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Research ArticlePediatric Neuroimaging

Long-Term MR Imaging Course of Neurodegenerative Langerhans Cell Histiocytosis

H. Prosch, N. Grois, M. Wnorowski, M. Steiner and D. Prayer
American Journal of Neuroradiology June 2007, 28 (6) 1022-1028; DOI: https://doi.org/10.3174/ajnr.A0509
H. Prosch
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N. Grois
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M. Wnorowski
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M. Steiner
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D. Prayer
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References

  1. ↵
    The French Langerhans’ Cell Histiocytosis Study Group. A multicentre retrospective survey of Langerhans’ cell histiocytosis: 348 cases observed between 1983 and 1993. Arch Dis Child 1996;75:17–24
    Abstract/FREE Full Text
  2. ↵
    Arceci RJ. The histiocytoses: the fall of the Tower of Babel. Eur J Cancer 1999;35:747–67; discussion, 767–69
    CrossRefPubMedWeb of Science
  3. ↵
    Tien RD, Newton TH, McDermott MW, et al. Thickened pituitary stalk on MR images in patients with diabetes insipidus and Langerhans cell histiocytosis. AJNR Am J Neuroradiol 1990;11:703–08
    Abstract/FREE Full Text
  4. Czech T, Mazal PR, Schima W. Resection of a Langerhans cell histiocytosis granuloma of the hypothalamus: case report. Br J Neurosurg 1999;13:196–200
    CrossRefPubMed
  5. ↵
    Grois N, Prayer D, Prosch H, et al. Neuropathology of CNS disease in Langerhans cell histiocytosis. Brain 2005;128:829–38
    Abstract/FREE Full Text
  6. ↵
    Barthez MA, Araujo E, Donadieu J. Langerhans cell histiocytosis and the central nervous system in childhood: evolution and prognostic factors. Results of a collaborative study. J Child Neurol 2000;15:150–56
    Abstract/FREE Full Text
  7. ↵
    Prayer D, Grois N, Prosch H, et al. MR imaging presentation of intracranial disease associated with Langerhans cell histiocytosis. AJNR Am J Neuroradiol 2004;25:880–91
    Abstract/FREE Full Text
  8. ↵
    Grois N, Barkovich AJ, Rosenau W, et al. Central nervous system disease associated with Langerhans’ cell histiocytosis. Am J Pediatr Hematol Oncol 1993;15:245–54
    PubMedWeb of Science
  9. ↵
    Martin-Duverneuil N, Idbaih A, Hoang-Xuan K, et al. MRI features of neurodegenerative Langerhans cell histiocytosis. Eur Radiol 2006;16:2074–82
    CrossRefPubMedWeb of Science
  10. ↵
    Grois NG, Favara BE, Mostbeck GH, et al. Central nervous system disease in Langerhans cell histiocytosis. Hematol Oncol Clin North Am 1998;12:287–305
    CrossRefPubMedWeb of Science
  11. ↵
    Broadbent V, Gadner H, Komp DM, et al. Histiocytosis syndromes in children: II. Approach to the clinical and laboratory evaluation of children with Langerhans cell histiocytosis. Clinical Writing Group of the Histiocyte Society. Med Pediatr Oncol 1989;17:492–95
    CrossRefPubMedWeb of Science
  12. ↵
    Mittheisz E, Seidl R, Prayer D, et al. Central nervous system-related permanent consequences in patients with Langerhans cell histiocytosis. Pediatr Blood Cancer 2007;48:50–56
    CrossRefPubMed
  13. ↵
    Poe LB, Dubowy RL, Hochhauser L, et al. Demyelinating and gliotic cerebellar lesions in Langerhans cell histiocytosis. AJNR Am J Neuroradiol 1994;15:1921–28
    Abstract/FREE Full Text
  14. ↵
    Donadieu J, Rolon MA, Thomas C, et al. Endocrine involvement in pediatric-onset Langerhans’ cell histiocytosis: a population-based study. J Pediatr 2004;144:344–50
    CrossRefPubMed
  15. ↵
    Haupt R, Nanduri V, Calevo MG, et al. Permanent consequences in Langerhans cell histiocytosis patients: a pilot study from the Histiocyte Society-Late Effects Study Group. Pediatr Blood Cancer 2004;42:438–44
    CrossRefPubMedWeb of Science
  16. ↵
    Bohlega S, Alwatban J, Tulbah A, et al. Cerebral manifestation of Erdheim-Chester disease: clinical and radiologic findings. Neurology 1997;49:1702–05
    Abstract/FREE Full Text
  17. Barkhof F, Verrips A, Wesseling P, et al. Cerebrotendinous xanthomatosis: the spectrum of imaging findings and the correlation with neuropathologic findings. Radiology 2000;217:869–76
    PubMedWeb of Science
  18. Su M, Yoshida Y, Hirata Y, et al. Degeneration of the cerebellar dentate nucleus in corticobasal degeneration: neuropathological and morphometric investigations. Acta Neuropathol (Berl) 2000;99:365–70
    CrossRefPubMed
  19. ↵
    Kumada S, Hayashi M, Mizuguchi M, et al. Cerebellar degeneration in hereditary dentatorubral-pallidoluysian atrophy and Machado-Joseph disease. Acta Neuropathol (Berl) 2000;99:48–54
    CrossRefPubMed
  20. ↵
    Klos KJ, Ahlskog JE, Josephs KA, et al. Neurologic spectrum of chronic liver failure and basal ganglia T1 hyperintensity on magnetic resonance imaging: probable manganese neurotoxicity. Arch Neurol 2005;62:1385–90
    CrossRefPubMedWeb of Science
  21. ↵
    Fell JM, Reynolds AP, Meadows N, et al. Manganese toxicity in children receiving long-term parenteral nutrition. Lancet 1996;347:1218–21
    CrossRefPubMedWeb of Science
  22. ↵
    Grois N, Potschger U, Prosch H, et al. Risk factors for diabetes insipidus in Langerhans cell histiocytosis. Pediatr Blood Cancer 2006;46:228–33
    CrossRefPubMed
  23. ↵
    Prosch H, Grois N, Prayer D, et al. Central diabetes insipidus as presenting symptom of Langerhans cell histiocytosis. Pediatr Blood Cancer 2004;43:594–99
    CrossRefPubMed
  24. ↵
    Birnbaum DC, Shields D, Lippe B, et al. Idiopathic central diabetes insipidus followed by progressive spastic cerebral ataxia. Report of four cases. Arch Neurol 1989;46:1001–03
    CrossRefPubMed
  25. ↵
    Goldberg-Stern H, Weitz R, Zaizov R, et al. Progressive spinocerebellar degeneration “plus” associated with Langerhans cell histiocytosis: a new paraneoplastic syndrome? J Neurol Neurosurg Psychiatry 1995;58:180–83
    Abstract/FREE Full Text
  26. ↵
    Bjartmar C, Wujek JR, Trapp BD. Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the disease. J Neurol Sci 2003;206:165–71
    CrossRefPubMedWeb of Science
  27. ↵
    Gadner H, Heitger A, Grois N, et al. Treatment strategy for disseminated Langerhans cell histiocytosis. DAL HX-83 Study Group. Med Pediatr Oncol 1994;23:72–80
    CrossRefPubMedWeb of Science
  28. Ladisch S, Gadner H, Arico M, et al. LCH-I: a randomized trial of etoposide vs. vinblastine in disseminated Langerhans cell histiocytosis. The Histiocyte Society. Med Pediatr Oncol 1994;23:107–10
    PubMedWeb of Science
  29. ↵
    Histiocyte Society. LCH-II: Treatment Protocol of the Second International Study 1996. (unpublished)
  30. ↵
    Polizzi A, Coghill S, McShane MA, et al. Acute ataxia complicating Langerhans cell histiocytosis. Arch Dis Child 2002;86:130–31
    Abstract/FREE Full Text
  31. ↵
    van de Warrenburg BP, van der Heijden HF, Pieters G, et al. Langerhans’ cell histiocytosis presenting with progressive spinocerebellar ataxia. J Neurol 2003;250:1112–14
    CrossRefPubMedWeb of Science
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American Journal of Neuroradiology: 28 (6)
American Journal of Neuroradiology
Vol. 28, Issue 6
June 2007
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Cite this article
H. Prosch, N. Grois, M. Wnorowski, M. Steiner, D. Prayer
Long-Term MR Imaging Course of Neurodegenerative Langerhans Cell Histiocytosis
American Journal of Neuroradiology Jun 2007, 28 (6) 1022-1028; DOI: 10.3174/ajnr.A0509

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Long-Term MR Imaging Course of Neurodegenerative Langerhans Cell Histiocytosis
H. Prosch, N. Grois, M. Wnorowski, M. Steiner, D. Prayer
American Journal of Neuroradiology Jun 2007, 28 (6) 1022-1028; DOI: 10.3174/ajnr.A0509
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  • The spectrum of immune-mediated and inflammatory lesions of the brainstem: Clues to diagnosis
  • T1 Signal Measurements in Pediatric Brain: Findings after Multiple Exposures to Gadobenate Dimeglumine for Imaging of Nonneurologic Disease
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