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Research ArticleHead and Neck Imaging
Open Access

Retrospective Review of Otic Capsule Contour and Thickness in Patients with Otosclerosis and Individuals with Normal Hearing on CT

N. Sanghan, T. Chansakul, E.D. Kozin, A.F. Juliano, H.D. Curtin and K.L. Reinshagen
American Journal of Neuroradiology December 2018, 39 (12) 2350-2355; DOI: https://doi.org/10.3174/ajnr.A5892
N. Sanghan
aFrom the Department of Radiology (N.S.), Prince of Songkla University, Hadyai, Songkhla, Thailand
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T. Chansakul
aFrom the Department of Radiology (N.S.), Prince of Songkla University, Hadyai, Songkhla, Thailand
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E.D. Kozin
aFrom the Department of Radiology (N.S.), Prince of Songkla University, Hadyai, Songkhla, Thailand
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A.F. Juliano
aFrom the Department of Radiology (N.S.), Prince of Songkla University, Hadyai, Songkhla, Thailand
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H.D. Curtin
aFrom the Department of Radiology (N.S.), Prince of Songkla University, Hadyai, Songkhla, Thailand
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K.L. Reinshagen
aFrom the Department of Radiology (N.S.), Prince of Songkla University, Hadyai, Songkhla, Thailand
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    Fig 1.

    Qualitative description of the otic capsule contour relative to an imaginary line drawn from the anterior margin of the oval window to the cochleariform process. A, Normal temporal bone with a concave contour. B, Lucent phase of fenestral and retrofenestral otosclerosis with a flattened contour. C, Sclerotic phase of fenestral otosclerosis with a bulging or convex contour.

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    Fig 2.

    Measurement of otic capsule thickness from the posterolateral margin of the cochlea at the junction between the basal and middle turns to the most convex contour. A, Axial images parallel to the plane of the lateral semicircular canal (LSCC) are created. B, The axial slice at the level of the cochleariform process and anterior margin of the oval window is chosen. C, Measurement from the posterolateral margin of the cochlea at the junction of the basal and middle turns to the apex of the convex contour of the otic capsule is performed.

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    Fig 3.

    Measurement of otic capsule thickness in a patient without a convex contour of the otic capsule. A, Axial images parallel to the plane of the lateral semicircular canal (LSCC) are created. B, The axial slice at the level of the cochleariform process and anterior margin of the oval window is chosen. The sulcus between the cochleariform process and the anterior margin of the oval window is shown (white dashed line). C, Measurement from the posterolateral margin of the cochlea at the junction of the basal and middle turns to the depth of the sulcus anterior to the oval window is performed.

Tables

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    Table 1:

    Characteristics of the study groups

    Patient CharacteristicsOtosclerosisNormal Hearing
    No. of Patients5854
    No. of Ears104108
    Sex
        Male (%)21 (36.2)14 (25.9)
        Female (%)37 (63.8)40 (74.1)
        P value.31
    Mean age (yr)49.738.5
    Age (SD) (yr)13.913.7
        P value<.001
    CT modalities
        MDCT (%)35 (60.3)44 (81.5)
        CBCT (%)23 (39.7)10 (18.5)
         P value.02
    Otosclerosis involvement (%)
        Fenestral only71 (68.3)–
        Fenestral and retrofenestral31 (29.8)–
        Isolated round window2 (1.9)–
    Otosclerosis phase of disease (%)
        Sclerotic disease25 (24.0)–
        Mixed sclerotic lucent disease34 (32.7)–
        Lucent disease45 (43.3)–
    • Note:—–indicates not applicable.

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    Table 2:

    Otic capsule contour

    ContourOtosclerosisNormal HearingTotal
    Bulging/convex71273
    Flattened/concave33106139
    Total104108212
    Two-tailed P value<.001
    • View popup
    Table 3:

    Otic capsule contour and thickness for diagnosis of otosclerosis

    Diagnostic PerformanceBulging/Convex ContouraOtic Capsule Thickness >2.3 mmb
    Sensitivity (%)68.396.2
    Specificity (%)98.1100
    Positive predictive value (%)97.3100
    Negative predictive value (%)76.396.4
    • ↵a Bulging/convex contour across an imaginary line between the anterior margin of the oval window and the cochleariform process.

    • ↵b Otic capsule thickness measured from the posterolateral margin of the cochlea closest to the middle ear (junction of the basal and middle turns) to the most convex contour.

    • View popup
    Table 4:

    Mean otic capsule thickness in millimeters (2 SDs)

    Study GroupsRadiologist 1Radiologist 2Overall
    Otosclerosis (n = 104)3.09 (0.92)3.06 (0.97)3.08 (0.93)
    Normal hearing (n = 108)1.87 (0.32)1.78 (0.33)1.82 (0.31)
    • View popup
    Table 5:

    Overall mean otic capsule thickness in millimeters (2 SDs) and percentage of patients with a bulging/convex contour by phase of otosclerosis

    Phase of OtosclerosisMean ThicknessBulging/Convex Contour (%)Flattened/Concave Contour (%)
    Sclerotic (n = 25)3.02 (0.82)64.036.0
    Mixed (n = 34)3.20 (1.08)70.629.4
    Lucent (n = 45)3.06 (0.82)68.931.1
    P value.26a.86b
    • ↵a P value calculated with a 1-way ANOVA test.

    • ↵b P value calculated with a 2 × 3 table χ2 test.

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American Journal of Neuroradiology: 39 (12)
American Journal of Neuroradiology
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1 Dec 2018
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N. Sanghan, T. Chansakul, E.D. Kozin, A.F. Juliano, H.D. Curtin, K.L. Reinshagen
Retrospective Review of Otic Capsule Contour and Thickness in Patients with Otosclerosis and Individuals with Normal Hearing on CT
American Journal of Neuroradiology Dec 2018, 39 (12) 2350-2355; DOI: 10.3174/ajnr.A5892

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Retrospective Review of Otic Capsule Contour and Thickness in Patients with Otosclerosis and Individuals with Normal Hearing on CT
N. Sanghan, T. Chansakul, E.D. Kozin, A.F. Juliano, H.D. Curtin, K.L. Reinshagen
American Journal of Neuroradiology Dec 2018, 39 (12) 2350-2355; DOI: 10.3174/ajnr.A5892
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