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Research ArticleBRAIN

Late Evaluation of Silent Cerebral Ischemia Detected by Diffusion-Weighted MR Imaging after Filter-Protected Carotid Artery Stenting

G. Palombo, V. Faraglia, N. Stella, E. Giugni, A. Bozzao and M. Taurino
American Journal of Neuroradiology August 2008, 29 (7) 1340-1343; DOI: https://doi.org/10.3174/ajnr.A1102
G. Palombo
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V. Faraglia
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N. Stella
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E. Giugni
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A. Bozzao
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M. Taurino
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    Fig 1.

    A, Ischemic lesion (arrow) seen on postoperative DWI. B, Delayed MR image in the same patient documents its disappearance.

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    Table 1:

    Baseline characteristics of the 110 patients studied

    CharacteristicsNo. (%)
    Patients110
    Mean age (range) (years)72.6 (56–86)
    Men78 (71)
    Women32 (29)
    Ipsilateral ICA stenosis
        70%–90%106 (96.3)
        >90%4 (3.7)
    Plaque structure
        Type 512 (11)
        Types 3 and 472 (65)
        Types 1 and 226 (24)
    Contralateral ICA stenosis
        0%–50%68 (62)
        50%–69%24 (22)
        70%–99%12 (11)
    Occlusion6 (5)
    Presenting symptoms
        TIA24 (22)
        Stroke6 (5)
    Asymptomatic80 (73)
    Vascular risk factors
        Chronic renal failure5 (4.5)
        Hypertension92 (84)
        Cigarette smoking49 (45)
        Diabetes45 (41)
        Hyperlipidemia60 (55)
        Chronic obstructive pulmonary disease8 (7)
        Coronary artery disease36 (33)
        Peripheral vascular disease17 (15)
    • Note:—TIA indicates transient ischemic attack; ICA, internal carotid artery.

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    Table 2:

    Location of postoperative DWI ischemic lesions and after a mean 6.2-month follow-up

    LocationPostoperative DWIMR Imaging Follow-UpP*
    PersistedDisappearedLost
    Cortical194 (25%)12 (75%)3.02
    Subcortical107 (70%)3 (30%)0
    Deep white matter31 (33%)2 (66%)0
    Basal ganglia101 (100%)0
    Total3312 (40%)18 (60%)3
    • * P value by χ2 test.

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    Table 3:

    Size of postoperative DWI and follow-up MR imaging ischemic lesions

    SizePostoperative DWIFollow-Up MR ImagingP*
    PersistedDisappearedLost
    0–5 mm193 (17%)14 (83%)2.004
    5–10 mm149 (69%)4 (31%)1
    Total3312183
    • * P value by χ2 test.

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    Table 4:

    Analysis of possible factors influencing patient reversibility rate

    FactorsNo. Patients with DWI LesionsNo. Patients with Persistent MR Imaging LesionsP*
    Preoperative microinfarctual brain63 (50%).3
    Normal brain10
    Age ≥80 years33 (100%).1
    Age <80 years105 (50%)
    Types 1 and 2 carotid plaque10.2
    Types 3–5 carotid plaque128 (67%)
    Asymptomatic85 (62%).9
    Symptomatic53 (60%)
    • * P values by χ2 test.

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American Journal of Neuroradiology: 29 (7)
American Journal of Neuroradiology
Vol. 29, Issue 7
August 2008
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Cite this article
G. Palombo, V. Faraglia, N. Stella, E. Giugni, A. Bozzao, M. Taurino
Late Evaluation of Silent Cerebral Ischemia Detected by Diffusion-Weighted MR Imaging after Filter-Protected Carotid Artery Stenting
American Journal of Neuroradiology Aug 2008, 29 (7) 1340-1343; DOI: 10.3174/ajnr.A1102

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Late Evaluation of Silent Cerebral Ischemia Detected by Diffusion-Weighted MR Imaging after Filter-Protected Carotid Artery Stenting
G. Palombo, V. Faraglia, N. Stella, E. Giugni, A. Bozzao, M. Taurino
American Journal of Neuroradiology Aug 2008, 29 (7) 1340-1343; DOI: 10.3174/ajnr.A1102
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  • Carotid Artery Stenting without Angioplasty and Cerebral Protection: A Single-Center Experience with up to 7 Years' Follow-Up
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    Journal of Vascular Surgery 2009 49 2
  • Silent brain infarcts on diffusion-weighted imaging after carotid revascularisation: A surrogate outcome measure for procedural stroke? A systematic review and meta-analysis
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  • A Prospective Evaluation of Cerebral Infarction following Transcervical Carotid Stenting with Carotid Flow Reversal
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    Luis Henrique de Castro-Afonso, Lucas Giansante Abud, Jaicer Gonçalves Rolo, Antônio Carlos dos Santos, Lívia de Oliveira, Clara Monteiro Antunes Barreira, Tonicarlo Rodrigues Velasco, Octávio Marques Pontes-Neto, Daniel Giansante Abud
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