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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatrics

CT and MRI of Pediatric Skull Lesions with Fluid-Fluid Levels

S.A. Nabavizadeh, L.T. Bilaniuk, T. Feygin, K.V. Shekdar, R.A. Zimmerman and A. Vossough
American Journal of Neuroradiology March 2014, 35 (3) 604-608; DOI: https://doi.org/10.3174/ajnr.A3712
S.A. Nabavizadeh
aFrom the Department of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
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L.T. Bilaniuk
aFrom the Department of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
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T. Feygin
aFrom the Department of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
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K.V. Shekdar
aFrom the Department of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
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R.A. Zimmerman
aFrom the Department of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
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A. Vossough
aFrom the Department of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
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    Fig 1.

    MR imaging in a patient with Langerhans cell histiocytosis. Axial T1- (A) and T2-weighted (B) images reveal multiple FFLs. An enhancing solid soft-tissue component is seen medially on postcontrast axial (C) and coronal (D) T1-weighted images.

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    Fig 2.

    CT and MR imaging findings in a patient with an aneurysmal bone cyst. Coronal CT scan (A) reveals marked bone expansion by a well-defined cystic-appearing mass projecting into the left temporal fossa with very thin remnants of the bony cortex seen in the wall (arrows). T2-weighted (B) and precontrast T1-weighted (C) images reveal multiple FFLs. Peripheral and septal enhancement is noted on CT (A) and postcontrast T1-weighted images (D), but no large enhancing solid soft-tissue component is identified.

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    Fig 3.

    CT and MR imaging findings in a patient with Langerhans cell histiocytosis. Noncontrast CT (A) reveals a lytic lesion with a prominent soft-tissue component and well-defined bone destruction. An FFL is faintly seen (arrow). T2-weighted image (B) and postcontrast T1-weighted image (C) show a few FFLs and enhancement of soft-tissue components, respectively. Axial T2-weighted image (D) following chemotherapy now reveals an increase in the number of FFLs.

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    Fig 4.

    MR imaging findings in a patient with neuroblastoma demonstrate typical bone marrow infiltration and expansion by metastases (A). Multiple small FFLs are seen in the lesions (B).

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    Fig 5.

    MR imaging of a 3-month-old patient found to have a bump on the head on physical examination. T2-weighted axial image shows an FFL within a cephalohematoma (arrow), confirmed to be within the bone on multiple planes and sequences (not shown).

Tables

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  • Demographic, clinical, imaging, and histopathologic findings of pediatric patients with FFLs in skull lesions

    PatientSexAge (yr)LocationCTNo. of FFLs on CTMRINo. of FFLs on MRIHistory of TraumaHistopathologyFinal Diagnosis
    1M4Right parietalNCCT9CE MRI17Minor head traumaLCHLCH
    2F0.75Occipital–N/ACE MRI2−LCHLCH
    3F13Left temporalCECT3CE MRI19−ABCABC
    4F10Left parietalNCCT0CE MRI1Forceps deliveryNoneCephalohematoma
    5M0.25Left parietal–N/ACE MRI4−NoneCephalohematoma
    6M1.5Sphenoid–N/ACE MRI2−NoneNeuroblastoma
    7F12Left frontalNCCT3CE MRI5Minor head traumaLCHLCH
    8M11Left temporalCECT2CE MRI6−ABC in the setting of fibrous dysplasiaABC
    9M0.5Left orbitCECT1CE MRI14−LCHLCH
    10M0.02Right parietal–N/ACE MRI3+NoneCephalohematoma
    11F16Right occipital and temporalNCCT7CE MRI29−ABCABC
    • Note:—CECT indicates contrast-enhanced CT; CE, contrast-enhanced; −, none; +, positive for trauma; N/A, not applicable.

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American Journal of Neuroradiology: 35 (3)
American Journal of Neuroradiology
Vol. 35, Issue 3
1 Mar 2014
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Cite this article
S.A. Nabavizadeh, L.T. Bilaniuk, T. Feygin, K.V. Shekdar, R.A. Zimmerman, A. Vossough
CT and MRI of Pediatric Skull Lesions with Fluid-Fluid Levels
American Journal of Neuroradiology Mar 2014, 35 (3) 604-608; DOI: 10.3174/ajnr.A3712

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CT and MRI of Pediatric Skull Lesions with Fluid-Fluid Levels
S.A. Nabavizadeh, L.T. Bilaniuk, T. Feygin, K.V. Shekdar, R.A. Zimmerman, A. Vossough
American Journal of Neuroradiology Mar 2014, 35 (3) 604-608; DOI: 10.3174/ajnr.A3712
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