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Research ArticleBRAIN

Simple Assessment of Cerebral Hemodynamics Using Single-Slab 3D Time-of-Flight MR Angiography in Patients with Cervical Internal Carotid Artery Steno-Occlusive Diseases: Comparison with Quantitative Perfusion Single-Photon Emission CT

R. Hirooka, K. Ogasawara, T. Inoue, S. Fujiwara, M. Sasaki, K. Chida, D. Ishigaki, M. Kobayashi, H. Nishimoto, Y. Otawara, E. Tsushima and A. Ogawa
American Journal of Neuroradiology March 2009, 30 (3) 559-563; DOI: https://doi.org/10.3174/ajnr.A1389
R. Hirooka
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K. Ogasawara
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T. Inoue
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S. Fujiwara
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M. Sasaki
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K. Chida
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D. Ishigaki
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M. Kobayashi
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H. Nishimoto
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Y. Otawara
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E. Tsushima
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A. Ogawa
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    Fig 1.

    Degree of visualization of the ipsilateral MCA on brain MRA was graded as follows: all M3 branches of the left MCA could be visualized to the cortical surface (grade A), one M3 branch could not be visualized to the cortical surface (grade B, arrow), one M2 branch could not be visualized along its course (grade C, arrow), and the M1 could not be visualized along its course (grade D, arrow).

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    Fig 2.

    Diagrams showing the ROIs of a 3D stereotaxic ROI template. The white ROIs (precentral, central, parietal, angular, and temporal segments) indicate territories perfused by the bilateral MCAs.

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    Fig 3.

    Comparison of CVR to acetazolamide among the 4 MRA grades in cerebral hemispheres with lesions.

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    Fig 4.

    A 70-year-old man with symptomatic left ICA stenosis (90%) exhibiting MRA grade C (Fig 1). Single-photon emission CT scan shows reduction of resting cerebral blood flow (upper images) and poor acetazolamide-induced increases in perfusion (lower images) in the left MCA territory.

Tables

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  • Concordance rates in interobserver and intraobserver agreements of MRA grading in 108 cerebral hemispheres with lesions

    First Review by First ObserverSecond Review by First ObserverFirst Review by Second Observer
    MRA GradeNumber of HemispheresMRA GradesNumber of HemispheresConcordance Rate in Intraobserver AgreementMRA GradeNumber of HemispheresConcordance Rate in Interobserver Agreement
    A59A591.00A591.00
    B0B0
    C0C0
    D0D0
    B26A00.85A00.85
    B22B22
    C4C4
    D0D0
    C16A00.94A00.88
    B1B1
    C15C14
    D0D1
    D7A01.00A00.71
    B0B0
    C0C2
    D7D5
    • Note:—MRA indicates MR angiography.

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American Journal of Neuroradiology: 30 (3)
American Journal of Neuroradiology
Vol. 30, Issue 3
March 2009
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Simple Assessment of Cerebral Hemodynamics Using Single-Slab 3D Time-of-Flight MR Angiography in Patients with Cervical Internal Carotid Artery Steno-Occlusive Diseases: Comparison with Quantitative Perfusion Single-Photon Emission CT
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R. Hirooka, K. Ogasawara, T. Inoue, S. Fujiwara, M. Sasaki, K. Chida, D. Ishigaki, M. Kobayashi, H. Nishimoto, Y. Otawara, E. Tsushima, A. Ogawa
Simple Assessment of Cerebral Hemodynamics Using Single-Slab 3D Time-of-Flight MR Angiography in Patients with Cervical Internal Carotid Artery Steno-Occlusive Diseases: Comparison with Quantitative Perfusion Single-Photon Emission CT
American Journal of Neuroradiology Mar 2009, 30 (3) 559-563; DOI: 10.3174/ajnr.A1389

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Simple Assessment of Cerebral Hemodynamics Using Single-Slab 3D Time-of-Flight MR Angiography in Patients with Cervical Internal Carotid Artery Steno-Occlusive Diseases: Comparison with Quantitative Perfusion Single-Photon Emission CT
R. Hirooka, K. Ogasawara, T. Inoue, S. Fujiwara, M. Sasaki, K. Chida, D. Ishigaki, M. Kobayashi, H. Nishimoto, Y. Otawara, E. Tsushima, A. Ogawa
American Journal of Neuroradiology Mar 2009, 30 (3) 559-563; DOI: 10.3174/ajnr.A1389
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