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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatric Neuroimaging

Imaging Findings and Clinical Analysis of Primary Intracranial Pure Yolk Sac Tumors in Children and Adolescents: A Retrospective Study from China

W. Dai, H. Liu, Y. Chen and Z. Chen
American Journal of Neuroradiology July 2022, 43 (7) 1054-1059; DOI: https://doi.org/10.3174/ajnr.A7556
W. Dai
aFrom the Department of Radiology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
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H. Liu
aFrom the Department of Radiology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
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Y. Chen
aFrom the Department of Radiology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
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  • ORCID record for Y. Chen
Z. Chen
aFrom the Department of Radiology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
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Article Figures & Data

Figures

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  • FIG 1.
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    FIG 1.

    A 4-year-old boy with a right cerebellar hemisphere YST. A, MR image shows the tumor located in the right cerebellar hemisphere. It is solid with cystic changes. B, There is a small amount of edema around the tumor, and the fourth ventricle is compressed. C, DWI shows isosignal of solid components of the mass. D, The tumor shows serpiginous enhancement.

  • FIG 2.
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    FIG 2.

    An 11-year-old boy with a pineal region YST. A, MR image shows the tumor located in the pineal region with a slightly low signal associated with supratentorial dilation of the ventricle. B, The T2 sequence shows multiple, fine cysts with hypersignal (arrows). C and D, The DWI sequence and ADC map show that the tumor signal is the same as that of the cerebral cortex.

  • FIG 3.
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    FIG 3.

    A boy, 2 years and 10 months of age, with a right cerebellar hemisphere YST. A, CT shows a slightly hypodense mass lesion accompanied by peritumoral edema. B, Enhanced CT shows heterogeneous density. C, H&E staining shows a typical Schiller-Duval body and loose, vacuolated network structures and prominent nucleoli with more atypia cells.

Tables

  • Figures
  • Clinical manifestations of 25 patients with primary, intracranial, pure YST

    No.SexAge (yr)Clinical Manifestations
    1Boy11Headache with vomiting
    2Boy4Gait instability
    3Boy2 and 10 moHeadache with vomiting
    4Boy1 and 10 moHeadache with vomiting
    5Boy10Headache with vomiting
    6Boy3Vomiting with convulsions
    7Boy11Headache with vomiting
    8Boy2.5Headache with vomiting and gait instability
    9Boy2Gait instability
    10Boy3Headache with vomiting and gait instability
    11Girl12Headache with vomiting
    12Boy13Headache with vomiting and gait instability
    13Boy2Gait instability
    14Girl10Headaches, sleepiness, and blurred vision
    15Boy9Headache with blurred vision
    16Boy10Headache with seizures
    17Boy14Side limb weakness
    18Boy14Headache with vomiting
    19Boy1 and 11 moHeadache with vomiting and gait instability
    20Girl10Headaches, sleepiness, and blurred vision
    21Boy5Headache with vomiting
    22Boy10Headache
    23Girl11Headache
    24Boy15Headache and vomiting with diplopia and precocious puberty
    25Boy17Headache with vomiting and gait instability
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American Journal of Neuroradiology: 43 (7)
American Journal of Neuroradiology
Vol. 43, Issue 7
1 Jul 2022
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Cite this article
W. Dai, H. Liu, Y. Chen, Z. Chen
Imaging Findings and Clinical Analysis of Primary Intracranial Pure Yolk Sac Tumors in Children and Adolescents: A Retrospective Study from China
American Journal of Neuroradiology Jul 2022, 43 (7) 1054-1059; DOI: 10.3174/ajnr.A7556

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Primary Intracranial Yolk Sac Tumors in Children
W. Dai, H. Liu, Y. Chen, Z. Chen
American Journal of Neuroradiology Jul 2022, 43 (7) 1054-1059; DOI: 10.3174/ajnr.A7556
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