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Research ArticleBrain

Regional Leptomeningeal Score on CT Angiography Predicts Clinical and Imaging Outcomes in Patients with Acute Anterior Circulation Occlusions

B.K. Menon, E.E. Smith, J. Modi, S.K. Patel, R. Bhatia, T.W.J. Watson, M.D. Hill, A.M. Demchuk and M. Goyal
American Journal of Neuroradiology October 2011, 32 (9) 1640-1645; DOI: https://doi.org/10.3174/ajnr.A2564
B.K. Menon
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E.E. Smith
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J. Modi
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S.K. Patel
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R. Bhatia
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T.W.J. Watson
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M.D. Hill
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A.M. Demchuk
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M. Goyal
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    Fig 1.

    A, rLMC score is based on scoring pial and lenticulostriate arteries (0, no; 1, less; 2, equal or more prominent compared with matching region in opposite hemisphere) in 6 ASPECTS regions (M1–6) plus anterior cerebral artery region and basal ganglia. Pial arteries in the Sylvian sulcus are scored 0, 2, or 4. B, Left M1 MCA occlusion with prominent retrograde opacification of the pial arteries to the distal end of thrombus. rLMC score is 19. C, Right carotid “T occlusion” with patent ipsilateral A2 ACA segment and poor visualization of pial arteries in the right frontal and parietal regions. Note backfilling of pial arteries in the Sylvian sulcus with prominent well-visualized arteries in the temporal regions. Assessment of collateral status based on comparison of arteries in Sylvian sulcus alone suggests good PCA to MCA collaterals in the temporal regions and does not account for the poor PCA to ACA and ACA to MCA collaterals in the frontoparietal regions. rLMC score is 8. D, Left M1 MCA occlusion with poor leptomeningeal collateral status. All regions have less prominent or absent arteries. rLMC score is 7.

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    Fig 2.

    A, CTA showing occlusion of distal right M1 MCA. Poor contrast opacification of pial arteries even on the normal side (left) makes estimation of leptomeningeal collateral status difficult. B, Greater contrast opacification of the ipsilateral basal vein of Rosenthal than the MCA in a patient with occlusion of the distal left M1 MCA. Delayed triggering as evidenced by excessive venous contamination can result in overestimating collateral status.

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    Fig 3.

    Relationship between IA therapy and good outcome according to collateral score category (n = 133; 5 were excluded for baseline mRS >2). Cochran-Mantel-Haenszel test for homogeneity of ORs, P = .16.

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American Journal of Neuroradiology: 32 (9)
American Journal of Neuroradiology
Vol. 32, Issue 9
1 Oct 2011
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B.K. Menon, E.E. Smith, J. Modi, S.K. Patel, R. Bhatia, T.W.J. Watson, M.D. Hill, A.M. Demchuk, M. Goyal
Regional Leptomeningeal Score on CT Angiography Predicts Clinical and Imaging Outcomes in Patients with Acute Anterior Circulation Occlusions
American Journal of Neuroradiology Oct 2011, 32 (9) 1640-1645; DOI: 10.3174/ajnr.A2564

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Regional Leptomeningeal Score on CT Angiography Predicts Clinical and Imaging Outcomes in Patients with Acute Anterior Circulation Occlusions
B.K. Menon, E.E. Smith, J. Modi, S.K. Patel, R. Bhatia, T.W.J. Watson, M.D. Hill, A.M. Demchuk, M. Goyal
American Journal of Neuroradiology Oct 2011, 32 (9) 1640-1645; DOI: 10.3174/ajnr.A2564
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