Article Figures & Data
Figures
- Fig 1.
Patient flow diagram showing how patients were selected for the study and the reasons for exclusion. We excluded patients for the following reasons: 1) missing either their SWI or T2-FLAIR scan; 2) lesions <3 mm or infratentorial lesions that could not be identified on the SWI due to artifacts; 3) automated lesion masks not passing quality checks; and 4) diagnostic doubt by the end of the study follow-up. RRMS indicates relapsing-remitting multiple sclerosis.
- Fig 2.
Lesion appearance on axial T2-FLAIR (upper row) and the corresponding susceptibility-weighted (lower row) images in patients with Sjögren disease (A and C) and MS (B and D). The patient with Sjögren disease has no visible CVs or IRs on the SWI. The patient with MS has clearly visible IRs, which correspond to the lesion edges visible on the T2-FLAIR. CVs are also visible inside the lesions as hypointense dots or lines.
- Fig 3.
The location of lesions with central veins in the CIS and non-MS groups. Error bars represent standard error.
- Fig 4.
Summary of the incidence of lesions with CVs in the CIS and non-MS groups. A, The number of lesions with CVs (per patient) in the 2 groups. B, The percentage of lesions with CVs (per patient) in the 2 groups.
- Fig 5.
Summary of the incidence of lesions with iron rings in the CIS and non-MS groups. A, The number of lesions with iron rings (per patient) in the 2 groups. B, The location of lesions with iron rings in the CIS group.
Tables
Demographic and clinical data of the patients included in the study
CIS Group (n = 112) Non-MS Group (n = 35) Mean age (SD, range) (yr) 35.4 (7.9, 19–49) 41.7 (11.5, 20–67) Sex, female No. (%) 70 (70.5%) 23 (65.7%) Clinical diagnosis at the end of the study No. (%) MS = 94 (83.9%) (including CDMS = 42 [37.5%]) CIS = 18 (16.1%) Autoimmune disease = 13 (37.1%)Vascular disease = 8 (22.9%)Incidental findings = 1 (2.9%)Infectious disease = 1 (2.9%)Headache = 3 (8.6%)Other = 9 (25.7%) +/− OCBs No. (not performed) 80/21 (11) 2/15 (18) Median EDSS (range) 1.5 (0–4.5) NA Median WM lesion No. (range) 4 (1–31) 7 (1–31) Note:—EDSS indicates Expanded Disability Status Scale; NA, not available.
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