Article Figures & Data
Figures
- Fig 1.
ROIs in infratentorial (A), posterior periatrial (B), corpus callosum (C), and juxtacortical (D) lesional tissues on postcontrast T2-weighted images. Note ROIs in normal-appearing white matter locations (E–I) on fractional anisotropy maps.
- Fig 2.
Baseline DTI characteristics of normal-appearing white matter, non-black holes, black holes, and gadolinium-enhancing lesions for radial diffusivity (A), axial diffusivity (B), fractional anisotropy (C), and mean diffusivity (D). Boxplots show median (dark line), upper and lower quartiles (box), maximum and minimum values excluding outliers (whiskers), and outliers (circles).
- Fig 3.
Longitudinal evolution of DTI metrics during 4 years for, non-black holes, black holes, and gadolinium-enhancing lesions for radial diffusivity (A), axial diffusivity (B), fractional anisotropy (C), and mean diffusivity (D). Mean values (symbol) and 95% confidence intervals (error bars) are presented. Statistical significance and effect from the mixed-model effect are presented in boxes.
Tables
Change/Month 95% CI % Annualized Change P Value NAWM RD × 10−6 mm2/s 0.2193 −0.187 to 0.625 0.57% .2898 AD × 10−6 mm2/s −0.2109 −0.614 to 0.192 −0.21% .3052 FA × 10−3 −0.2572 −0.551 to 0.037 −0.57% .0865 MD × 10−6 mm2/s 0.03209 −0.331 to 0.396 0.05% .8626 GAD RD × 10−6 mm2/s 0.6107 0.039 to 1.285 1.22% .0374 AD × 10−6 mm2/s 1.8831 1.135 to 2.631 2.25% <.0001a FA × 10−3 0.5074 0.031 to 0.984 2.10% .037 MD × 10−6 mm2/s 1.2788 0.695 to 1.863 2.00% <.0001a ↵a P < .05.
Change/Month 95% CI % Annualized Change P Value All T2 lesions RD × 10−6 mm2/s 0.05683 −0.181 to 0.295 0.11% .6401 AD × 10−6 mm2/s 0.5411 0.251 to 0.831 0.62% .0003a FA × 10−3 0.163 0.001 to 0.324 0.61% .0482a MD ×10−6 mm2/s 0.2695 0.040 to 0.499 0.41% .0211a BH RD × 10−6 mm2/s 0.3392 −0.028 to 0.706 0.57% .0701 AD × 10−6 mm2/s 0.1967 −0.200 to 0.593 0.22% .331 FA × 10−3 −0.2137 −0.422 to −0.005 −0.91% .0444 MD × 10−6 mm2/s 0.2919 −0.059 to 0.643 0.42% .1026 NBH RD ×10−6 mm2/s −0.4137 −0.967 to 0.140 −0.85% .1432 AD × 10−6 mm2/s −0.2392 −0.838 to 0.360 −0.28% .434 FA × 10−3 0.2907 −0.025 to 0.606 0.99% .0708 MD × 10−6 mm2/s −0.355 −0.174 to 0.884 −0.58% .1883 ↵a P < .05.
