Article Figures & Data
Figures
- Fig 1.
A, MIP of 3 mm thickness of the 1.5T scan. Two microbleeds are visible (arrows).B, MIP of 3 mm thickness of the TE1 at 7T and of the TE2 image (C). The 2 microbleeds are also visible on both the TE1 and TE2 images (arrows). Note the developmental venous anomaly visible on the 1.5T scan (arrowhead) and very clearly demarcated on the TE2 of the 7T scan. D-F, Magnifications of the microbleeds on the 1.5T scan, the TE1 of the 7T scan, and the TE2 of the 7T scan, respectively.
- Fig 2.
A, On this 1.5T scan, a hypointense lesion (arrow) is visible that is not a typical well-defined, round-shaped lesion as in the definition of a microbleed. This lesion was not scored as a microbleed on the 1.5T scan. In B and C, this same lesion is visible on the 7T scan. On the TE1 image (B), it is visible as a faint, round hypointensity and on the TE2 image (C), it is a clearly visible round hypointensity (arrow). On the 7T scan, both raters scored this lesion as a microbleed.
- Fig 3.
A, 1.5T scan shows a hypointense lesion (arrow) that can hardly be distinguished from noise and was not scored as a microbleed. On both the TE1 image (B) and TE2 image (C) of the 7T scan, this hypointense lesion is visible as a typical microbleed, showing enlargement at the TE2 due to the blooming effect. This lesion was scored as a microbleed by both observers.
- Fig 4.
A, 1.5T scan shows a well-defined, round, hypointense lesion (arrow) that was scored as a microbleed. However, on the TE1 of the 7T scan (B), this lesion is only visible as a very faint hypointensity and on the TE2 image (C) it appears as a small microbleed. On the 7T scan, this lesion was not scored as a microbleed.
Tables
Sequence Parameter 1.5T 7T TR (ms) 25 20.0 TE (ms) 35 2.5/15.0 Flip angle (°) 10 16–24 (variation over slab) Bandwidth (Hz/pixel) 100 203 Matrix size 276 × 226 508 × 399 Parallel imaging Yes (acceleration factor = 1.8) Yes (acceleration factor = 2.5) Flow compensation No Yes Section thickness (mm) 0.8 0.6 Gap (mm) None None No. of sections 125 167 Acquired voxel size (mm) 0.8 × 0.8 × 0.8 0.35 × 0.4 × 0.6 Interpolated voxel size (mm) 0.43 × 0.43 × 0.4 0.35 × 0.35 × 0.3 Acquisition time 6 min 56 s 8 min 50 s All Patients (n = 34) Age (yr)a 58 ± 12 Male gender (%) 85 Inclusion in SMART study with Vascular risk factors (%) 50 Cerebrovascular disease (%) 26 Peripheral artery disease (%) 15 Cardiovascular disease (%) 9 a Age is expressed as mean ± SD.
1.5T Observer 2 Total Microbleeds Absent Microbleeds Present Observer 1 Microbleeds absent 21 6 27 Microbleeds present 3 4 7 Total 24 10 34 7T Observer 2 Total Microbleeds Absent Microbleeds Present Observer 1 Microbleeds absent 18 7 25 Microbleeds present 2 7 9 Total 20 14 34 - Table 5:
Number of patients with visible microbleeds at 1.5T and 7T after consensus between the 2 observers
Consensus 2 observers 7T Total Microbleeds Absent Microbleeds Present 1.5T Microbleeds absent 17 9 26 Microbleeds present 0 8 8 Total 17 17 34
In this issue
Jump to section
Related Articles
Cited By...
- Microinfarcts in the Deep Gray Matter on 7T MRI: Risk Factors, MRI Correlates, and Relation to Cognitive Functioning--The SMART-MR Study
- Cerebral microbleeds: from depiction to interpretation
- Detection of Cerebral Microbleeds With Venous Connection at 7-Tesla MRI
- 7T MRI for neurodegenerative dementias in vivo: a systematic review of the literature
- Cerebral Microbleeds, Vascular Risk Factors, and Magnetic Resonance Imaging Markers: The Northern Manhattan Study
- Ventricular Microaneurysms in Moyamoya Angiopathy Visualized with 7T MR Angiography
- Ultra-High-Field MR Imaging in Polymicrogyria and Epilepsy
- Cerebral Microvascular Lesions on High-Resolution 7-Tesla MRI in Patients With Type 2 Diabetes
- Visual Cerebral Microbleed Detection on 7T MR Imaging: Reliability and Effects of Image Processing
- Strictly Lobar Microbleeds Are Associated With Executive Impairment in Patients With Ischemic Stroke or Transient Ischemic Attack
- Improved MR Imaging Detection of Cerebral Microbleeds More Accurately Identifies Persons with Vasculopathy