Article Figures & Data
Figures
- Fig 1.
Meta-analysis of death and rate of poor functional outcome at 1 year.
- Fig 2.
Meta-analysis of rebleeding from the treated aneurysm during the first month after treatment.
Tables
- Table 1:
Summary of published randomized clinical trials of surgery versus coiling for ruptured aneurysms
Kuopio ISAT BRAT Period February 1995 to August 1997 1997 to September 2002 March 2003 to January 2007 Single-center/multicenter Single Multicenter Single Enrollment <72 hours <28 days <14 days Total patients screened 242 9559 725 Patients enrolled 109 2143 471 Mean age (years) Endovascular 49 52 54 Surgery 50 52 53 No. of patients allocated endovascular 52 1073 233 No. of patients allocated surgery 57 1070 238 Good grade, n (% of total) 93 (85.3) 2018 (94.2) 380 (80.7) Poor grade, n (% of total) 16 (13.7) 94 (5.8) 91 (19.3) Crossovers From endovascular to surgery 12 9 75 From surgery to endovascular 4 38 4 Kuopio ISAT BRAT Outcome assessment 1 year Single neurosurgeon Postal questionnaire filled out by patients Research nurse Definition poor outcome GOS mRS 3–6 mRS 3–6 Poor outcome Endovascular 12/52 (23%) 250/1063 (23.5%) 46/198 (23%) Surgery 19/57 (33%) 326/1055 (30.9%) 69/205 (34%) Death Endovascular 7/52 (13%) 85/1063 (8.0%) NA Surgery 9/57 (16%) 105/1055 (9.9%) NA Rebleeding Endovascular Day 1–30 1 20 1a Day 31–365 0 6 0 >1 year 0 10 0 Surgery Day 1–30 0 6 1 Day 31–365 0 4 0 >1 year 0 3a 0 One-year follow-up complete Endovascular 100%b 1063/1073 (99%) 198/233 (85%) Surgery 1055/1070 (98.6%) 205/238 (86%)
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