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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleNeurointervention

Placement of a Stent within a Flow Diverter Improves Aneurysm Occlusion Rates

O. Ocal, A. Peker, S. Balci and A. Arat
American Journal of Neuroradiology November 2019, 40 (11) 1932-1938; DOI: https://doi.org/10.3174/ajnr.A6237
O. Ocal
aFrom the Department of Radiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
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A. Peker
aFrom the Department of Radiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
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S. Balci
aFrom the Department of Radiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
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A. Arat
aFrom the Department of Radiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
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  • Fig 1.
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    Fig 1.

    A, Left ICA angiogram shows a supraclinoid aneurysm. B, Angiogram after the deployment of the flow diverter shows good apposition of the device at the neck of the aneurysm but slight malapposition at the proximal landing zone (arrow). C, TOF-MRA image 3 months after the procedure shows residual filling in the aneurysm. D, Follow-up angiogram obtained 6 months after the procedure shows complete occlusion of the aneurysm. A filling defect is noted where the flow diverter was malapposed.

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    Fig 2.

    A, Left ICA angiogram shows a supraclinoid aneurysm similar to the aneurysm of the patient in Fig 1. B, Angiogram after deployment of the flow diverter shows malapposition at the distal end of the device (arrow). C, Angiogram at the end of the procedure shows good apposition of the device and a stent inside the device. D, Contrast-enhanced coronal MR image 3 months after the procedure shows no residual filling. E, Follow-up angiogram obtained 6 months after the procedure shows complete occlusion of the aneurysm.

Tables

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    Table 1:

    Comparison of categoric clinical variables in monotherapy and stented groups

    Monotherapy Group (n = 35)Stented Group (n = 33)P
    No.%No.%
    Sex
        Male14401133.3.561
        Female21602266.7
    Prior thromboembolic event
        Negative3188.63297.357
        Positive411.413
    Smoking
        Negative2468.62781.8.267
        Positive1131.4618.2
    Hypertension
        Negative2468.62369.6.920
        Positive1131.41030.4
    Diabetes mellitus
        Negative3291.43297.614
        Positive38.613
    Hyperlipidemia
        Negative3394.23090.9.668
        Positive25.839.1
    Malignancy
        Negative3394.23090.9.668
        Positive25.839.1
    • View popup
    Table 2:

    Comparison of continuous clinical variables in monotherapy and stented groups

    VariableMonotherapy GroupStented GroupP
    MeanMedian (Range)MeanMedian (Range)
    Age49.0 ± 15.050 (12–86)51.0 ± 14.752 (22–84).561
    Weight73.7 ± 15.278 (41–101)68.7 ± 11.566 (47–96).115
    Platelet inhibition level (%)a79.8 ± 16.278 (44–100)78.7 ± 20.481 (33−100).925
    Aneurysm diameter (mm)9.1 ± 10.85.0 (2–56)14.8 ± 9.013 (3–40)<.001b
    • ↵a VerifyNow P2Y12 assay.

    • ↵b Statistical significance.

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    Table 3:

    Comparison of angiographic variables in monotherapy and stented groups

    Monotherapy GroupStented GroupP
    No.%No.%
    Aneurysm locationa
        Proximal3687.83497.1.281
        Distal512.212.9
    Aneurysm locationa
        Anterior3482.93291.4.326
        Posterior717.138.6
    Aneurysm morphology
        Saccular3278.02160.0.087
        Fusiform922.01440.0
    0- to 3-mo follow-up
        Total occlusion1961.32273.3.316
        Residual filling1238.7826.7
    3- to 6-mo follow-up
        Total occlusion2670.22884.8.147
        Residual filling1129.8515.2
    9- to 12-mo follow-up
        Total occlusion3073.23193.9.019b
        Residual filling1126.826.1
    >12-mo follow-up
        Total occlusion3482.93193.9.149
        Residual filling717.126.1
    • ↵a Please see the Materials and Methods section for the description of each of these variables.

    • ↵b Statistical significance.

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American Journal of Neuroradiology: 40 (11)
American Journal of Neuroradiology
Vol. 40, Issue 11
1 Nov 2019
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Cite this article
O. Ocal, A. Peker, S. Balci, A. Arat
Placement of a Stent within a Flow Diverter Improves Aneurysm Occlusion Rates
American Journal of Neuroradiology Nov 2019, 40 (11) 1932-1938; DOI: 10.3174/ajnr.A6237

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Placement of a Stent within a Flow Diverter Improves Aneurysm Occlusion Rates
O. Ocal, A. Peker, S. Balci, A. Arat
American Journal of Neuroradiology Nov 2019, 40 (11) 1932-1938; DOI: 10.3174/ajnr.A6237
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  • The Safety and Efficacy of Flow Diversion versus Conventional Endovascular Treatment for Intracranial Aneurysms: A Meta-analysis of Real-world Cohort Studies from the Past 10 Years
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