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Research ArticleAdult Brain

Presurgical Identification of Primary Central Nervous System Lymphoma with Normalized Time-Intensity Curve: A Pilot Study of a New Method to Analyze DSC-PWI

A. Pons-Escoda, A. Garcia-Ruiz, P. Naval-Baudin, M. Cos, N. Vidal, G. Plans, J. Bruna, R. Perez-Lopez and C. Majos
American Journal of Neuroradiology October 2020, 41 (10) 1816-1824; DOI: https://doi.org/10.3174/ajnr.A6761
A. Pons-Escoda
aRadiology Department (A.P.-E., P.N.-B., M.C., C.M.), Institut de Diagnòstic per la Imatge, Hospital Universitari de Bellvitge. L’Hospitalet de Llobregat, Barcelona, Spain
fNeurooncology Unit (A.P.-E., N.V., G.P., J.B., C.M.), Insitut Català d’Oncologia, Institut d’Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
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  • ORCID record for A. Pons-Escoda
A. Garcia-Ruiz
bRadiomics Group (A.G.-R., R.P.-L.), Vall d’Hebron Institut d’Oncologia, Barcelona, Spain
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P. Naval-Baudin
aRadiology Department (A.P.-E., P.N.-B., M.C., C.M.), Institut de Diagnòstic per la Imatge, Hospital Universitari de Bellvitge. L’Hospitalet de Llobregat, Barcelona, Spain
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M. Cos
aRadiology Department (A.P.-E., P.N.-B., M.C., C.M.), Institut de Diagnòstic per la Imatge, Hospital Universitari de Bellvitge. L’Hospitalet de Llobregat, Barcelona, Spain
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N. Vidal
cPathology Department (N.V.), Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
fNeurooncology Unit (A.P.-E., N.V., G.P., J.B., C.M.), Insitut Català d’Oncologia, Institut d’Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
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G. Plans
dNeurosurgery Department (G.P.), Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
fNeurooncology Unit (A.P.-E., N.V., G.P., J.B., C.M.), Insitut Català d’Oncologia, Institut d’Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
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J. Bruna
eNeurology Department (J.B.), Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
fNeurooncology Unit (A.P.-E., N.V., G.P., J.B., C.M.), Insitut Català d’Oncologia, Institut d’Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
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R. Perez-Lopez
bRadiomics Group (A.G.-R., R.P.-L.), Vall d’Hebron Institut d’Oncologia, Barcelona, Spain
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C. Majos
aRadiology Department (A.P.-E., P.N.-B., M.C., C.M.), Institut de Diagnòstic per la Imatge, Hospital Universitari de Bellvitge. L’Hospitalet de Llobregat, Barcelona, Spain
fNeurooncology Unit (A.P.-E., N.V., G.P., J.B., C.M.), Insitut Català d’Oncologia, Institut d’Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
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Article Information

vol. 41 no. 10 1816-1824
DOI 
https://doi.org/10.3174/ajnr.A6761
PubMed 
32943424

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received May 5, 2020
  • Accepted after revision July 3, 2020
  • Published online October 6, 2020.

Article Versions

  • Latest version (September 17, 2020 - 09:17).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2020 by American Journal of Neuroradiology

Author Information

  1. A. Pons-Escodaa,f,
  2. A. Garcia-Ruizb,
  3. P. Naval-Baudina,
  4. M. Cosa,
  5. N. Vidalc,f,
  6. G. Plansd,f,
  7. J. Brunae,f,
  8. R. Perez-Lopezb and
  9. C. Majosa,f
  1. aRadiology Department (A.P.-E., P.N.-B., M.C., C.M.), Institut de Diagnòstic per la Imatge, Hospital Universitari de Bellvitge. L’Hospitalet de Llobregat, Barcelona, Spain
  2. bRadiomics Group (A.G.-R., R.P.-L.), Vall d’Hebron Institut d’Oncologia, Barcelona, Spain
  3. cPathology Department (N.V.), Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
  4. dNeurosurgery Department (G.P.), Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
  5. eNeurology Department (J.B.), Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
  6. fNeurooncology Unit (A.P.-E., N.V., G.P., J.B., C.M.), Insitut Català d’Oncologia, Institut d’Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
  1. Please address correspondence to Albert Pons-Escoda, MD, Radiology Department, Institut de Diagnòstic per la Imatge (IDI), Hospital Universitari de Bellvitge. C/Feixa Llarga SN, L’Hospitalet de Llobregat, 08907, Barcelona, Spain; e-mail: albert.pons.idi{at}gencat.cat; @PonsEscoda
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A. Pons-Escoda, A. Garcia-Ruiz, P. Naval-Baudin, M. Cos, N. Vidal, G. Plans, J. Bruna, R. Perez-Lopez, C. Majos
Presurgical Identification of Primary Central Nervous System Lymphoma with Normalized Time-Intensity Curve: A Pilot Study of a New Method to Analyze DSC-PWI
American Journal of Neuroradiology Oct 2020, 41 (10) 1816-1824; DOI: 10.3174/ajnr.A6761

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Presurgical Identification of Primary Central Nervous System Lymphoma with Normalized Time-Intensity Curve: A Pilot Study of a New Method to Analyze DSC-PWI
A. Pons-Escoda, A. Garcia-Ruiz, P. Naval-Baudin, M. Cos, N. Vidal, G. Plans, J. Bruna, R. Perez-Lopez, C. Majos
American Journal of Neuroradiology Oct 2020, 41 (10) 1816-1824; DOI: 10.3174/ajnr.A6761
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Cited By...

  • Imaging of Lymphomas Involving the CNS: An Update-Review of the Full Spectrum of Disease with an Emphasis on the World Health Organization Classifications of CNS Tumors 2021 and Hematolymphoid Tumors 2022
  • Diffuse Large B-Cell Epstein-Barr Virus-Positive Primary CNS Lymphoma in Non-AIDS Patients: High Diagnostic Accuracy of DSC Perfusion Metrics
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Imaging of Lymphomas Involving the CNS: An Update-Review of the Full Spectrum of Disease with an Emphasis on the World Health Organization Classifications of CNS Tumors 2021 and Hematolymphoid Tumors 2022
    A. Pons-Escoda, P. Naval-Baudin, R. Velasco, N. Vidal, C. Majós
    American Journal of Neuroradiology 2023 44 4
  • Voxel-level analysis of normalized DSC-PWI time-intensity curves: a potential generalizable approach and its proof of concept in discriminating glioblastoma and metastasis
    Albert Pons-Escoda, Alonso Garcia-Ruiz, Pablo Naval-Baudin, Francesco Grussu, Juan Jose Sanchez Fernandez, Angels Camins Simo, Noemi Vidal Sarro, Alejandro Fernandez-Coello, Jordi Bruna, Monica Cos, Raquel Perez-Lopez, Carles Majos
    European Radiology 2022 32 6
  • Classifying primary central nervous system lymphoma from glioblastoma using deep learning and radiomics based machine learning approach - a systematic review and meta-analysis
    Amrita Guha, Jayant S. Goda, Archya Dasgupta, Abhishek Mahajan, Soutik Halder, Jeetendra Gawde, Sanjay Talole
    Frontiers in Oncology 2022 12
  • Dynamic-susceptibility-contrast perfusion-weighted-imaging (DSC-PWI) in brain tumors: a brief up-to-date overview for clinical neuroradiologists
    Albert Pons-Escoda, Marion Smits
    European Radiology 2023 33 11
  • Simultaneous quantification of perfusion, permeability, and leakage effects in brain gliomas using dynamic spin-and-gradient-echo echoplanar imaging MRI
    Francesco Sanvito, Catalina Raymond, Nicholas S. Cho, Jingwen Yao, Akifumi Hagiwara, Joey Orpilla, Linda M. Liau, Richard G. Everson, Phioanh L. Nghiemphu, Albert Lai, Robert Prins, Noriko Salamon, Timothy F. Cloughesy, Benjamin M. Ellingson
    European Radiology 2023 34 5
  • Diffuse Large B-Cell Epstein-Barr Virus–Positive Primary CNS Lymphoma in Non-AIDS Patients: High Diagnostic Accuracy of DSC Perfusion Metrics
    A. Pons-Escoda, A. García-Ruíz, P. Naval-Baudin, F. Grussu, M. Viveros, N. Vidal, J. Bruna, G. Plans, M. Cos, R. Perez-Lopez, C. Majós
    American Journal of Neuroradiology 2022 43 11
  • Improved performance of non-preloaded and high flip-angle dynamic susceptibility contrast perfusion-weighted imaging sequences in the presurgical differentiation of brain lymphoma and glioblastoma
    Feng Wang, Xiaofang Zhou, Ruiquan Chen, Jie Kang, Xinyi Yang, Jinzhu Lin, Fang Liu, Dairong Cao, Zhen Xing
    European Radiology 2023 33 12
  • Differentiating IDH-mutant astrocytomas and 1p19q-codeleted oligodendrogliomas using DSC-PWI: high performance through cerebral blood volume and percentage of signal recovery percentiles
    Albert Pons-Escoda, Alonso Garcia-Ruiz, Pablo Naval-Baudin, Ignacio Martinez-Zalacain, Josep Castell, Angels Camins, Noemi Vidal, Jordi Bruna, Monica Cos, Raquel Perez-Lopez, Laura Oleaga, Esther Warnert, Marion Smits, Carles Majos
    European Radiology 2024 34 8
  • An accessible deep learning tool for voxel-wise classification of brain malignancies from perfusion MRI
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    Cell Reports Medicine 2024 5 3
  • MR dynamic-susceptibility-contrast perfusion metrics in the presurgical discrimination of adult solitary intra-axial cerebellar tumors
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    European Radiology 2023 33 12

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