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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleRadiology-Pathology Correlation

Calcified Pseudoneoplasm of the Neuraxis

J.C. Benson, J. Trejo-Lopez, J. Boland-Froemming, B. Pollock, C.H. Hunt and J.T. Wald
American Journal of Neuroradiology October 2021, 42 (10) 1751-1754; DOI: https://doi.org/10.3174/ajnr.A7237
J.C. Benson
aFrom the Department of Radiology (J.C.B., C.H.H., J.T.W.), Mayo Clinic, Rochester, Minnesota
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J. Trejo-Lopez
bDepartment of Laboratory Medicine and Pathology (J.T.-L., J.B.-F.), Mayo Clinic, Rochester, Minnesota
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J. Boland-Froemming
bDepartment of Laboratory Medicine and Pathology (J.T.-L., J.B.-F.), Mayo Clinic, Rochester, Minnesota
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B. Pollock
cDepartment of Neurologic Surgery (B.P.), Mayo Clinic, Rochester, Minnesota
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C.H. Hunt
aFrom the Department of Radiology (J.C.B., C.H.H., J.T.W.), Mayo Clinic, Rochester, Minnesota
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J.T. Wald
aFrom the Department of Radiology (J.C.B., C.H.H., J.T.W.), Mayo Clinic, Rochester, Minnesota
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  • FIG 1.
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    FIG 1.

    Initial CT scan of the mass obtained 15 years before presentation at our institution. The images demonstrate a densely calcified mass in the right posterior fossa (asterisk), without substantial local mass effect.

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    FIG 2.

    MR imaging at the time of presentation demonstrates a slight interval increase in the size of the mass. Dense intralesional calcifications are again observed, as evidenced by substantial signal drop-out on T2 (A) and susceptibility-weighted (B) images. Axial T1 image (C) shows areas of internal hyperintense signal. FLAIR image (D) shows adjacent vasogenic edema, with a mild associated mass effect on the fourth ventricle. Axial (E) and coronal (F) postcontrast images demonstrate intense peripheral enhancement around the perimeter of the lesion, as well as a possible dural tail (arrow).

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    FIG 3.

    Histologic examination revealed a tumefactive lesion characterized by exuberant calcification (A, original magnification ×50) around areas of chondromyxoid fibrillary matrix (B, original magnification ×20). Palisading spindle cells and a mild chronic inflammatory infiltrate are present on the periphery (C, original magnification ×200). All specimens are stained with hematoxylin-eosin.

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American Journal of Neuroradiology: 42 (10)
American Journal of Neuroradiology
Vol. 42, Issue 10
1 Oct 2021
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Cite this article
J.C. Benson, J. Trejo-Lopez, J. Boland-Froemming, B. Pollock, C.H. Hunt, J.T. Wald
Calcified Pseudoneoplasm of the Neuraxis
American Journal of Neuroradiology Oct 2021, 42 (10) 1751-1754; DOI: 10.3174/ajnr.A7237

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Calcified Pseudoneoplasm of the Neuraxis
J.C. Benson, J. Trejo-Lopez, J. Boland-Froemming, B. Pollock, C.H. Hunt, J.T. Wald
American Journal of Neuroradiology Oct 2021, 42 (10) 1751-1754; DOI: 10.3174/ajnr.A7237
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