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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Review ArticleExtracranial Vascular
Open Access

Imaging Carotid Atherosclerosis Plaque Ulceration: Comparison of Advanced Imaging Modalities and Recent Developments

J. Yuan, A. Usman, T. Das, A.J. Patterson, J.H. Gillard and M.J. Graves
American Journal of Neuroradiology April 2017, 38 (4) 664-671; DOI: https://doi.org/10.3174/ajnr.A5026
J. Yuan
aFrom the Department of Radiology (J.Y., A.U., J.H.G., M.J.G.), University of Cambridge, Cambridge, UK
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A. Usman
aFrom the Department of Radiology (J.Y., A.U., J.H.G., M.J.G.), University of Cambridge, Cambridge, UK
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T. Das
bDepartment of Radiology (T.D., A.J.P., M.J.G.), Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, UK.
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A.J. Patterson
bDepartment of Radiology (T.D., A.J.P., M.J.G.), Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, UK.
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J.H. Gillard
aFrom the Department of Radiology (J.Y., A.U., J.H.G., M.J.G.), University of Cambridge, Cambridge, UK
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M.J. Graves
aFrom the Department of Radiology (J.Y., A.U., J.H.G., M.J.G.), University of Cambridge, Cambridge, UK
bDepartment of Radiology (T.D., A.J.P., M.J.G.), Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, UK.
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Abstract

SUMMARY: Atherosclerosis remains the leading cause of long-term mortality and morbidity worldwide, despite remarkable advancement in its management. Vulnerable atherosclerotic plaques are principally responsible for thromboembolic events in various arterial territories such as carotid, coronary, and lower limb vessels. Carotid plaque ulceration is one of the key features associated with plaque vulnerability and is considered a notable indicator of previous plaque rupture and possible future cerebrovascular events. Multiple imaging modalities have been used to assess the degree of carotid plaque ulceration for diagnostic and research purposes. Early diagnosis and management of carotid artery disease could prevent further cerebrovascular events. In this review, we highlight the merits and limitations of various imaging techniques for identifying plaque ulceration.

ABBREVIATIONS:

CE-MRA
contrast-enhanced MRA
CDUS
color Doppler ultrasound
CEUS
contrast-enhanced ultrasound
US
ultrasound
XRA
x-ray contrast angiography
  • © 2017 by American Journal of Neuroradiology

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American Journal of Neuroradiology: 38 (4)
American Journal of Neuroradiology
Vol. 38, Issue 4
1 Apr 2017
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Cite this article
J. Yuan, A. Usman, T. Das, A.J. Patterson, J.H. Gillard, M.J. Graves
Imaging Carotid Atherosclerosis Plaque Ulceration: Comparison of Advanced Imaging Modalities and Recent Developments
American Journal of Neuroradiology Apr 2017, 38 (4) 664-671; DOI: 10.3174/ajnr.A5026

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Imaging Carotid Atherosclerosis Plaque Ulceration: Comparison of Advanced Imaging Modalities and Recent Developments
J. Yuan, A. Usman, T. Das, A.J. Patterson, J.H. Gillard, M.J. Graves
American Journal of Neuroradiology Apr 2017, 38 (4) 664-671; DOI: 10.3174/ajnr.A5026
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  • Reassessing the Carotid Artery Plaque "Rim Sign" on CTA: A New Analysis with Histopathologic Confirmation
  • Plaque Contact Surface Area and Flow Lumen Volume Predict Stroke Risk in Extracranial Carotid Artery Stenosis
  • 3D Ultrasound for Imaging and Quantifying Carotid Ulcers
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