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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleBrainT
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Multiple Inflow Pulsed Arterial Spin-Labeling Reveals Delays in the Arterial Arrival Time in Minor Stroke and Transient Ischemic Attack

B.J. MacIntosh, A.C. Lindsay, I. Kylintireas, W. Kuker, M. Günther, M.D. Robson, J. Kennedy, R.P. Choudhury and P. Jezzard
American Journal of Neuroradiology November 2010, 31 (10) 1892-1894; DOI: https://doi.org/10.3174/ajnr.A2008
B.J. MacIntosh
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A.C. Lindsay
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I. Kylintireas
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W. Kuker
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M. Günther
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M.D. Robson
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J. Kennedy
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R.P. Choudhury
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P. Jezzard
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    Fig 1.

    Acute images for 3 patients with decreasing infarct volumes. Patient 1 shows a delayed AAT region (hyperintensity) in the affected hemisphere, where CBF is reduced (hypointensity). Patient 12 shows reduced CBF in the affected hemisphere and delayed AAT, while maps for Patient 9 have normal findings. Abnormal CBF and AAT regions are outlined in red.

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    Fig 2.

    AAT hemispheric asymmetry index is displayed as a bar plot for each patient. Control cohort data are more symmetric about zero with less variance. Patient data are significantly different from those of controls (P < .048). Light gray indicates DWI-positive; dark gray, DWI-negative; diamond datum, control participant.

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    Table 1:

    Patient demographics with diagnoses

    Patient No.SexAge (yr)Carotid Stenosis (%)DWI (mL)NIHSS ScoreBarthel IndexbTime to Scan (hr)aClinical DiagnosisReport (Outcome)
    LeftRight
    1F4896049.101100104StrokeLeft frontal embolic
    2M661506.1036017StrokeLeft embolic MCA
    3M8501006.25350103StrokeRight embolic
    4M8170303.2119072StrokeRight embolic
    5M9250301.5609074StrokeLeft subcortical
    6M703000.890100194TIALeft, unknown etiology
    7M7150100.00010045TIADWI negative, no lesion
    8M8160400.7605560StrokeLeft cortical
    9F7065350.73010044TIARight frontal embolic
    10M69651005.9719596StrokeLeft frontal embolic
    11F6810700.000100112TIADWI negative, no lesion
    12M7960900.46010044StrokeRight embolic MCA
    13M8270300.48010068StrokeLeft embolic MCA
    14M6240700.861100143StrokeLeft thalamic
    15M8445504.21655131StrokeRight frontal embolic
    • a Time to scan is the time in hours from symptom onset to MR imaging.

    • b Barthel Index of Activities of Daily Living

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    Table 2:

    Patient statisticsa

    StatisticsAge (yr)DWI (mL)NIHSS ScoreBarthel IndexbTime to Scan (hr)
    Mean745.418687
    Minimum48005017
    Maximum92496100194
    Median710.9010074
    SD1112.322046
    • a Time to scan is the time in hours from symptom onset to MR imaging.

    • b Barthel Index of Activities of Daily Living

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American Journal of Neuroradiology: 31 (10)
American Journal of Neuroradiology
Vol. 31, Issue 10
1 Nov 2010
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Cite this article
B.J. MacIntosh, A.C. Lindsay, I. Kylintireas, W. Kuker, M. Günther, M.D. Robson, J. Kennedy, R.P. Choudhury, P. Jezzard
Multiple Inflow Pulsed Arterial Spin-Labeling Reveals Delays in the Arterial Arrival Time in Minor Stroke and Transient Ischemic Attack
American Journal of Neuroradiology Nov 2010, 31 (10) 1892-1894; DOI: 10.3174/ajnr.A2008

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Multiple Inflow Pulsed Arterial Spin-Labeling Reveals Delays in the Arterial Arrival Time in Minor Stroke and Transient Ischemic Attack
B.J. MacIntosh, A.C. Lindsay, I. Kylintireas, W. Kuker, M. Günther, M.D. Robson, J. Kennedy, R.P. Choudhury, P. Jezzard
American Journal of Neuroradiology Nov 2010, 31 (10) 1892-1894; DOI: 10.3174/ajnr.A2008
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