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Research ArticleAdult Brain

MTT Heterogeneity in Perfusion CT Imaging as a Predictor of Outcome after Aneurysmal SAH

B.B. Hofmann, I. Fischer, A. Engel, K. Jannusch, D.M. Donaldson, C. Karadag, J.H. van Lieshout, K. Beseoglu, S. Muhammad, B. Turowski, D. Hänggi, M.A. Kamp and C. Rubbert
American Journal of Neuroradiology August 2021, 42 (8) 1387-1395; DOI: https://doi.org/10.3174/ajnr.A7169
B.B. Hofmann
aFrom the Department of Neurosurgery (B.B.H., I.F., A.E., D.M.D., C.K., J.H.v.L., K.B., S.M., D.H., M.A.K.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany
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I. Fischer
aFrom the Department of Neurosurgery (B.B.H., I.F., A.E., D.M.D., C.K., J.H.v.L., K.B., S.M., D.H., M.A.K.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany
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A. Engel
aFrom the Department of Neurosurgery (B.B.H., I.F., A.E., D.M.D., C.K., J.H.v.L., K.B., S.M., D.H., M.A.K.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany
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K. Jannusch
bDepartment of Diagnostic and Interventional Radiology (K.J., B.T., C.R.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany.
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D.M. Donaldson
aFrom the Department of Neurosurgery (B.B.H., I.F., A.E., D.M.D., C.K., J.H.v.L., K.B., S.M., D.H., M.A.K.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany
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C. Karadag
cMedical Faculty (C.K.), University Düsseldorf, Düsseldorf, Germany
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J.H. van Lieshout
aFrom the Department of Neurosurgery (B.B.H., I.F., A.E., D.M.D., C.K., J.H.v.L., K.B., S.M., D.H., M.A.K.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany
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K. Beseoglu
aFrom the Department of Neurosurgery (B.B.H., I.F., A.E., D.M.D., C.K., J.H.v.L., K.B., S.M., D.H., M.A.K.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany
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S. Muhammad
aFrom the Department of Neurosurgery (B.B.H., I.F., A.E., D.M.D., C.K., J.H.v.L., K.B., S.M., D.H., M.A.K.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany
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B. Turowski
bDepartment of Diagnostic and Interventional Radiology (K.J., B.T., C.R.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany.
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D. Hänggi
aFrom the Department of Neurosurgery (B.B.H., I.F., A.E., D.M.D., C.K., J.H.v.L., K.B., S.M., D.H., M.A.K.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany
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M.A. Kamp
aFrom the Department of Neurosurgery (B.B.H., I.F., A.E., D.M.D., C.K., J.H.v.L., K.B., S.M., D.H., M.A.K.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany
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C. Rubbert
bDepartment of Diagnostic and Interventional Radiology (K.J., B.T., C.R.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany.
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Article Information

vol. 42 no. 8 1387-1395
DOI 
https://doi.org/10.3174/ajnr.A7169
PubMed 
34083263

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received January 22, 2021
  • Accepted after revision March 9, 2021
  • Published online August 11, 2021.

Article Versions

  • Latest version (June 3, 2021 - 06:51).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2021 by American Journal of Neuroradiology

Author Information

  1. B.B. Hofmanna,
  2. I. Fischera,
  3. A. Engela,
  4. K. Jannuschb,
  5. D.M. Donaldsona,
  6. C. Karadagc,
  7. J.H. van Lieshouta,
  8. K. Beseoglua,
  9. S. Muhammada,
  10. B. Turowskib,
  11. D. Hänggia,
  12. M.A. Kampa and
  13. C. Rubbertb
  1. aFrom the Department of Neurosurgery (B.B.H., I.F., A.E., D.M.D., C.K., J.H.v.L., K.B., S.M., D.H., M.A.K.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany
  2. bDepartment of Diagnostic and Interventional Radiology (K.J., B.T., C.R.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany.
  3. cMedical Faculty (C.K.), University Düsseldorf, Düsseldorf, Germany
  1. Please address correspondence to Björn B. Hofmann, MD, Departments of Neurosurgery, Medical Faculty, Heinrich-Heine-University University Düsseldorf, Medical Faculty, Department of Neurosurgery, Moorenstr 5, D40225 Düsseldorf, Germany; e-mail: bjoern.hofmann{at}med.uni-duesseldorf.de
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B.B. Hofmann, I. Fischer, A. Engel, K. Jannusch, D.M. Donaldson, C. Karadag, J.H. van Lieshout, K. Beseoglu, S. Muhammad, B. Turowski, D. Hänggi, M.A. Kamp, C. Rubbert
MTT Heterogeneity in Perfusion CT Imaging as a Predictor of Outcome after Aneurysmal SAH
American Journal of Neuroradiology Aug 2021, 42 (8) 1387-1395; DOI: 10.3174/ajnr.A7169

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MTT Heterogeneity in Perfusion CT Imaging as a Predictor of Outcome after Aneurysmal SAH
B.B. Hofmann, I. Fischer, A. Engel, K. Jannusch, D.M. Donaldson, C. Karadag, J.H. van Lieshout, K. Beseoglu, S. Muhammad, B. Turowski, D. Hänggi, M.A. Kamp, C. Rubbert
American Journal of Neuroradiology Aug 2021, 42 (8) 1387-1395; DOI: 10.3174/ajnr.A7169
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Blood Pressure Affects the Early CT Perfusion Imaging in Patients with aSAH Reflecting Early Disturbed Autoregulation
    Björn B. Hofmann, Daniel M. Donaldson, Igor Fischer, Cihat Karadag, Milad Neyazi, Guilherme S. Piedade, Yousef Abusabha, Sajjad Muhammad, Christian Rubbert, Daniel Hänggi, Kerim Beseoglu
    Neurocritical Care 2023 39 1
  • Clinical Outcome Prediction of Early Brain Injury in Aneurysmal Subarachnoid Hemorrhage: the SHELTER-Score
    Björn B. Hofmann, Daniel M. Donaldson, Milad Neyazi, Yousef Abusabha, Kerim Beseoglu, Daniel Hänggi, Jan F. Cornelius, Igor Fischer, Sajjad Muhammad
    Neurocritical Care 2024 40 2
  • Evaluation of MTT Heterogeneity of Perfusion CT Imaging in the Early Brain Injury Phase: An Insight into aSAH Pathopysiology
    Björn B. Hofmann, Igor Fischer, Daniel M. Donaldson, Yousef Abusabha, Cihat Karadag, Sajjad Muhammad, Kerim Beseoglu, Daniel Hänggi, Bernd Turowski, Christian Rubbert, Jan F. Cornelius, Marcel A. Kamp
    Brain Sciences 2023 13 5
  • Initial Temporal Muscle Thickness and Area: Poor Predictors of Neurological Outcome in Aneurysmal Subarachnoid Hemorrhage in a Central European Patient Cohort
    Cihat Karadag, Marcel A. Kamp, Igor Fischer, Hieronymus D. Boogaarts, Kerim Beseoglu, Sajjad Muhammad, Jan F. Cornelius, Björn B. Hofmann
    Journal of Clinical Medicine 2023 12 16
  • Evaluation of FRESH scores in predicting outcome and quality of life after aneurysmal subarachnoid haemorrhage in a European patient cohort
    Björn B. Hofmann, Evgenia P. Gundlach, Igor Fischer, Sajjad Muhammad, Rainer Kram, Kerim Beseoglu, Jan F. Cornelius
    Acta Neurochirurgica 2024 166 1
  • Effects of apolipoprotein E polymorphism on cerebral oxygen saturation, cerebral perfusion, and early prognosis after traumatic brain injury
    Xun Lin, Qilin Li, Xiaochuan Sun, Quanhong Shi, Wei Dan, Yan Zhan, Bo Deng, Yulong Xia, Yanfeng Xie, Li Jiang
    Annals of Clinical and Translational Neurology 2023 10 6
  • Neuroradiological diagnosis and therapy of cerebral vasospasm after subarachnoid hemorrhage
    Alexander Neumann, Hannes Schacht, Peter Schramm
    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 2024 196 11
  • Novel Insights into Pathophysiology of Delayed Cerebral Ischemia: Effects of Current Rescue Therapy on Microvascular Perfusion Heterogeneity
    Björn B. Hofmann, Cihat Karadag, Christian Rubbert, Simon Schieferdecker, Milad Neyazi, Yousef Abusabha, Igor Fischer, Hieronymus D. Boogaarts, Sajjad Muhammad, Kerim Beseoglu, Daniel Hänggi, Bernd Turowski, Marcel A. Kamp, Jan F. Cornelius
    Biomedicines 2023 11 10
  • CT perfusion imaging in aneurysmal subarachnoid hemorrhage. State of the art
    Valentina Elisabetta Lolli, Adrien Guenego, Niloufar Sadeghi, Lise Jodaitis, Boris Lubicz, Fabio Silvio Taccone, Elisa Gouvea Bogossian
    Frontiers in Radiology 2024 4
  • Cognitive outcomes after extracranial-intracranial bypass surgery in elderly patients diagnosed with atherosclerotic cerebral steno-occlusive artery disease
    Yu Duan, Jian Li, Xin Zhang, Shihong Li, Qiliang Chai, Yingying Zhang, Guohui Huang, Ziwei Xu, Zhuyu Li, Renling Mao, Dongwei Dai
    Frontiers in Aging Neuroscience 2025 17

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