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Case ReportBrain

Marchiafava-Bignami Disease with Widespread Lesions and Complete Recovery

C.-S. Tung, S.-L. Wu, J.-C. Tsou, S.-P. Hsu, H.-C. Kuo and H.-W. Tsui
American Journal of Neuroradiology September 2010, 31 (8) 1506-1507; DOI: https://doi.org/10.3174/ajnr.A1897
C.-S. Tung
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S.-L. Wu
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J.-C. Tsou
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S.-P. Hsu
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H.-C. Kuo
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H.-W. Tsui
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    Fig 1.

    MR images obtained on day 5. A–D, On axial T2WI, the lesions appear hyperintense in the middle cerebellar peduncles, cerebral peduncles, internal capsules, and hemispheric white matter. E–H, On corresponding DWI, the lesions appear hyperintense. I, On sagittal T2WI, hyperintense lesions are seen throughout the corpus callosum.

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    Fig 2.

    Follow-up MR images obtained on days 17 (A–C) and 30 (D–F). A, On axial T2WI, hyperintense lesions are seen in the splenium and internal capsules. B and C, On axial DWI and an ADC map, the lesions appear hyperintense in DWI and hypointense on the ADC map in the splenium and internal capsule. D–F, On follow-up MR images obtained 3 months after onset, note the disappearance of all signal-intensity abnormalities on axial T2WI, DWI, and sagittal T2WI.

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American Journal of Neuroradiology: 31 (8)
American Journal of Neuroradiology
Vol. 31, Issue 8
1 Sep 2010
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C.-S. Tung, S.-L. Wu, J.-C. Tsou, S.-P. Hsu, H.-C. Kuo, H.-W. Tsui
Marchiafava-Bignami Disease with Widespread Lesions and Complete Recovery
American Journal of Neuroradiology Sep 2010, 31 (8) 1506-1507; DOI: 10.3174/ajnr.A1897

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Marchiafava-Bignami Disease with Widespread Lesions and Complete Recovery
C.-S. Tung, S.-L. Wu, J.-C. Tsou, S.-P. Hsu, H.-C. Kuo, H.-W. Tsui
American Journal of Neuroradiology Sep 2010, 31 (8) 1506-1507; DOI: 10.3174/ajnr.A1897
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  • “CHOICES”: An acronym to aid in delineating potential causes of non-metabolic, non-infectious acute toxic leukoencephalopathy
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  • Clinical and neuroradiological features of 15 patients diagnosed with Marchiafava-Bignami disease
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    Chinese Medical Journal 2019 132 15
  • “Ears of the Lynx” Sign in a Marchiafava–Bignami patient: Structural Basis and Fiber‐Tracking DTI Contribution to the Understanding of this Imaging Abnormality
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    Journal of Neuroimaging 2014 24 2

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