Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleBrain
Open Access

Positional Relationship between Recurrent Intracerebral Hemorrhage/Lacunar Infarction and Previously Detected Microbleeds

Y. Sueda, H. Naka, T. Ohtsuki, T. Kono, S. Aoki, T. Ohshita, E. Nomura, S. Wakabayashi, T. Kohriyama and M. Matsumoto
American Journal of Neuroradiology September 2010, 31 (8) 1498-1503; DOI: https://doi.org/10.3174/ajnr.A2100
Y. Sueda
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H. Naka
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T. Ohtsuki
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T. Kono
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Aoki
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T. Ohshita
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
E. Nomura
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Wakabayashi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T. Kohriyama
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Matsumoto
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Fig 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 1.

    Representative cases. T2*-weighted MR image (A) and CT scan (B) in an 84-year-old patient. Recurrent right cerebellar hemorrhage (arrow) corresponds to the location of MBs detected 9 months before (arrowhead). T2*-weighted MR image (C) and CT scan (D) in an 80-year-old patient. Recurrent left thalamic hemorrhage (arrow) corresponds to the location of MBs detected 35 months before (arrowhead). T2*-weighted MR image (E) and CT scan (F) in an 85-year-old patient. Recurrent left lobar hemorrhage (arrow) corresponds to the location of MBs detected 3 months before (arrowhead).

  • Fig 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 2.

    Correspondence of MBs in each part of the hematoma. The correspondence ratio was higher in the deep ICH group, particularly in thalamic and putaminal hemorrhage, than in the lobar ICH group.

Tables

  • Figures
    • View popup
    Table 1:

    Characteristics of patients with ICH and LI

    CharacteristicICH (n = 34)LI (n = 21)P Valuea
    Demographic data
        Median age, (yr) (range)69.5 (51–84)72 (57–89).020
        Male sex, No. (%)25 (73.5)13 (61.9).365
    Vascular risk factors
        Hypertension (%)97.01001.000
        Diabetes mellitus (%)24.231.6.746
        Hyperlipidemia (%)45.252.6.608
    Antithrombotic therapy (%)56.378.9.135
    Prior stroke subtype, No. (%)
        ICH13 (38.2)2 (9.5).029
        LI12 (35.3)18 (85.7).005
        ATBI4 (11.8)1 (5.9).639
        CE5 (14.7)0 (0).144
    No. of MBs, median (range)12.5 (1–73)6 (1–83).070
    Time from prior stroke, median day (range)247.5 (14–1873)179 (3–860).188
    Correspondence to MBs, No. (%)21 (61.8)1 (4.8)<.001
    • a χ2 test, Fisher exact test, Student t test, or Mann-Whitney U test were used.

    • View popup
    Table 2:

    Characteristics of corresponding and noncorresponding groups in patients with ICH

    CharacteristicCorresponding (n = 21)Noncorresponding (n = 13)P Valuea
    Demographic data
        Median age, (yr) (range)70 (51–84)62 (55–78).188
        Male sex, No. (%)17 (81.0)8 (61.5).151
    Vascular risk factors
        Hypertension (%)10092.3.934
        Diabetes mellitus (%)25.030.8.681
        Hypercholesterolemia (%)26.361.5.071
    Antithrombotic therapy (%)42.176.9.075
    Prior stroke subtype, No. (%)
        ICH8 (38.1)5 (35.7).886
        LI9 (42.9)3 (21.4).282
        ATBI1 (4.8)3 (21.4).279
        CE3 (14.3)2 (14.3)1.000
    Hemorrhage volume, median (range) (cm3)15.1 (0.36–162)3.43 (0.16–58.4).077
    No. of MBs, median (range)16 (4–73)4 (1–49).014
    Time from prior stroke, median day (range)263 (58–1873)150 (14–1407).748
    • a χ2 test, Fisher exact test, Student t test, or Mann-Whitney U test were used.

    • View popup
    Table 3:

    Characteristics of deep ICH and lobar ICH groups

    CharacteristicDeep ICH (n = 24)Lobar ICH (n = 10)P Valuea
    Demographic data
        Median age (yr) (range)69.5 (51–84)66 (55–84).694
        Male sex, No. (%)17 (70.8)8 (80.0).692
    Vascular risk factors
        Hypertension (%)10090.0.303
        Diabetes mellitus (%)26.120.01.000
        Hyperlipidemia (%)45.544.41.000
    Antithrombotic therapy (%)50.077.8.237
    Prior stroke subtype, No. (%)
        ICH9 (37.5)4 (40.0)1.000
        LI11 (45.8)1 (10.0).061
        ATBI1 (4.2)3 (30.0).067
        CE3 (12.5)2 (20.0).618
    Hemorrhage volume, median (range) (cm3)6.92 (0.16–66.9)30.3 (0.69–162).287
    No. of MBs, median (range)13 (1–56)8 (1–73).304
    Time from prior stroke, median day (range)292.5 (14–1873)187.5 (79–1033).696
    Correspondence to MBs, No. (%)19 (79.2)2 (20.0).002
    • a χ2 test, Fisher exact test, Student t test, or Mann-Whitney U test were used.

    • View popup
    Table 4:

    Characteristics of the corresponding and noncorresponding groups in the deep ICH group

    CharacteristicCorresponding (n = 19)Noncorresponding (n = 5)P Valuea
    Demographic data
        Median age, (yr) (range)70 (51–84)67 (60–78).996
        Male sex, No. (%)15 (78.9)2 (40.0).126
    Vascular risk factors
        Hypertension (%)100100-
        Diabetes mellitus (%)16.760.0.078
        Hypercholesterolemia (%)29.460.0.309
    Antithrombotic therapy (%)35.3100.035
    Prior stroke subtype, No. (%)
        ICH7 (36.8)2 (40.0)1.000
        LI9 (47.4)2 (40.0)1.000
        ATBI0 (0)1 (20.0).208
        CE3 (15.8)0 (0)1.000
    No. of MBs, median (range)
        In the whole brain16 (4–56)4 (1–11)<.001
        In the deep gray matter8 (3–28)2 (1–8).015
    Time from prior stroke, median day (range)322 (58–1873)99 (14–1407).746
    • a χ2 test, Fisher exact test, Student t test, or Mann-Whitney U test were used.

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 31 (8)
American Journal of Neuroradiology
Vol. 31, Issue 8
1 Sep 2010
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Positional Relationship between Recurrent Intracerebral Hemorrhage/Lacunar Infarction and Previously Detected Microbleeds
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Y. Sueda, H. Naka, T. Ohtsuki, T. Kono, S. Aoki, T. Ohshita, E. Nomura, S. Wakabayashi, T. Kohriyama, M. Matsumoto
Positional Relationship between Recurrent Intracerebral Hemorrhage/Lacunar Infarction and Previously Detected Microbleeds
American Journal of Neuroradiology Sep 2010, 31 (8) 1498-1503; DOI: 10.3174/ajnr.A2100

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Positional Relationship between Recurrent Intracerebral Hemorrhage/Lacunar Infarction and Previously Detected Microbleeds
Y. Sueda, H. Naka, T. Ohtsuki, T. Kono, S. Aoki, T. Ohshita, E. Nomura, S. Wakabayashi, T. Kohriyama, M. Matsumoto
American Journal of Neuroradiology Sep 2010, 31 (8) 1498-1503; DOI: 10.3174/ajnr.A2100
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Abbreviations
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Statin Use and Microbleeds in Patients With Spontaneous Intracerebral Hemorrhage
  • Crossref (17)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Statin Use and Microbleeds in Patients With Spontaneous Intracerebral Hemorrhage
    Diogo C. Haussen, Nils Henninger, Sandeep Kumar, Magdy Selim
    Stroke 2012 43 10
  • Intracerebral Hemorrhage in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
    Yi-Chu Liao, Yu-Chen Hu, Chih-Ping Chung, Yen-Feng Wang, Yuh-Cherng Guo, Yu-Shuen Tsai, Yi-Chung Lee
    Stroke 2021 52 3
  • The Practical Management of Intracerebral Hemorrhage Associated with Oral Anticoagulant Therapy
    Luca Masotti, Mario Di Napoli, Daniel A. Godoy, Daniela Rafanelli, Giancarlo Liumbruno, Nicholas Koumpouros, Giancarlo Landini, Alessandro Pampana, Roberto Cappelli, Daniela Poli, Domenico Prisco
    International Journal of Stroke 2011 6 3
  • Asymptomatic Cerebral Microbleeds in Adult Patients with Moyamoya Disease: A Prospective Cohort Study with 2 Years of Follow-Up
    Wen Sun, Cuiping Yuan, Wenhua Liu, Yongkun Li, Zhixin Huang, Wusheng Zhu, Min Li, Gelin Xu, Xinfeng Liu
    Cerebrovascular Diseases 2013 35 5
  • Imaging Ischemic and Hemorrhagic Disease of the Brain in Dogs
    Susan A. Arnold, Simon R. Platt, Karine P. Gendron, Franklin D. West
    Frontiers in Veterinary Science 2020 7
  • Antiplatelet Therapy as a Risk Factor for Microbleeds in Intracerebral Hemorrhage Patients: Analysis Using Specific Antiplatelet Agents
    Hiromitsu Naka, Eiichi Nomura, Jyuri Kitamura, Eiji Imamura, Shinichi Wakabayashi, Masayasu Matsumoto
    Journal of Stroke and Cerebrovascular Diseases 2013 22 6
  • MRI CHARACTERISTICS OF CEREBRAL MICROBLEEDS IN FOUR DOGS
    Caroline V. Fulkerson, Benjamin D. Young, Nicolette D. Jackson, Brian Porter, Jonathan M. Levine
    Veterinary Radiology & Ultrasound 2012 53 4
  • Associations and implications of cerebral microbleeds
    Timothy J. Kleinig
    Journal of Clinical Neuroscience 2013 20 7
  • Contribution of Deep Microbleeds to Stroke Recurrence: Differences between Patients with Past Deep Intracerebral Hemorrhages and Lacunar Infarctions
    Toshio Imaizumi, Shigeru Inamura, Tatsufumi Nomura
    Journal of Stroke and Cerebrovascular Diseases 2015 24 8
  • Prevalence and Impact of Cerebral Microbleeds on Clinical and Safety Outcomes in Acute Ischaemic Stroke Patients Receiving Reperfusion Therapy: A Systematic Review and Meta-Analysis
    Shraddha Tipirneni, Peter Stanwell, Robert Weissert, Sonu M. M. Bhaskar
    Biomedicines 2023 11 10

More in this TOC Section

  • Multimodal CT Provides Improved Performance for Lacunar Infarct Detection
  • Optimal MRI Sequence for Identifying Occlusion Location in Acute Stroke: Which Value of Time-Resolved Contrast-Enhanced MRA?
  • Evaluating the Effects of White Matter Multiple Sclerosis Lesions on the Volume Estimation of 6 Brain Tissue Segmentation Methods
Show more BRAIN

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire