Article Figures & Data
Figures
- Fig 1.
Receiver operating curves for perfusion-weighted MR imaging and MET PET/CT parameters for the differentiation of recurrence and radiation injury in patients with high-grade gliomas.
- Fig 2.
Contrast-enhanced T1-weighted MR image (A) and a relative CBV map (B) and an MET PET/CT image (C) for a 41-year-old woman with recurrent glioblastoma. The lesion in the right frontal lobe (arrow) shows enhancement (A) and positive findings on both the rCBV map (B) and MET PET/CT image (C). The lesion localized in the left frontal lobe (chevron) might be a meningioma, which has been stable for several years.
- Fig 3.
Contrast-enhanced T1-weighted MR image (A) and relative CBV map (B) and MET PET/CT image (C) for a 44-year-old man with necrosis. The lesion in the right parietal lobe (arrow) shows enhancement (A) and negative findings on both the rCBV map (B) and the MET PET/CT image (C).
Tables
Final Diagnosis Visual Assessment Total Positive Equivocal Negative Recurrence 30 3 0 33 Radiation injury 4 3 2 9 Total 34 6 2 42 Final Diagnosis Visual Assessment Total Positive Equivocal Negative Recurrence 22 8 3 33 Radiation injury 2 1 6 9 Total 24 9 9 42 - Table 3:
Results of semiquantitative analysis of MET PET/CT and PWI parameters for the differentiation of recurrence from radiation injury in patients with HGGs
Final Diagnosis P Valuea Recurrence Radiation Injury SUVmax 5.10 ± 2.41 2.41 ± 1.67 .003 SUVmean 2.83 ± 1.27 1.39 ± 0.9 .003 TBRSUVmax 3.48 ± 1.17 1.96 ± 0.96 .003 rCBVmean 2.68 ± 1.14 1.33 ± 0.77 .004 ↵a All P values for discrimination between recurrence and radiation injury are significant.
- Table 4:
Comparison of patients with recurrence with patients with radiation injury, according to cutoff values for TBRSUVmax and rCBVmean
PET Recurrence PWI Radiation Injury PWI + − Total + − Total + 25 7 32 0 3 3 − 1 0 1 1 5 6 Total 26 7 33 1 8 9 Note:—+ indicates TBRSUVmax ≥ 1.85 or rCBVmean ≥ 1.83; −, TBRSUVmax < 1.85 or rCBVmean < 1.83.
