PT  - JOURNAL ARTICLE
AU  - Tung, C.-S.
AU  - Wu, S.-L.
AU  - Tsou, J.-C.
AU  - Hsu, S.-P.
AU  - Kuo, H.-C.
AU  - Tsui, H.-W.
TI  - Marchiafava-Bignami Disease with Widespread Lesions and Complete Recovery
AID  - 10.3174/ajnr.A1897
DP  - 2010 Sep 01
TA  - American Journal of Neuroradiology
PG  - 1506--1507
VI  - 31
IP  - 8
4099  - http://www.ajnr.org/content/31/8/1506.short
4100  - http://www.ajnr.org/content/31/8/1506.full
SO  - Am. J. Neuroradiol.2010 Sep 01; 31
AB  - SUMMARY: MBD is a rare disorder strongly associated with alcoholism. It is characterized pathologically by demyelination and necrosis of the corpus callosum. MBD presents with severe neurologic deficits and significant sequelae developing in most survivors. We report a patient with total clinical recovery. Serial MR imaging demonstrated typical lesions with restricted diffusion in the acute stage and total resolution without atrophy or cystic change. ADCapparent diffusion coefficientDWIdiffusion-weighted imagingMBDMarchiafava-Bignami diseaseT1WIT1-weighted imagingT2WIT2-weighted imaging