Article Figures & Data
Figures
- FIG 1.
Frequency of hypoxic-ischemic brain injury in both outcome groups. Colorized 3D brain renderings show the frequency of injury (as defined by ADC < 650 × 10–6 mm2/s) for the poor-outcome group (A) and the good outcome group (B), respectively. The color bar (right) indicates the frequency of injury across the whole brain. Note that regions with <5% injury frequency are transparent to allow better visualization of more frequently injured areas.
- FIG 2.
Results of voxelwise comparisons between outcome groups. Statistically significant voxels (family-wise error rate–corrected, P < .05) are shown as color overlays on orthogonal slices of the Montreal Neurologic Institute brain atlas (A–C). Color indicates the P value for the comparison (see the color bar). A volume-rendering of the P value from a lateral perspective is also shown, with dashed yellow lines indicating the plane of axial and coronal slices (D).
- FIG 3.
Loading values for PC2 from the PCA. Each cortical region from the Harvard Oxford brain atlas is colored according to its PC2 loading value. Red and blue loadings indicate opposite patterns of loading (red indicates positive correlation, blue indicates a negative correlation). The dashed yellow line on the lateral projection (right) indicates the plane of the axial section (center).
- FIG 4.
ROC analysis of different diffusion-weighted MR imaging–based variables for predicting outcome in patients with post–cardiac arrest coma. OHCA indicates out of hospital cardiac arrest.
Tables
Subject demographics stratified by outcome group
Variable Follows Commands (n = 17) Does Not Follow Commands (n = 64) P Value Age (mean) (yr) 55 (SD, 16) 57 (SD, 15) .741 Female sex 4/17 (24%) 18/64 (28%) .701 Race and ethnicitya .757 Asian 4 (21%) 6 (9%) Black 3 (16%) 14 (22%) Hispanic 2 (11%) 6 (9%) Hawaiian 0 (0%) 2 (3%) Non-Hispanic white 2 (11%) 6 (9%) Unknown 8 (42%) 30 (47%) Time from ROSC to MR imaging (mean) (hr) 120 (SD, 26) 115 (SD, 27) .496 Shockable rhythm 6/17 (35%) 12/64 (19%) .145 Out-of-hospital cardiac arrest 14/17 (82%) 49/64 (77%) .610 Time to ROSC (mean) 19 (SD, 14) 24 (SD, 14) .182 ↵a Patient race and ethnicity do not add to 100% as some patients reported more than one race and ethnicity combination.
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