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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleNeurointerventionF

A Prospective Trial of 3T and 1.5T Time-of-Flight and Contrast-Enhanced MR Angiography in the Follow-Up of Coiled Intracranial Aneurysms

T.J. Kaufmann, J. Huston, H.J. Cloft, J. Mandrekar, L. Gray, M.A. Bernstein, J.L. Atkinson and D.F. Kallmes
American Journal of Neuroradiology May 2010, 31 (5) 912-918; DOI: https://doi.org/10.3174/ajnr.A1932
T.J. Kaufmann
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J. Huston III
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H.J. Cloft
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J. Mandrekar
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L. Gray
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M.A. Bernstein
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J.L. Atkinson
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D.F. Kallmes
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Article Figures & Data

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    Fig 1.

    MRA technique sensitivity for any aneurysm remnant, larger (class 3 or 4) remnants, and the detection of growth since previous DSA; 95% confidence intervals are shown.

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    Fig 2.

    MRA technique specificity for any aneurysm remnant, larger (class 3 or 4) remnants, and the detection of growth since previous DSA; 95% confidence intervals are shown.

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    Fig 3.

    DSA (A), 3T TOF-MRA MIP (B), 3T CE-MRA MIP (C), 3T TOF-MRA source image (D), and 3T CE-MRA source image (E). A class 4 coiled anterior communicating artery remnant/recurrence (white arrows in A, B, and C) is better depicted as a large remnant with CE-MRA (C) than with TOF-MRA (B). Digitally subtracted coils are seen in A (black arrows). However, by using our clinical scanning protocols, localization of the coil mass is improved with TOF-MRA (D, white arrow) relative to CE-MRA (E). This may be related to better visualization of the surrounding brain tissue with TOF than with CE-MRA because of a shorter TR and higher flip angle of the CE-MRA and a longer TE with TOF-MRA.

Tables

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    Table 1:

    MRA scanning parameters

    1.5T TOF1.5T CE3T TOF3T CE
    TE6.9Minimum3.4Minimum
    TR366.6388.6
    Flip angle25°45°25°40°
    SequenceTOF SPGRFast TOF SPGRTOF SPGRFast TOF SPGR
    Matrix/NEX256/224/1256/224/1512/256/1416/224/1
    Nominal section thickness (mm)1.4 (3 slabs)1.21.4 (3 slabs)1.2
    Zero-fill interpolationYesYesYesYes
    LOC/overlap32/64832/648
    FOV (cm)18221822
    Receiver bandwidth (± kHz)16321632
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    Table 2:

    Pair-wise comparisons of sensitivity and specificity of MRA techniques

    MRA TechniqueP Value Comparing SensitivitiesP Value Comparing Specificities
    Aneurysm class: 1 vs 2 ,3, 4 (for any remnant)
        1.5 TOF vs 1.5 CE.3173.1797
        1.5 TOF vs 3 TOF.31731
        1.5 TOF vs 3 CE1.2568
        1.5 CE vs 3 TOF.3173.1797
        1.5 CE vs 3 CE.41421
        3 TOF vs 3 CE11
    Aneurysm class: 1, 2 vs 3, 4 (for larger remnants)
        1.5 TOF vs 1.5 CE.04551
        1.5 TOF vs 3 TOF11
        1.5 TOF vs 3 CE.0455.5637
        1.5 CE vs 3 TOF.10251
        1.5 CE vs 3 CE1.5637
        3 TOF vs 3 CE11
    Aneurysm occlusion: better or same vs worse
        1.5 TOF vs 1.5 CE1.6547
        1.5 TOF vs 3 TOF.3173.3173
        1.5 TOF vs 3 CE.1573.5637
        1.5 CE vs 3 TOF.3173.5637
        1.5 CE vs 3 CE.15731
        3 TOF vs 3 CE.3173.5637
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American Journal of Neuroradiology: 31 (5)
American Journal of Neuroradiology
Vol. 31, Issue 5
1 May 2010
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T.J. Kaufmann, J. Huston, H.J. Cloft, J. Mandrekar, L. Gray, M.A. Bernstein, J.L. Atkinson, D.F. Kallmes
A Prospective Trial of 3T and 1.5T Time-of-Flight and Contrast-Enhanced MR Angiography in the Follow-Up of Coiled Intracranial Aneurysms
American Journal of Neuroradiology May 2010, 31 (5) 912-918; DOI: 10.3174/ajnr.A1932

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A Prospective Trial of 3T and 1.5T Time-of-Flight and Contrast-Enhanced MR Angiography in the Follow-Up of Coiled Intracranial Aneurysms
T.J. Kaufmann, J. Huston, H.J. Cloft, J. Mandrekar, L. Gray, M.A. Bernstein, J.L. Atkinson, D.F. Kallmes
American Journal of Neuroradiology May 2010, 31 (5) 912-918; DOI: 10.3174/ajnr.A1932
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  • Imaging Follow-Up of Intracranial Aneurysms Treated by Endovascular Means: Why, When, and How?
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  • Review of 2 Decades of Aneurysm-Recurrence Literature, Part 2: Managing Recurrence after Endovascular Coiling
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  • Temporal Evolution of Susceptibility Artifacts from Coiled Aneurysms on MR Angiography: An In Vivo Canine Study
  • Use of CT Angiography in Comparison with Other Imaging Techniques for the Determination of Embolus and Remnant Size in Experimental Aneurysms Embolized with Hydrogel Filaments
  • Observer Agreement Regarding the Necessity of Retreatment of Previously Coiled Recurrent Cerebral Aneurysms
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