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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleSpine Imaging and Spine Image-Guided Interventions

Plasma-Mediated Radiofrequency Ablation Assisted Percutaneous Cement Injection for Treating Advanced Malignant Vertebral Compression Fractures

B.A. Georgy and W. Wong
American Journal of Neuroradiology April 2007, 28 (4) 700-705;
B.A. Georgy
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W. Wong
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  • Fig 1.
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    Fig 1.

    A, Axial CT scans show a large degree of cortical disruption in a 70-year-old man with metastatic colon cancer.

    B and C, The SpineWand device was inserted into the cannula to perform the tissue ablation; the clinician is capable of ablating tissue in a superior or inferior lateral direction.

    D, In this patient, 2 10-mm Kyphon balloons were inserted to obtain hemostasis while preparing the bone cement. A myelogram was performed to clearly delineate the posterior cortical margin.

    E, The axial CT scans collected immediately after the procedure showed that cement was cleanly deposited in the ablated tumor void with no posterior extraosseous extension of cement.

  • Fig 2.
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    Fig 2.

    A, An axial T1-weighted image through the T11 level showing prominent epidural involvement in a 34-year-old woman with multiple myeloma.

    B, The axial CT image showed associated cortical disruption.

    C, The axial CT images obtained after the procedure, showing adequate cement filling with no epidural extension. Note the tight thecal sac as evident by using myelographic contrast agent.

  • Fig 3.
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    Fig 3.

    A, The preprocedure axial CT examination showing almost complete absence of the posterior cortex at the L1 level in a 76-year-old man with metastatic hepatoma to the spine.

    B, The postprocedural CT axial images showed well-bounded deposition of cement in the anterior part of the vertebral body with no extension into the compromised posterior aspect.

Tables

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  • Patient demographics

    PatientAgeSexTreated Level(s)Pathologic ConditionsAnatomy of Metastatic LesionOther ProceduresPain Score (Before–After)Postprocedure CT
    Group 1
        1*75FL2 (Vp)Plasmacytoma, history of breast cancer, lupus erythematosus, chronic steroid usePosterior cortical defectVp, T6, T8, T9, T10 (benign compression fractures)9/10–2/10Cement confined to the lytic lesions
        2*71ML1 (Vp)Lung cancerEpidural extension and posterior cortical defect9/10–3/10Cement confined to the lytic lesions
        327MT11 (Vp)Undifferentiated testicular malignancyEpidural extensionVp, T12, L18/10–5/10, deceasedNo postprocedure CT; no EE on plain film
        4*82ML5 (Vp)Lung squamous cell carcinomaPosterior cortical defect and epidural extension; tumor extension into right neural foramen9/10–5/10Cement on periphery of the metastatic lesion
        552FT9 (Vp)Breast cancerAnterior cortical defectVp, T5, T7, T108/10–5/10Cement around the lytic lesions
        6*70ML2 (Kp)Colon cancerPosterior cortical defect9/10–5/10, deceasedCement confined to the lytic lesions
        7*34FT12 (Kp)Multiple myelomaPosterior cortical defect and epidural extensionKp, T7,T8, T11Cannot tell differenceCement confined to the lytic lesions
        858FT12 (Kp)Breast cancerPosterior cortical disruption and epidural extensionCervical, sacral, and bilateral hip metastases9/10–5/10, deceasedCement confined to the lytic lesions
        980FL4 (Kp)Stomach & breast cancerEpidural extension and complete absence of posterior cortex on CTKp, L2; Vp, L3; followed by Kp, T7, T8, T117/10–3/10Cement confined to the lytic lesions
        1076ML1 (Kp)HepatomaPosterior cortical disruptionKp, L310/10–5/10, deceasedCement confirmed in normal bone anterior to the lytic lesion
        11*72ML1 (Kp)Multiple myelomaEpidural extension; cortical defectVp, L26/10–2/10Cement confined to the lytic lesions
    Group 2
        1256ML1 (Vp)Renal cell metastasisParavertebral extension and lateral cortical disruption2 stage coblation for vertebral & paravertebral components; arterial embolization8/10–2/10Cement confined to the lytic lesions; EE through anterolateral cortex
        1336FL2 (Kp)Cervical cancerAnterior and posterior cortical defect; paraspinal mass extended into left L2–L3 NRBRecurrent lesion after radiation; left L2–L3 NRB9/10–9/10Cement confined to the lytic lesions; some anterior EE
        1466FL3 (Kp right; Vp left)Lung cancerPosterior cortical defect; epidural extension; extension into right neural foramenRight NRB10/10–0/10Cement confined to the lytic lesions; EE anteriorly and into right neural foramen
        1568ML5 (Kp)Urethral cancerEpidural extension and posterior cortical defect; extension into the right pedicle and neural foramenS1 sacroplasty, NRB9/10–7/10Cement on periphery of lesion, extending into the right pedicle
    • Note:—EE indicates extraosseous extension of cement; Group 1, bone cement confined to lytic lesions and confined to vertebral body; Group 2, bone cement with extraosseous extension outside vertebral body; Vp, vertebroplasty; Kp, kyphoplasty; NRB, nerve root block.

    • * Myelogram performed.

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American Journal of Neuroradiology: 28 (4)
American Journal of Neuroradiology
Vol. 28, Issue 4
April 2007
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Cite this article
B.A. Georgy, W. Wong
Plasma-Mediated Radiofrequency Ablation Assisted Percutaneous Cement Injection for Treating Advanced Malignant Vertebral Compression Fractures
American Journal of Neuroradiology Apr 2007, 28 (4) 700-705;

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Plasma-Mediated Radiofrequency Ablation Assisted Percutaneous Cement Injection for Treating Advanced Malignant Vertebral Compression Fractures
B.A. Georgy, W. Wong
American Journal of Neuroradiology Apr 2007, 28 (4) 700-705;
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