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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleAdult Brain
Open Access

Optimization of DARTEL Settings for the Detection of Alzheimer Disease

J. Komatsu, I. Matsunari, M. Samuraki, K. Shima, M. Noguchi-Shinohara, K. Sakai, T. Hamaguchi, K. Ono, H. Matsuda and M. Yamada
American Journal of Neuroradiology March 2018, 39 (3) 473-478; DOI: https://doi.org/10.3174/ajnr.A5509
J. Komatsu
aFrom the Department of Neurology and Neurobiology of Aging (J.K., M.S., K. Shima, M.N.-S., K. Sakai, T.H., K.O., M.Y.), Kanazawa University Graduate School of Medical Sciences, Takara-machi, Ishikawa, Japan
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I. Matsunari
bDepartment of Clinical Research (I.M.), Medical and Pharmacological Research Center Foundation, Hakui, Ishikawa, Japan
cDivision of Nuclear Medicine (I.M.), Department of Radiology, Saitama Medical University Hospital, Iruma-gun, Saitama, Japan
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M. Samuraki
aFrom the Department of Neurology and Neurobiology of Aging (J.K., M.S., K. Shima, M.N.-S., K. Sakai, T.H., K.O., M.Y.), Kanazawa University Graduate School of Medical Sciences, Takara-machi, Ishikawa, Japan
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K. Shima
aFrom the Department of Neurology and Neurobiology of Aging (J.K., M.S., K. Shima, M.N.-S., K. Sakai, T.H., K.O., M.Y.), Kanazawa University Graduate School of Medical Sciences, Takara-machi, Ishikawa, Japan
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M. Noguchi-Shinohara
aFrom the Department of Neurology and Neurobiology of Aging (J.K., M.S., K. Shima, M.N.-S., K. Sakai, T.H., K.O., M.Y.), Kanazawa University Graduate School of Medical Sciences, Takara-machi, Ishikawa, Japan
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K. Sakai
aFrom the Department of Neurology and Neurobiology of Aging (J.K., M.S., K. Shima, M.N.-S., K. Sakai, T.H., K.O., M.Y.), Kanazawa University Graduate School of Medical Sciences, Takara-machi, Ishikawa, Japan
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T. Hamaguchi
aFrom the Department of Neurology and Neurobiology of Aging (J.K., M.S., K. Shima, M.N.-S., K. Sakai, T.H., K.O., M.Y.), Kanazawa University Graduate School of Medical Sciences, Takara-machi, Ishikawa, Japan
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K. Ono
aFrom the Department of Neurology and Neurobiology of Aging (J.K., M.S., K. Shima, M.N.-S., K. Sakai, T.H., K.O., M.Y.), Kanazawa University Graduate School of Medical Sciences, Takara-machi, Ishikawa, Japan
dDepartment of Neurology (K.O.), Showa University School of Medicine, Tokyo, Japan
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H. Matsuda
eIntegrative Brain Imaging Center (H.M.), National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.
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M. Yamada
aFrom the Department of Neurology and Neurobiology of Aging (J.K., M.S., K. Shima, M.N.-S., K. Sakai, T.H., K.O., M.Y.), Kanazawa University Graduate School of Medical Sciences, Takara-machi, Ishikawa, Japan
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References

  1. 1.↵
    1. Hirata Y,
    2. Matsuda H,
    3. Nemoto K, et al
    . Voxel-based morphometry to discriminate early Alzheimer's disease from controls. Neurosci Lett 2005;382:269–74 doi:10.1016/j.neulet.2005.03.038 pmid:15925102
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Kawachi T,
    2. Ishii K,
    3. Sakamoto S, et al
    . Comparison of the diagnostic performance of FDG-PET and VBM-MRI in very mild Alzheimer's disease. Eur J Nucl Med Mol Imaging 2006;33:801–09 doi:10.1007/s00259-005-0050-x pmid:16550383
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Bookstein FL
    . “Voxel-based morphometry” should not be used with imperfectly registered images. Neuroimage 2001;14:1454–62 doi:10.1006/nimg.2001.0770 pmid:11707101
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Ashburner J
    . A fast diffeomorphic image registration algorithm. Neuroimage 2007;38:95–113 doi:10.1016/j.neuroimage.2007.07.007 pmid:17761438
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Matsuda H,
    2. Mizumura S,
    3. Nemoto K, et al
    . Automatic voxel-based morphometry of structural MRI by SPM8 plus diffeomorphic anatomic registration through exponentiated lie algebra improves the diagnosis of probable Alzheimer disease. AJNR Am J Neuroradiol 2012;33:1109–14 doi:10.3174/ajnr.A2935 pmid:22300935
    Abstract/FREE Full Text
  6. 6.↵
    1. Shima K,
    2. Matsunari I,
    3. Samuraki M, et al
    . Posterior cingulate atrophy and metabolic decline in early stage Alzheimer's disease. Neurobiol Aging 2012;33:2006–17 doi:10.1016/j.neurobiolaging.2011.07.009 pmid:21855172
    CrossRefPubMed
  7. 7.↵
    1. Chen WP,
    2. Samuraki M,
    3. Shima K, et al
    . Effect of an age-mismatched and sex-mismatched normal database on the diagnostic performance of 18F-FDG PET for Alzheimer's disease: the Ishikawa Brain Imaging Study. Nucl Med Commun 2011;32:1128–33 doi:10.1097/MNM.0b013e32834b43c2 pmid:21934543
    CrossRefPubMed
  8. 8.↵
    1. Samuraki M,
    2. Matsunari I,
    3. Chen WP, et al
    . Glucose metabolism and gray-matter concentration in apolipoprotein E ε4 positive normal subjects. Neurobiol Aging 2012;33:2321–23 doi:10.1016/j.neurobiolaging.2011.11.020 pmid:22188720
    CrossRefPubMed
  9. 9.↵
    1. McKhann G,
    2. Drachman D,
    3. Folstein M, et al
    . Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939–44 doi:10.1212/WNL.34.7.939 pmid:6610841
    Abstract/FREE Full Text
  10. 10.↵
    1. Hughes CP,
    2. Berg L,
    3. Danziger WL, et al
    . A new clinical scale for the staging of dementia. Br J Psychiatry 1982;140:566–72 doi:10.1192/bjp.140.6.566 pmid:7104545
    Abstract/FREE Full Text
  11. 11.↵
    1. Folstein MF,
    2. Folstein SE,
    3. McHugh PR
    . “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189–98 doi:10.1016/0022-3956(75)90026-6 pmid:1202204
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Matsuda H,
    2. Mizumura S,
    3. Nagao T, et al
    . Automated discrimination between very early Alzheimer disease and controls using an easy Z-score imaging system for multicenter brain perfusion single-photon emission tomography. AJNR Am J Neuroradiol 2007;28:731–36 pmid:17416830
    Abstract/FREE Full Text
  13. 13.↵
    1. Maldjian JA,
    2. Laurienti PJ,
    3. Kraft RA, et al
    . An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 2003;19:1233–39 doi:10.1016/S1053-8119(03)00169-1 pmid:12880848
    CrossRefPubMed
  14. 14.↵
    1. Jones DK,
    2. Symms MR,
    3. Cercignani M, et al
    . The effect of filter size on VBM analyses of DT-MRI data. Neuroimage 2005;26:546–54 doi:10.1016/j.neuroimage.2005.02.013 pmid:15907311
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Shen S,
    2. Sterr A
    . Is DARTEL-based voxel-based morphometry affected by width of smoothing kernel and group size? A study using simulated atrophy. J Magn Reson Imaging 2013;37:1468–75 doi:10.1002/jmri.23927 pmid:23172789
    CrossRefPubMed
  16. 16.↵
    1. Frisoni GB,
    2. Testa C,
    3. Zorzan A, et al
    . Detection of grey matter loss in mild Alzheimer's disease with voxel based morphometry. J Neurol Neurosurg Psychiatry 2002;73:657–64 doi:10.1136/jnnp.73.6.657 pmid:12438466
    Abstract/FREE Full Text
  17. 17.↵
    1. Matsunari I,
    2. Samuraki M,
    3. Chen WP, et al
    . Comparison of 18F-FDG PET and optimized voxel-based morphometry for detection of Alzheimer's disease: aging effect on diagnostic performance. J Nucl Med 2007;48:1961–70 doi:10.2967/jnumed.107.042820 pmid:18006622
    Abstract/FREE Full Text
  18. 18.↵
    1. Rasmusson DX,
    2. Brandt J,
    3. Steele C, et al
    . Accuracy of clinical diagnosis of Alzheimer disease and clinical features of patients with non-Alzheimer disease neuropathology. Alzheimer Dis Assoc Disord 1996;10:180–88 doi:10.1097/00002093-199601040-00002 pmid:8939276
    CrossRefPubMedWeb of Science
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American Journal of Neuroradiology: 39 (3)
American Journal of Neuroradiology
Vol. 39, Issue 3
1 Mar 2018
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J. Komatsu, I. Matsunari, M. Samuraki, K. Shima, M. Noguchi-Shinohara, K. Sakai, T. Hamaguchi, K. Ono, H. Matsuda, M. Yamada
Optimization of DARTEL Settings for the Detection of Alzheimer Disease
American Journal of Neuroradiology Mar 2018, 39 (3) 473-478; DOI: 10.3174/ajnr.A5509

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Optimization of DARTEL Settings for the Detection of Alzheimer Disease
J. Komatsu, I. Matsunari, M. Samuraki, K. Shima, M. Noguchi-Shinohara, K. Sakai, T. Hamaguchi, K. Ono, H. Matsuda, M. Yamada
American Journal of Neuroradiology Mar 2018, 39 (3) 473-478; DOI: 10.3174/ajnr.A5509
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