panel Perfusion Imaging after Endovascular Therapy (AFTERMATH): A Proof of Concept Study
American Journal of Neuroradiology Feb 2024, 45 (2) 163-170; DOI: 10.3174/ajnr.A8103

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Flat Panel Perfusion Post-Endovascular Therapy
Adnan Mujanovic, Christoph C. Kurmann, Michael Manhart, Eike I. Piechowiak, Sara M. Pilgram-Pastor, Bettina L. Serrallach, Gregoire Boulouis, Thomas R. Meinel, David J. Seiffge, Simon Jung, Marcel Arnold, Thanh N. Nguyen, Urs Fischer, Jan Gralla, Tomas Dobrocky, Pasquale Mordasini, Johannes Kaesmacher
American Journal of Neuroradiology Feb 2024, 45 (2) 163-170; DOI: 10.3174/ajnr.A8103
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • DOT sign indicates persistent hypoperfusion and poor outcome in patients with incomplete reperfusion following thrombectomy
  • Intra-arterial tenecteplase after successful endovascular therapy (ANGEL-TNK): protocol of a multicentre, open-label, blinded end-point, prospective, randomised trial
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • 90-day Outcome Prediction in VBAO after EVT
  • P2-PCA VFR and BOLD-CVR in ICA Occlusion
  • Circle of Willis Variants and Stroke Outcomes
Show more Neurovascular/Stroke Imaging

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire