Article Figures & Data
Figures
- Fig 1.
Flow diagram for the literature-selection process.
- Fig 2.
Forest plots to show the pooled incidences of conventional MR imaging findings in patients with TDL: open ring or incomplete rim enhancement (A), closed ring or complete rim enhancement (B), T2 hypointense rim (C), absent or mild mass effect (D), and absent or mild perilesional edema (E). Numbers are estimates with 95% confidence intervals in parentheses.
- Fig 3.
Images obtained in a 44-year-old man with biopsy-proved TDL. T2-weighted (A) and FLAIR (B) images show a well-defined high-signal-intensity lesion in the left cerebral hemisphere with mild perilesional edema. C, Contrast-enhanced T1-weighted image shows open ring enhancement. DWI (D) and the corresponding ADC map (E) reveal high ADC within the lesion and peripheral restricted diffusion. F, DSC demonstrates low cerebral blood volume.
- Fig 4.
Coupled forest plots of the sensitivity and specificity of MR Imaging for the diagnosis of a TDL. Numbers are estimates with 95% confidence intervals in parentheses.
Tables
Characteristics of the eligible studies
Author (yr) Patients with TDL (No.) Male (No.) Female (No.) Mean Age (yr) Age Range (yr) Duration of Patient Recruitment Institution Altintas et al (2012)4 54 17 37 31.8 18–63 NA 5 Medical centers, Turkey Cha et al (2001)5 10 3 7 34.5 13–57 NA New York University Medical Center Hiremath et al (2017)6 14 10 4 37.5 NA 2011.1–2015.12 Sree Chitra Tirunal Institute for Medical Sciences and Technology, India Jain et al (2017)7 11 7 4 19.6 10–41 2014.8–2017.3 Sawai Man Singh Medical College, India Kilic et al (2013)8 25 8 17 29 15–56 1993.2–2011.6 Hacettepe University, Faculty of Medicine, Turkey Kim et al (2009)9 15 8 7 42 27–57 1998.12–2005.12 Seoul National University Hospital and Samsung Medical Center, Republic of Korea Kiriyama et al (2011)10 12 6 6 27 (Median) 17–64 1993.1–2009.6 Nara Medical University, Japan Kuan et al (2013)11 12 1 11 41.5 16–62 1985.1–2010.12 Taipei Veterans General Hospital, Taiwan Lu et al (2015)12 18 10 8 NA 22–66 2007.4–2012.5 Asan Medical Center, Republic of Korea Lucchinetti et al (2008)13 151 NA NA NA NA 1987.9–2005.8 Mayo Clinic and Georg–August University, Germany Mabray et al (2015)14 24 10 14 35.1 16–53 2002–2011 University of California at San Francisco Malhotra et al (2009)15 18 8 10 26 4–50 NA Chhatrapati Sahuji Maharaj Medical University and Sanjay Gandhi Post Graduate Institute of Medical Sciences, India Miron et al (2013)16 10 2 8 26.8 NA 2007.1–2007.12 Sheba Medical Center, Israel Qi et al (2015)17 14 9 5 24 (Median) 4–51 2004.1–2009.1 Beijing Tiantan Hospital, China Saini et al (2011)18 18 10 8 31.8 10–61 2001.1–2009.12 Sree Chitra Tirunal Institute for Medical Sciences and Technology, India Sánchez et al (2017)19 15 3 12 36 NA 2010.1–2017.2 Hospital Universitario de La Princesa, Spain Siri et al (2015)20 16 5 11 35.7 20–65 NA 10 Medical centers, France Toh et al (2012)21 8 2 6 37.3 23–51 NA National Yang–Ming University, Taiwan Yiu et al (2014)22 31 14 17 10.4 NA 2004.9–2009.12 23 Medical centers, Canada Note:—NA indicates not available.
Jump to section
Related Articles
Cited By...
- Tumefactive demyelinating lesions: A literature review of recent findings
- Differential Diagnosis of Tumor-like Brain Lesions
- Tumefactive Primary Central Nervous System Vasculitis: Imaging Findings of a Rare and Underrecognized Neuroinflammatory Disease
- Paraneoplastic recurrent tumefactive demyelination in a 62-year-old man with metastatic seminoma