Article Figures & Data
Figures
- Fig 1.
Global properties of the structural connectome based on normalized values of number of fibers comparing patients with TGA at acute and post-recovery stages with healthy controls. The normalization was done by dividing the number of fibers by the sum of ROI surface or volume. Clustering coefficient, shortest path length, global efficiency and local efficiency metrics were compared between groups. For each TGA stage, the global network metrics did not significantly differ between patients with TGA and controls.
- Fig 2.
Altered structural connections in patients with TGA. A, Structural connectivity differences between controls and patients with TGA at acute phase. The gray lines mean significant decrease of connectivity in patients compared with controls. The red dots represent the location of ROIs and their size is proportional to the number of significant connections. A network of 113 ROIs and 114 connections had significantly decreased structural connectivity in patients with TGA (P < .05 NBS corrected, t-values ranging from 3.03–8.73). B, In this widespread network, the cortical and subcortical regions (nodes) with a number of significantly altered connections between patients and controls greater than 4 were mainly located in inferior and mesial temporal, cingulate, and frontal cortices.
Tables
Characteristics of patients
No. Sex Age Precipitating Event Hippocampal Lesions on DTI Trace Images at the Acute Stage of TGA Laterality Number Head Location Body Tail 1 F 73 No 0 0 0 0 0 2 F 70 Stressful event Bilateral 2 0 2 0 3 M 69 No Bilateral 2 1 0 1 4 F 76 Stressful event 0 1 1 0 0 5 F 56 No Right 1 1 0 0 6 F 61 Stressful event Bilateral 4 1 0 2 7 F 65 Physical activity 0 0 0 0 0 8 F 62 No 0 0 0 0 0 9 F 67 Stressful event 0 0 0 0 0 10 F 80 Stressful event Right 1 1 0 0 11 F 62 Stressful event 0 0 0 0 0 12 M 57 Physical activity Bilateral 3 0 2 1 13 F 40 Physical activity 0 0 0 0 0 14 M 69 No Bilateral 2 0 2 0 15 F 70 Stressful event Bilateral 3 2 0 1 16 M 43 Physical activity Bilateral 2 2 0 0 17 F 78 Physical activity Left 1 0 0 1 18 F 63 No Bilateral 2 0 0 2
