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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleBrain
Open Access

The Effect of Exercise on the Cerebral Vasculature of Healthy Aged Subjects as Visualized by MR Angiography

E. Bullitt, F.N. Rahman, J.K. Smith, E. Kim, D. Zeng, L.M. Katz and B.L. Marks
American Journal of Neuroradiology November 2009, 30 (10) 1857-1863; DOI: https://doi.org/10.3174/ajnr.A1695
E. Bullitt
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F.N. Rahman
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J.K. Smith
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E. Kim
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D. Zeng
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L.M. Katz
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B.L. Marks
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    Fig 1.

    A, Axial section of an MRA image. B, Anteroposterior view of a 3D vessel model generated from MRA. Cyan indicates the left middle cerebral circulation; red, the anterior cerebral distribution; blue, the right middle cerebral circulation; gold, the posterior circulation.

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    Fig 2.

    Illustration of abnormal tortuosity. A, Drawing of a healthy intracerebral vessel. The vessel is gently curved. B, Drawing of abnormal tortuosity by SOAM. There are irregular sharp high-frequency low-amplitude curves superimposed on the basic vessel shape. C, Drawing of abnormal tortuosity by ICM. The vessel has elongated and possesses marked C- or S-shaped curves. D, 3D rendering of abnormal SOAM and abnormal ICM values in the same vessel segmented from MRA in 2 different subjects. Left: Healthy vessel. Right: Vessel in a patient with cancer. The vessel possesses abnormal tortuosity by both SOAM and ICM.

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    Fig 3.

    Scatterplots giving vessel-attribute measures in high-activity (light gray) and low-activity (dark gray) subjects. The 3 horizontal lines along each set of scatterplots represent the mean and the mean ± 1 SD. Stars indicate a significant difference (P < .05) between subjects of high and low activity as determined by at least 1 of the statistical measures used. A, Vessel number. B, Average vessel radius (AVR). C, Tortuosity measured by SOAM. D, Tortuosity measured by ICM. H indicates high; L, low; W.H., whole-head circulation; Ant, anterior cerebral circulation; Post, posterior circulation; Left, left middle cerebral circulation; Right, right middle cerebral circulation.

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    Fig 4.

    Comparison of high-activity (light gray) and low-activity (dark gray) groups by the number of vessels of graded radius. Colored bars represent the mean value and vertical lines, the SD. Stars denote statistically significant differences (P < .05) between activity groups. Note that the smallest and largest bins have ranges of >0.1 mm to encompass all vessels. PCA indicates posterior circulation.

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American Journal of Neuroradiology: 30 (10)
American Journal of Neuroradiology
Vol. 30, Issue 10
1 Nov 2009
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E. Bullitt, F.N. Rahman, J.K. Smith, E. Kim, D. Zeng, L.M. Katz, B.L. Marks
The Effect of Exercise on the Cerebral Vasculature of Healthy Aged Subjects as Visualized by MR Angiography
American Journal of Neuroradiology Nov 2009, 30 (10) 1857-1863; DOI: 10.3174/ajnr.A1695

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The Effect of Exercise on the Cerebral Vasculature of Healthy Aged Subjects as Visualized by MR Angiography
E. Bullitt, F.N. Rahman, J.K. Smith, E. Kim, D. Zeng, L.M. Katz, B.L. Marks
American Journal of Neuroradiology Nov 2009, 30 (10) 1857-1863; DOI: 10.3174/ajnr.A1695
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