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Research ArticlePediatric Neuroimaging

Hindbrain Herniation in Chiari II Malformation on Fetal and Postnatal MRI

U.D. Nagaraj, K.S. Bierbrauer, B. Zhang, J.L. Peiro and B.M. Kline-Fath
American Journal of Neuroradiology May 2017, 38 (5) 1031-1036; DOI: https://doi.org/10.3174/ajnr.A5116
U.D. Nagaraj
eUniversity of Cincinnati College of Medicine (U.D.N., K.S.B., B.Z., J.L.P., B.M.K.-F.), Cincinnati, Ohio.
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K.S. Bierbrauer
bDepartment of Pediatric Neurosurgery (K.S.B.)
eUniversity of Cincinnati College of Medicine (U.D.N., K.S.B., B.Z., J.L.P., B.M.K.-F.), Cincinnati, Ohio.
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B. Zhang
aFrom the Department of Radiology and Medical Imaging (B.Z., B.M.K.-F.)
cDivision of Biostatistics and Epidemiology (B.Z.)
eUniversity of Cincinnati College of Medicine (U.D.N., K.S.B., B.Z., J.L.P., B.M.K.-F.), Cincinnati, Ohio.
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J.L. Peiro
dDepartment of Pediatric Surgery (J.L.P.), Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
eUniversity of Cincinnati College of Medicine (U.D.N., K.S.B., B.Z., J.L.P., B.M.K.-F.), Cincinnati, Ohio.
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B.M. Kline-Fath
aFrom the Department of Radiology and Medical Imaging (B.Z., B.M.K.-F.)
eUniversity of Cincinnati College of Medicine (U.D.N., K.S.B., B.Z., J.L.P., B.M.K.-F.), Cincinnati, Ohio.
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REFERENCES

  1. 1.↵
    1. Adzick NS,
    2. Thom EA,
    3. Spong CY, et al
    . A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med 2011;364:993–1004 doi:10.1056/NEJMoa1014379 pmid:21306277
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Sutton LN,
    2. Adzick NS,
    3. Bilaniuk LT, et al
    . Improvement in hindbrain herniation demonstrated by serial fetal magnetic resonance imaging following fetal surgery for myelomeningocele. JAMA 1999;282:1826–31 doi:10.1001/jama.282.19.1826 pmid:10573273
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Wolpert M,
    2. Anderson M,
    3. Scott RM, et al
    . Chiari II malformation: MR imaging evaluation. AJR Am J Roentgenol 1987;149:1033–42 doi:10.2214/ajr.149.5.1033 pmid:3499774
    CrossRefPubMed
  4. 4.↵
    1. el Gammal T,
    2. Mark EK,
    3. Brooks BS
    . MR imaging malformation of Chiari II. AJR Am J Roentgenol 1988;150:163–70 doi:10.2214/ajr.150.1.163 pmid:3257116
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Geerdink N,
    2. van der Vliet T,
    3. Rotteveel JJ, et al
    . Interobserver reliability and diagnostic performance of Chiari II malformation measures in MR imaging, part 2. Childs Nerv Syst 2012;28:987–95 doi:10.1007/s00381-012-1763-3 pmid:22562191
    CrossRefPubMed
  6. 6.↵
    1. Glenn OA,
    2. Barkovich J
    . Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis, part 2. AJNR Am J Neuroradiol 2006;27:1807–14 pmid:17032846
    Abstract/FREE Full Text
  7. 7.↵
    1. Glenn OA
    . MR imaging of the fetal brain. Pediatr Radiol 2010;40:68–81 doi:10.1007/s00247-009-1459-3 pmid:19937234
    CrossRefPubMed
  8. 8.↵
    1. Righini A,
    2. Zirpoli S,
    3. Mrakic F, et al
    . Early prenatal MR imaging diagnosis of polymicrogyria. AJNR Am J Neuroradiol 2004;25:343–46 pmid:14970044
    Abstract/FREE Full Text
  9. 9.↵
    1. Mignone Philpott C,
    2. Shannon P,
    3. Chitayat D, et al
    . Diffusion-weighted imaging of the cerebellum in the fetus with Chiari II malformation. AJNR Am J Neuroradiol 2013;34:1656–60 doi:10.3174/ajnr.A3468 pmid:23721901
    Abstract/FREE Full Text
  10. 10.↵
    1. Batty R,
    2. Vitta L,
    3. Whitby EH, et al
    . Is there a causal relationship between open spinal dysraphism and Chiari II deformity? A study using in utero magnetic resonance imaging of the fetus. Neurosurgery 2012;70:890–98; discussion 898–99 doi:10.1227/NEU.0b013e318237a6c1 pmid:21946507
    CrossRefPubMed
  11. 11.↵
    1. Papadias A,
    2. Miller C,
    3. Martin WL, et al
    . Comparison of prenatal and postnatal MRI findings in the evaluation of intrauterine CNS anomalies requiring postnatal neurosurgical treatment. Childs Nerv Syst 2008;24:185–92 doi:10.1007/s00381-007-0452-0 pmid:17710413
    CrossRefPubMed
  12. 12.↵
    1. Adzick NS
    . Fetal surgery for spina bifida: past, present, future. Semin Pediatr Surg 2013;22:10–17 doi:10.1053/j.sempedsurg.2012.10.003 pmid:23395140
    CrossRefPubMed
  13. 13.↵
    1. Tortori-Donati P,
    2. Rossi A,
    3. Cama A
    . Spinal dysraphism: a review of neuroradiological features with embryological correlations and proposal for a new classification. Neuroradiology 2000;42:471–91 doi:10.1007/s002340000325 pmid:10952179
    CrossRefPubMedWeb of Science
  14. 14.↵
    1. Melchiorre K,
    2. Bhide A,
    3. Gika AD, et al
    . Counseling in isolated mild fetal ventriculomegaly. Ultrasound Obstet Gynecol 2009;34:212–24 doi:10.1002/uog.7307 pmid:19644944
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Sari A,
    2. Ahmetoglu A,
    3. Dinc H, et al
    . Fetal biometry: size and configuration of the third ventricle. Acta Radiol 2005;46:631–35 doi:10.1080/02841850510021715 pmid:16334847
    CrossRefPubMed
  16. 16.↵
    1. Magann EF,
    2. Sandlin AT,
    3. Ounpraseuth ST
    . Amniotic fluid and the clinical relevance of the sonographically estimated amniotic fluid volume: oligohydramnios. J Ultrasound Med 2011;30:1573–85 doi:10.7863/jum.2011.30.11.1573 pmid:22039031
    Abstract/FREE Full Text
  17. 17.↵
    1. Sandlin AT,
    2. Chauhan SP,
    3. Magann EF
    . Clinical relevance of sonographically estimated amniotic fluid volume: polyhydramnios. J Ultrasound Med 2013;32:851–63 doi:10.7863/ultra.32.5.851 pmid:23620328
    Abstract/FREE Full Text
  18. 18.↵
    1. Coleman BG,
    2. Langer JE,
    3. Horii SC
    . The diagnostic features of spina bifida: the role of ultrasound. Fetal Diagn Ther 2015;37:179–96 doi:10.1159/000364806 pmid:25341807
    CrossRefPubMed
  19. 19.↵
    1. Moldenhauer JS,
    2. Soni S,
    3. Rintoul NE, et al
    . Fetal myelomeningocele repair: the post-MOMS experience at the Children's Hospital of Philadelphia. Fetal Diagn Ther 2015;37:235–40 doi:10.1159/000365353 pmid:25138132
    CrossRefPubMed
  20. 20.↵
    1. Faria TC,
    2. Cavalheiro S,
    3. Hisaba WJ, et al
    . Improvement of motor function and decreased need for postnatal shunting in children who had undergone intrauterine myelomeningocele repair. Arq Neuropsiquiatr 2013;71:604–08 doi:10.1590/0004-282X20130104 pmid:24141440
    CrossRefPubMed
  21. 21.↵
    1. Hisaba WJ,
    2. Cavalheiro S,
    3. Almodim CG, et al
    . Intrauterine myelomeningocele repair postnatal results and follow-up at 3.5 years of age: initial experience from a single reference service in Brazil. Childs Nerv Syst 2012;28:461–67 doi:10.1007/s00381-011-1662-z pmid:22205531
    CrossRefPubMed
  22. 22.↵
    1. McLone DG,
    2. Dias MS
    . The Chiari II malformation: cause and impact. Childs Nerv Syst 2003;19:540–50 doi:10.1007/s00381-003-0792-3 pmid:12920543
    CrossRefPubMedWeb of Science
  23. 23.↵
    1. McLone DG,
    2. Knepper PA
    . The cause of Chiari II malformation: a unified theory. Pediatr Neurosci 1989;15:1–12 doi:10.1159/000120432 pmid:2699756
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. Tulipan N,
    2. Wellons JC 3rd.,
    3. Thom EA, et al
    ; MOMS Investigators. Prenatal surgery for myelomeningocele and the need for cerebrospinal fluid shunt placement. J Neurosurg Pediatr 2015;16:613–20 doi:10.3171/2015.7.PEDS15336 pmid:26369371
    CrossRefPubMed
  25. 25.↵
    1. Almog B,
    2. Gamzu R,
    3. Achiron R, et al
    . Fetal lateral ventricular width: what should be its upper limit? A prospective cohort study and reanalysis of the current and previous data. J Ultrasound Med 2003;22:39–43 doi:10.7863/jum.2003.22.1.39 pmid:12523609
    Abstract/FREE Full Text
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American Journal of Neuroradiology: 38 (5)
American Journal of Neuroradiology
Vol. 38, Issue 5
1 May 2017
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U.D. Nagaraj, K.S. Bierbrauer, B. Zhang, J.L. Peiro, B.M. Kline-Fath
Hindbrain Herniation in Chiari II Malformation on Fetal and Postnatal MRI
American Journal of Neuroradiology May 2017, 38 (5) 1031-1036; DOI: 10.3174/ajnr.A5116

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Hindbrain Herniation in Chiari II Malformation on Fetal and Postnatal MRI
U.D. Nagaraj, K.S. Bierbrauer, B. Zhang, J.L. Peiro, B.M. Kline-Fath
American Journal of Neuroradiology May 2017, 38 (5) 1031-1036; DOI: 10.3174/ajnr.A5116
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  • Chiari II brain malformation is secondary to open spina bifida
  • Morphometric Analysis of Spina Bifida after Fetal Repair Shows New Subtypes with Associated Outcomes
  • The Perplexity Surrounding Chiari Malformations - Are We Any Wiser Now?
  • Fetal Intraventricular Hemorrhage in Open Neural Tube Defects: Prenatal Imaging Evaluation and Perinatal Outcomes
  • Reliability of MR Imaging-Based Posterior Fossa and Brain Stem Measurements in Open Spinal Dysraphism in the Era of Fetal Surgery
  • Spinal Imaging Findings of Open Spinal Dysraphisms on Fetal and Postnatal MRI
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  • Clinical SVR of Fetal Brain MRI
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