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Research ArticleBrain

Stenotic Transverse Sinus Predisposes to Poststenting Hyperperfusion Syndrome as Evidenced by Quantitative Analysis of Peritherapeutic Cerebral Circulation Time

C.-J. Lin, F.-C. Chang, F.-Y. Tsai, W.-Y. Guo, S.-C. Hung, D.Y.-T. Chen, C.-H. Lin and C.-Y. Chang
American Journal of Neuroradiology June 2014, 35 (6) 1132-1136; DOI: https://doi.org/10.3174/ajnr.A3838
C.-J. Lin
aFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-Y.C.), Taipei Veterans General Hospital, Taipei, Taiwan
bSchool of Medicine (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-Y.C.), National Yang Ming University, Taipei, Taiwan
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F.-C. Chang
aFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-Y.C.), Taipei Veterans General Hospital, Taipei, Taiwan
bSchool of Medicine (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-Y.C.), National Yang Ming University, Taipei, Taiwan
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F.-Y. Tsai
cImaging Research Center (F.-Y.T., D.Y.-T.C.), Taipei Medical University, Taipei, Taiwan
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W.-Y. Guo
aFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-Y.C.), Taipei Veterans General Hospital, Taipei, Taiwan
bSchool of Medicine (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-Y.C.), National Yang Ming University, Taipei, Taiwan
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S.-C. Hung
aFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-Y.C.), Taipei Veterans General Hospital, Taipei, Taiwan
bSchool of Medicine (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-Y.C.), National Yang Ming University, Taipei, Taiwan
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D.Y.-T. Chen
cImaging Research Center (F.-Y.T., D.Y.-T.C.), Taipei Medical University, Taipei, Taiwan
dDepartment of Medical Imaging (D.Y.-T.C.), Shuang-Ho Hospital, New Taipei City, Taiwan
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C.-H. Lin
eGraduate Institute of Epidemiology and Preventive Medicine (C.-H.L.), National Taiwan University, Taipei, Taiwan.
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C.-Y. Chang
aFrom the Department of Radiology (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-Y.C.), Taipei Veterans General Hospital, Taipei, Taiwan
bSchool of Medicine (C.-J.L., F.-C.C., W.-Y.G., S.-C.H., C.-Y.C.), National Yang Ming University, Taipei, Taiwan
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    Fig 1.

    Anteroposterior view of quantitative brain DSA of a 51-year-old woman. The midpoint of the cervical portion of the internal carotid artery was selected for the arterial region of interest. The midpoint of the ipsilateral internal jugular vein was selected for venous region of interest. Cerebral circulation time was the time difference between the 2 ROIs.

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    Fig 2.

    Receiver operating characteristic analysis of prestent CCT (A) and ΔCCT (B).

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    Fig 3.

    A 51-year-old woman with 90% left internal carotid artery stenosis. Color-coded cerebral DSA demonstrated an ipsilateral atretic transverse sinus in Fig 1. A–C, Prestent MR imaging shows an old infarct in the occipital subcortical white matter. She had headache with nausea 8 hours after the procedure. D–F, MR imaging 12 hours after the procedure shows increased signal intensity over the left occipital subcortical white matter.

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    Table 1:

    Patient characteristics between those with an ipsilateral stenotic transverse sinus (group A) and those with a normal transverse sinus (group B)

    Group A (n = 15)Group B (n = 34)
    Age (yr)74.5 + 10.273.9 + 10.3
    Sex (M/F)12:331:5
    Hypertension5 (33%)13 (38%)
    MR imaging evidence of prior stroke6 (40%)16 (47%)
    Stenosis degree82%81%
    Lack of collaterals in MRA2 (13%)6 (18%)
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    Table 2:

    Peritherapeutic circulation times and MR imaging findings between those with an ipsilateral stenotic transverse sinus (group A) and those with a normal transverse sinus (group B)

    Group A (n = 15)Group B (n = 34)P Value
    DSA
        Prestent CCT6.9 ± 1.26.2 ± 1.1.14
        Poststent CCT6.2 ± 1.56.2 ± 1.5.98
        ΔCCT0.65 ± 1.3−0.12 ± 1.4.045a
    MR imaging
        High SI in periventricular white matter30<.001a
        Gyral effacement20<.001a
    • Note:—SI indicates signal intensity.

    • ↵a Statically significant.

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    Table 3:

    Characteristics of 3 patients with high SI in the white matter in FLAIR sequences

    PatientRecent InfarctHPSAge (yr)SexComplicationsStenotic DegreePre-CCT (sec)Post-CCT (sec)ΔCCT (sec)
    1NoHeadache51FNo85%7.55.841.66
    2NoNo79FNo77%5.55.030.47
    3NoNo81MNo78%10.09.01.0
    • Note:—SI indicates signal intensity.

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American Journal of Neuroradiology: 35 (6)
American Journal of Neuroradiology
Vol. 35, Issue 6
1 Jun 2014
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C.-J. Lin, F.-C. Chang, F.-Y. Tsai, W.-Y. Guo, S.-C. Hung, D.Y.-T. Chen, C.-H. Lin, C.-Y. Chang
Stenotic Transverse Sinus Predisposes to Poststenting Hyperperfusion Syndrome as Evidenced by Quantitative Analysis of Peritherapeutic Cerebral Circulation Time
American Journal of Neuroradiology Jun 2014, 35 (6) 1132-1136; DOI: 10.3174/ajnr.A3838

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Stenotic Transverse Sinus Predisposes to Poststenting Hyperperfusion Syndrome as Evidenced by Quantitative Analysis of Peritherapeutic Cerebral Circulation Time
C.-J. Lin, F.-C. Chang, F.-Y. Tsai, W.-Y. Guo, S.-C. Hung, D.Y.-T. Chen, C.-H. Lin, C.-Y. Chang
American Journal of Neuroradiology Jun 2014, 35 (6) 1132-1136; DOI: 10.3174/ajnr.A3838
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