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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleAdult Brain
Open Access

An Automated Statistical Technique for Counting Distinct Multiple Sclerosis Lesions

J.D. Dworkin, K.A. Linn, I. Oguz, G.M. Fleishman, R. Bakshi, G. Nair, P.A. Calabresi, R.G. Henry, J. Oh, N. Papinutto, D. Pelletier, W. Rooney, W. Stern, N.L. Sicotte, D.S. Reich and R.T. Shinohara the North American Imaging in Multiple Sclerosis Cooperative
American Journal of Neuroradiology April 2018, 39 (4) 626-633; DOI: https://doi.org/10.3174/ajnr.A5556
J.D. Dworkin
aFrom the Departments of Biostatistics, Epidemiology, and Informatics (J.D.D., K.A.L., R.T.S.)
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K.A. Linn
aFrom the Departments of Biostatistics, Epidemiology, and Informatics (J.D.D., K.A.L., R.T.S.)
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I. Oguz
bRadiology (I.O., G.M.F.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
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G.M. Fleishman
bRadiology (I.O., G.M.F.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
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R. Bakshi
cLaboratory for Neuroimaging Research (R.B.), Partners Multiple Sclerosis Center, Ann Romney Center for Neurologic Diseases
dDepartments of Neurology (R.B.)
eRadiology (R.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
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G. Nair
fTranslational Neuroradiology Section (G.N., D.S.R.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
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P.A. Calabresi
gDepartment of Neurology (P.A.C., J.O., D.S.R.), the Johns Hopkins University School of Medicine, Baltimore, Maryland
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R.G. Henry
hDepartment of Neurology (R.G.H., N.P., W.S.), University of California, San Francisco, San Francisco, California
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J. Oh
gDepartment of Neurology (P.A.C., J.O., D.S.R.), the Johns Hopkins University School of Medicine, Baltimore, Maryland
iKeenan Research Centre for Biomedical Science (J.O.), St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada
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N. Papinutto
hDepartment of Neurology (R.G.H., N.P., W.S.), University of California, San Francisco, San Francisco, California
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D. Pelletier
jDepartment of Neurology (D.P.), Keck School of Medicine, University of Southern California, Los Angeles, California
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W. Rooney
kAdvanced Imaging Research Center (W.R.), Oregon Health & Science University, Portland, Oregon
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W. Stern
hDepartment of Neurology (R.G.H., N.P., W.S.), University of California, San Francisco, San Francisco, California
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N.L. Sicotte
lDepartment of Neurology (N.L.S.), Cedars-Sinai Medical Center, Los Angeles, California. A complete list of the NAIMS participants is provided in the acknowledgment section.
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D.S. Reich
fTranslational Neuroradiology Section (G.N., D.S.R.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
gDepartment of Neurology (P.A.C., J.O., D.S.R.), the Johns Hopkins University School of Medicine, Baltimore, Maryland
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R.T. Shinohara
aFrom the Departments of Biostatistics, Epidemiology, and Informatics (J.D.D., K.A.L., R.T.S.)
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Article Information

vol. 39 no. 4 626-633
DOI 
https://doi.org/10.3174/ajnr.A5556
PubMed 
29472300

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received October 30, 2017
  • Accepted after revision December 10, 2017
  • Published online April 10, 2018.

Article Versions

  • Latest version (February 22, 2018 - 07:14).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2018 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. J.D. Dworkina,
  2. K.A. Linna,
  3. I. Oguzb,
  4. G.M. Fleishmanb,
  5. R. Bakshic,d,e,
  6. G. Nairf,
  7. P.A. Calabresig,
  8. R.G. Henryh,
  9. J. Ohg,i,
  10. N. Papinuttoh,
  11. D. Pelletierj,
  12. W. Rooneyk,
  13. W. Sternh,
  14. N.L. Sicottel,
  15. D.S. Reichf,g and
  16. R.T. Shinoharaa
  17. the North American Imaging in Multiple Sclerosis Cooperative
  1. aFrom the Departments of Biostatistics, Epidemiology, and Informatics (J.D.D., K.A.L., R.T.S.)
  2. bRadiology (I.O., G.M.F.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
  3. cLaboratory for Neuroimaging Research (R.B.), Partners Multiple Sclerosis Center, Ann Romney Center for Neurologic Diseases
  4. dDepartments of Neurology (R.B.)
  5. eRadiology (R.B.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
  6. fTranslational Neuroradiology Section (G.N., D.S.R.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
  7. gDepartment of Neurology (P.A.C., J.O., D.S.R.), the Johns Hopkins University School of Medicine, Baltimore, Maryland
  8. hDepartment of Neurology (R.G.H., N.P., W.S.), University of California, San Francisco, San Francisco, California
  9. iKeenan Research Centre for Biomedical Science (J.O.), St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada
  10. jDepartment of Neurology (D.P.), Keck School of Medicine, University of Southern California, Los Angeles, California
  11. kAdvanced Imaging Research Center (W.R.), Oregon Health & Science University, Portland, Oregon
  12. lDepartment of Neurology (N.L.S.), Cedars-Sinai Medical Center, Los Angeles, California. A complete list of the NAIMS participants is provided in the acknowledgment section.
  1. Please address correspondence to Jordan D. Dworkin, 218 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104; e-mail: jdwor{at}pennmedicine.upenn.edu; @jddwor
View Full Text

Funding

  • Race to Erase MS Foundation

  • National Institute of Neurological Disorders and Stroke

    Intramural Research Program; R01 NS085211; R01 NS094456; R21 NS093349

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Cite this article
J.D. Dworkin, K.A. Linn, I. Oguz, G.M. Fleishman, R. Bakshi, G. Nair, P.A. Calabresi, R.G. Henry, J. Oh, N. Papinutto, D. Pelletier, W. Rooney, W. Stern, N.L. Sicotte, D.S. Reich, R.T. Shinohara
An Automated Statistical Technique for Counting Distinct Multiple Sclerosis Lesions
American Journal of Neuroradiology Apr 2018, 39 (4) 626-633; DOI: 10.3174/ajnr.A5556

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An Automated Statistical Technique for Counting Distinct Multiple Sclerosis Lesions
J.D. Dworkin, K.A. Linn, I. Oguz, G.M. Fleishman, R. Bakshi, G. Nair, P.A. Calabresi, R.G. Henry, J. Oh, N. Papinutto, D. Pelletier, W. Rooney, W. Stern, N.L. Sicotte, D.S. Reich, R.T. Shinohara
American Journal of Neuroradiology Apr 2018, 39 (4) 626-633; DOI: 10.3174/ajnr.A5556
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