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Review ArticleSpine Imaging and Spine Image-Guided Interventions

Myelographic Techniques for the Localization of CSF-Venous Fistulas: Updates in 2024

Ajay A. Madhavan, Waleed Brinjikji, Jeremy K. Cutsforth-Gregory, Timothy J. Amrhein, Peter G. Kranz, John C. Benson, Felix E. Diehn, Ben A. Johnson-Tesch, Greta B. Liebo, Vance T. Lehman, Ian T. Mark, Pearse P. Morris, Michael P. Oien, Darya P. Shlapak and Jared T. Verdoorn
American Journal of Neuroradiology October 2024, 45 (10) 1403-1412; DOI: https://doi.org/10.3174/ajnr.A8299
Ajay A. Madhavan
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Waleed Brinjikji
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Jeremy K. Cutsforth-Gregory
bDepartment of Neurology (J.K.C.-G.), Mayo Clinic, Rochester, Minnesota.
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Timothy J. Amrhein
cDivision of Neuroradiology, Department of Radiology (T.J.A., P.G.K.), Duke Health, Durham, North Carolina
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Peter G. Kranz
cDivision of Neuroradiology, Department of Radiology (T.J.A., P.G.K.), Duke Health, Durham, North Carolina
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John C. Benson
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Felix E. Diehn
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Ben A. Johnson-Tesch
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Greta B. Liebo
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Vance T. Lehman
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Ian T. Mark
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Pearse P. Morris
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Michael P. Oien
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Darya P. Shlapak
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Jared T. Verdoorn
aFrom the Division of Neuroradiology, Department of Radiology (A.A.M., W.B., J.C.B., F.E.D., B.A.J.-T., G.L., V.T.L., I.T.M., P.P.M., M.P.O., D.P.S., J.T.V.), Mayo Clinic, Rochester, Minnesota
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Abstract

SUMMARY: CSF-venous fistulas (CVFs) are a common cause of spontaneous intracranial hypotension. Despite their relatively frequent occurrence, they can be exceedingly difficult to detect on imaging. Since the initial description of CVFs in 2014, the recognition and diagnosis of this type of CSF leak has continually increased. As a result of multi-institutional efforts, a wide spectrum of imaging modalities and specialized techniques for CVF detection is now available. It is important for radiologists to be familiar with the multitude of available techniques, because each has unique advantages and drawbacks. In this article, we review the spectrum of imaging modalities available for the detection of CVFs, explain the advantages and disadvantages of each, provide typical imaging examples, and discuss provocative maneuvers that may improve the conspicuity of CVFs. Discussed modalities include conventional CT myelography, dynamic myelography, digital subtraction myelography, conebeam CT myelography, decubitus CT myelography by using conventional energy-integrating detector scanners, decubitus photon counting CT myelography, and intrathecal gadolinium MR myelography. Additional topics to be discussed include optimal patient positioning, respiratory techniques, and intrathecal pressure augmentation.

ABBREVIATIONS:

AP
anteroposterior
CBCT
conebeam CT
CB-CTM
conebeam CT myelography
CTM
CT myelography
CVF
CSF-venous fistula
DSM
digital subtraction myelography
EID
energy-integrating detector
GdM
intrathecal gadolinium MR myelography
IVVP
internal vertebral venous plexus
PCCT
photon-counting detector CT
PC-CTM
photon-counting CT myelography
SIH
spontaneous intracranial hypotension
SR
standard resolution
UHR
ultra-high resolution
VMI
virtual monoenergetic image
  • © 2024 by American Journal of Neuroradiology
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American Journal of Neuroradiology: 45 (10)
American Journal of Neuroradiology
Vol. 45, Issue 10
1 Oct 2024
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Cite this article
Ajay A. Madhavan, Waleed Brinjikji, Jeremy K. Cutsforth-Gregory, Timothy J. Amrhein, Peter G. Kranz, John C. Benson, Felix E. Diehn, Ben A. Johnson-Tesch, Greta B. Liebo, Vance T. Lehman, Ian T. Mark, Pearse P. Morris, Michael P. Oien, Darya P. Shlapak, Jared T. Verdoorn
Myelographic Techniques for the Localization of CSF-Venous Fistulas: Updates in 2024
American Journal of Neuroradiology Oct 2024, 45 (10) 1403-1412; DOI: 10.3174/ajnr.A8299

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2024 Updates on Myelographic Techniques
Ajay A. Madhavan, Waleed Brinjikji, Jeremy K. Cutsforth-Gregory, Timothy J. Amrhein, Peter G. Kranz, John C. Benson, Felix E. Diehn, Ben A. Johnson-Tesch, Greta B. Liebo, Vance T. Lehman, Ian T. Mark, Pearse P. Morris, Michael P. Oien, Darya P. Shlapak, Jared T. Verdoorn
American Journal of Neuroradiology Oct 2024, 45 (10) 1403-1412; DOI: 10.3174/ajnr.A8299
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    • ABBREVIATIONS:
    • GENERAL PRINCIPLES
    • IMAGING MODALITIES FOR CVF DETECTION
    • PROVOCATIVE MANEUVERS TO AID IN CVF DETECTION
    • CONCLUSIONS
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  • Optimization of Photon-Counting CT Myelography for the Detection of CSF-Venous Fistulas Using Convolutional Neural Network Denoising: A Comparative Analysis of Reconstruction Techniques
  • Additional Diagnostic Value of Conebeam CT Myelography Performed after Digital Subtraction Myelography for Detecting CSF-Venous Fistulas
  • Density and Time Characteristics of CSF-Venous Fistulas on CT Myelography in Patients with Spontaneous Intracranial Hypotension
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