Article Figures & Data
Figures
- FIG 1.
Quantitative measurement technique. Manual ROIs were drawn on representative images tracing the interface between the wall and lumen (luminal contour) and between the wall and surrounding tissues (outer wall contour). Total area of the vessel (area within the outer contour), luminal area (area within the inner contour), mean signal intensity, and SD were recorded for each patient. Sum indicates the sum of signal intensities within the selected region; Min, minimum; Max, maximum.
- FIG 2.
When we compare sagittal T1-SPACE precontrast (A) and sagittal T1-SPACE postcontrast (B), there are multiple focal enhancing lesions seen along the cortical surface (small arrows) on postcontrast IVW. On T1-DANTE-CAIPI-SPACE (C), the cortically based enhancing lesions disappear. The enhancing foci represent nonsuppression of blood signal in small cortical veins.
- FIG 3.
Sagittal T1-SPACE precontrast (A) shows a normal right M1 MCA segment without wall thickening. Sagittal T1-SPACE postcontrast (B) shows eccentric wall enhancement along the posterior, superior, and inferior walls of the M1 MCA (arrowhead) and the right V4 vertebral artery (short arrow) as well as nonsuppression of luminal signal in the right petrous ICA (long arrow) and the transverse sinus (thick arrow). Sagittal T1-DANTE-SPACE (C) shows the normal wall appearance of the right M1 MCA and V4 vertebral artery segments, similar to precontrast acquisition, and suppression of the venous signal.
Tables
3D T1-SPACE DANTE-CAIPI-T1-SPACE DANTE-T1-SPACE TR/TE (ms) 1000/11.0 1000/11.0 1000/11.0 In-plane resolution (mm) 0.56 × 0.56 0.56 × 0.56 0.56 × 0.56 Section thickness (mm) 0.56 0.56 0.56 Flip angle Variable Variable Variable FOV (mm) 180 × 180 180 × 180 180 × 180 Parallel imaging factor 2 2 2 Averages 1 1 1 Scan time (min) 8:08 5:11 8:47 DANTE No Yes Yes CAIPI No Yes No Characteristics Cohort Age (age group) (median) 22–80 years, median age, 53 years Sex (%) Male 34 (38.2%) Female 55 (61.8%) Clinical indication for IVW MR imaging Intracranial atherosclerotic disease 33 Aneurysm postcoiling/Pipeline stent/clipping 31 Vasculitis 11 Moyamoya disease/syndrome 3 Aneurysm 4 CADASIL 2 Radiation vasculopathy 1 Cryptogenic stroke 4 SPACE DANTE-CAIPI-SPACE P Value Qualitative measurements Image quality 2.5 (2–3) 2 (1.5–2.5) <.001 SNR 1.5 (1–2) 2 (2–2.5) <.001 Artifacts 3.5 (3–4) 3 (2–3) <.001 Art. blood suppression 3 (2.5–3.5) 1.25 (1–1.5) <.001 Lesion 2 (1.5–2.5) 1.5 (1–2) <.001 Ven. blood suppression 3 (2–3.375) 1.5 (1.125–2) <.001 Motion 1 (0–2) 0 (0–0.5) <.001 Quantitative measurement Lumen area (mm2) 7.9 (5.5–10.3) 7.6 (4.8–11.0) .45 Wall area (mm2) 12.6 (9.9–16.3) 12.4 (10.1–14.6) .04 Lumen CR 0.33 (0.26–0.43) 0.37 (0.27–0.48) .003 Wall lumen CR 2.3 (1.9–2.6) 1.9 (1.7–2.5) <.001 Note:—Art. indicates arterial; Ven., venous; CR, contrast ratio.
↵a Values are expressed as median (interquartile range).
SPACE DANTE-SPACE P Value Qualitative measurements Image quality 2.5 (2–3) 2 (1.5–2.5) <.001 SNR 2 (2–2.5) 2 (1.5–2.5) <.001 Artifacts 3.5 (3–4) 2.5 (2–3) <.001 Art. blood suppression 3 (2.625–3.5) 1.5 (1–1.875) <.001 Lesion 2.5 (2–3) 1.75 (1–2) <.001 Ven. blood suppression 3 (2–3) 2 (1.5–2) <.001 Motion 0.5 (0–2.75) 0.75 (0–2) .50 Quantitative measurement Lumen area (mm2) 5.9 (4.5–8.4) 6.8 (4.9–8.4) .66 Wall area (mm2) 14.4 (9.9–18.2) 14.1 (10.9–20.1) .09 Lumen CR 0.33 (0.26–0.55) 0.35 (0.26–0.53) .22 Wall lumen CR 2.2 (1.8–2.4) 2.2 (1.9–2.6) .46 Note:—Art. indicates arterial; Ven., venous; CR, contrast ratio.
↵a Values are expressed as median (interquartile range).
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