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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleHead and Neck Imaging

Ultrasound of the Hypoglossal Nerve in the Neck: Visualization and Initial Clinical Experience with Patients

S. Meng, L.F. Reissig, C.-H. Tzou, K. Meng, W. Grisold and W. Weninger
American Journal of Neuroradiology February 2016, 37 (2) 354-359; DOI: https://doi.org/10.3174/ajnr.A4494
S. Meng
aFrom the Departments of Radiology (S.M.)
dCenter for Anatomy and Cell Biology (S.M., L.F.R., W.W.)
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L.F. Reissig
dCenter for Anatomy and Cell Biology (S.M., L.F.R., W.W.)
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C.-H. Tzou
eDivision of Plastic and Reconstructive Surgery (C.-H.T.), Department of Surgery, Medical University of Vienna, Vienna, Austria.
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K. Meng
bEar, Nose, and Throat Diseases (K.M.)
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W. Grisold
cNeurology (W.G.), KFJ Hospital, Vienna, Austria
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W. Weninger
dCenter for Anatomy and Cell Biology (S.M., L.F.R., W.W.)
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  • Fig 1.
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    Fig 1.

    Illustration of the hypoglossal nerve with exemplary US scans of the hypoglossal nerve of a healthy volunteer. A, Transversal scan at the floor of the mouth in a coronal body plane. B, Transversal scan at the posterior rim of the hyoglossal muscle in a coronal body plane. C, Transversal scan in a paracoronal body plane at the crossing of the nerve with the external carotid artery. D, Longitudinal scan at the carotid space in a paracoronal body plane. 1 = hypoglossal nerve, 2 = hyoglossal muscle, 3 = mylohyoid muscle, 4, = stylohyoid and styloglossal muscles, 5 = parotid gland, 6 = external carotid artery.

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    Fig 2.

    Dissection situs of the right side of a neck. View from ventrolateral. Note the exposed hypoglossal nerve (arrowheads) with dark ink markings along its course. Cr indicates cranial; cd, caudal; r, right; l, left.

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    Fig 3.

    Parasagittal US scan at the floor of the mouth of patient 1 (Table 2). Note the hypoglossal nerve entering the region with extensive scar tissue after a neck dissection operation. Inset: position of the US transducer; 1 = hypoglossal nerve, asterisks = body of the tongue, arrowheads = scar tissue.

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    Fig 4.

    Parasagittal US scan at the floor of the mouth of patient 2 (Table 2). The hypoglossal nerve is directly infiltrated by a squamous cell carcinoma of the tongue base. Inset: position of the US transducer; 1 = hypoglossal nerve, 2 = submandibular gland, asterisks = body of the tongue, arrowheads = squamous cell carcinoma of the tongue base.

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    Fig 5.

    Parasagittal US scan at the carotid space of patient 3 (Table 2). Anterior to the carotid space the hypoglossal nerve is thickened focally after a facial nerve end-to-side coaptation. Inset: position of the US transducer; 1 = hypoglossal nerve, 2 = submandibular gland, asterisk = body of the tongue, arrowheads = coaptation site.

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    Fig 6.

    Parasagittal US scan at the carotid space of patient 6 (Table 2). The hypoglossal nerve is thickened markedly in the carotid space due to formation of a fibroma. Inset: position of the US transducer; 1 = hypoglossal nerve, 2 = submandibular gland, asterisk = body of the tongue, arrowheads = fibroma.

Tables

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    Table 1:

    Summary of US scan measurements of volunteer hypoglossal nerve cross-sectional areas

    Right Side (Mean) (Median, SD, Maximum, Minimum)Left Side (Mean) (Median, SD, Maximum, Minimum)
    Location 1
        At the posterolateral rim of the mylohyoid muscle (mm2)1.9 (2, 0.6, 3, 0.8)1.9 (2, 0.6, 4, 1)
    Location 2
        At the crossing of the hypoglossal nerve with the external carotid artery (mm2)2.1 (1.7, 0.6, 3, 0.8)2.1 (2.1, 0.5, 3.4, 1.1)
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    Table 2:

    Summary of patient histories and US findings

    No.Age (yr)SexHistoryClinical Details on ReferralUS findings
    150MSquamous cell carcinoma of the tonsil, neck dissectionHypoglossal nerve palsyScar tissue around the nerve (Fig 3)
    272MSquamous cell carcinoma of the tongue baseHypoglossal nerve palsyTumor infiltration of the nerve (Fig 4)
    333FFacial nerve end-to-side coaptation to the hypoglossal nerve after tongue palsy after cerebellopontine angle tumor resectionTongue paresisNerve coaptation site with focal hypoglossal nerve thickening (Fig 5)
    468FPartial hypoglossal nerve transfer for facial nerve reconstruction after malignant parotid gland tumor resectionTongue weaknessNerve transfer site with focal thickening and fibrosis
    548MSquamous cell carcinoma of the tonsil, neck dissection, radiotherapy, chemotherapyHypoglossal palsyScar tissue entrapment of the hypoglossal nerve
    655MNeurofibromatosisScreeningNeurofibroma (Fig 6)
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American Journal of Neuroradiology: 37 (2)
American Journal of Neuroradiology
Vol. 37, Issue 2
1 Feb 2016
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Cite this article
S. Meng, L.F. Reissig, C.-H. Tzou, K. Meng, W. Grisold, W. Weninger
Ultrasound of the Hypoglossal Nerve in the Neck: Visualization and Initial Clinical Experience with Patients
American Journal of Neuroradiology Feb 2016, 37 (2) 354-359; DOI: 10.3174/ajnr.A4494

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Ultrasound of the Hypoglossal Nerve in the Neck: Visualization and Initial Clinical Experience with Patients
S. Meng, L.F. Reissig, C.-H. Tzou, K. Meng, W. Grisold, W. Weninger
American Journal of Neuroradiology Feb 2016, 37 (2) 354-359; DOI: 10.3174/ajnr.A4494
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