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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleNeurointervention

Endovascular Treatment of Epistaxis in Patients with Hereditary Hemorrhagic Telangiectasia

K.F. Layton, D.F. Kallmes, L.A. Gray and H.J. Cloft
American Journal of Neuroradiology May 2007, 28 (5) 885-888;
K.F. Layton
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D.F. Kallmes
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L.A. Gray
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H.J. Cloft
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    Fig 1.

    A, Lateral angiogram image after superselective injection of the internal maxillary artery before embolization demonstrates the characteristic patchy mucosal telangiectasias in a patient with HHT.

    B, After embolization with 250–355-μm PVA particles, the abnormal mucosal telangiectasias are no longer visualized.

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    Table 1:

    Comparison of angiographic findings and treatment parameters between patients with HHT and patients with idiopathic epistaxis

    Normal AngiogramRequired Multiple Embolizations
    HHT1/12 (8%)6/12 (50%)
    Idiopathic7/10 (70%)1/10 (10%)
    P = .0062P = 0.0743
    Previous surgery for epistaxis
        HHT8/12 (67%)
        Idiopathic4/10 (40%)
    P = .3913
    Mean number of vessels embolized
        HHT2.75
        Idiopathic2.27
    P = .1975
    Bilateral ECA vessel embolization performed
        HHT15/16 (94%)
        Idiopathic7/11 (64%)
    P = .1252
    • Note:—HHT indicates hereditary hemorrhagic telangiectasia; ECA, external carotid artery. P values were calculated using the Fisher exact test for categoric data and t test for continuous data.

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    Table 2:

    Comparison of embolization efficacy between patients with HHT and those with idiopathic epistaxis

    HHTIdiopathic
    Resolved after 1 embolization3/12 (25%)8/10 (80%)
    Resolved after multiple embolizations3/12 (25%)1/10 (10%)
    Rebleed requiring surgery4/12 (33%)1/10 (10%)
    Significant continued bleeding despite surgery and embolization2/12 (17%)0/10 (0%)
    • Note:—HHT indicates hereditary hemorrhagic telangiectasia.

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American Journal of Neuroradiology: 28 (5)
American Journal of Neuroradiology
Vol. 28, Issue 5
May 2007
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Cite this article
K.F. Layton, D.F. Kallmes, L.A. Gray, H.J. Cloft
Endovascular Treatment of Epistaxis in Patients with Hereditary Hemorrhagic Telangiectasia
American Journal of Neuroradiology May 2007, 28 (5) 885-888;

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Endovascular Treatment of Epistaxis in Patients with Hereditary Hemorrhagic Telangiectasia
K.F. Layton, D.F. Kallmes, L.A. Gray, H.J. Cloft
American Journal of Neuroradiology May 2007, 28 (5) 885-888;
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