Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleBRAIN

Monitoring of Acute Generalized Status Epilepticus Using Multilocal Diffusion MR Imaging: Early Prediction of Regional Neuronal Damage

T. Engelhorn, A. Hufnagel, J. Weise, M. Baehr and A. Doerfler
American Journal of Neuroradiology February 2007, 28 (2) 321-327;
T. Engelhorn
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Hufnagel
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J. Weise
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Baehr
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Doerfler
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Treimann DM, Meyers PD, Walton NY, et al. A comparison of four treatments for generalized convulsive status epilepticus. N Engl J Med 1998;339:792–98
    CrossRefPubMedWeb of Science
  2. ↵
    Lansberg MG, O’Brian MW, Norbash AM, et al. MRI abnormalities associated with partial status epilepticus. Neurology 1999;52:1021–27
    Abstract/FREE Full Text
  3. ↵
    Jack CR, Sharbrough FW, Twomey CK. Temporal lobe seizures: lateralization with MR volume measurements of the hippocampal formation. Radiology 1990;175:423–29
    PubMedWeb of Science
  4. ↵
    Jackson GD, Berkovic SF, Duncan JS, et al. Optimizing the diagnosis of hippocampal sclerosis using MR imaging. AJNR Am J Neuroradiol 1993;14:753–62
    Abstract/FREE Full Text
  5. ↵
    Men S, Lee DH, Barron JR, et al. Selective neuronal necrosis associated with status epilepticus: MR findings. AJNR Am J Neuroradiol 2000;21:1837–40
    Abstract/FREE Full Text
  6. ↵
    Wang Y, Majors A, Jajm I, et al. Postictal alteration of sodium content and apparent diffusion coefficient in epileptic rat brain induced by kainic acid. Epilepsie 1996;37:1000–06
  7. ↵
    Nakasu Y, Nakasu S, Morikawa S, et al. Diffusion-weighted MR in experimental sustained seizures elicited with kainic acid. AJNR Am J Neuroradiol 1995;16:1185–92
    Abstract
  8. ↵
    Wall CJ, Kendall EJ, Obenaus A. Rapid alterations in diffusion-weighted images with anatomic correlates in a rodent model of status epilepticus. AJNR Am J Neuroradiol 2000;21:1841–52
    Abstract/FREE Full Text
  9. El-Koussy M, Mathis J, Lovblad KO, et al. Focal status epilepticus: follow-up by perfusion- and diffusion MRI. Eur Radiol 2002;12:568–74
    PubMedWeb of Science
  10. ↵
    Nairismagi J, Grohn OHJ, Kettunen MI, et al. Progression of brain damage after status epilepticus and its association with epileptogenesis: a quantitative MRI study in a rat model of temporal lobe epilepsy. Epilepsia 2004;45:1024–34
    CrossRefPubMedWeb of Science
  11. ↵
    Obenaus A, Kendall E, Sarty G. Apparent diffusion coefficients following pilocarpine-induced seizures: correlation with anatomical changes. Soc Neurosci Abstr 1998;24:719
  12. ↵
    Engelhorn T, Doerfler A, Weise J, et al. Cerebral perfusion alterations during the acute phase of generalized status epilepticus: prediction of survival using perfusion-weighted magnetic resonance imaging and histopathology. AJNR Am J Neuroradiol 2005;26:1563–70
    Abstract/FREE Full Text
  13. ↵
    Turski L, Cavalheiro EA, Turski WA, et al. Excitatory neurotransmission within substantia nigra pars reticulata regulates threshold for seizures produced by pilocarpine in rats: effects of intranigral 2-amino-7-phosphonoheptanoate and N-methyl-d-aspartate. Neurosci 1986;18:61–77
    CrossRefPubMedWeb of Science
  14. ↵
    Obenaus A, Esclapez M, Houser CR. Loss of glutamate decarboxylase mRNA-containing neurons in the rat of the dentate gyrus following pilocarpine-induced seizures. J Neurosci 1993;13:4470–85
    Abstract
  15. ↵
    Cavalheiro EA, Leite JP, Bortolotto ZA, et al. Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures. Epilepsia 1991;32:778–82
    PubMedWeb of Science
  16. ↵
    Baez LA, Eskridge NK, Schein R. Postnatal development of dopaminergic and cholinergic catalepsy in the rat. Eur J Pharmacol 1976;36:155–62
    CrossRefPubMedWeb of Science
  17. ↵
    Turski WA, Cavalheiro EA, Schwarz M, et al. Limbic seizures produced by pilocarpine in rats: behavioural electroencephalographic and neuropathological study. Behav Brain Res 1983;9:315–35
    CrossRefPubMedWeb of Science
  18. ↵
    Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates, vol4 . Toronto: Academic Press;1998
  19. ↵
    Goodman JH. Experimental models of status epilepticus. In: Peterson SL, Albertson TE. Neuropharmacology Methods in Epilepsy Research. Boca Raton: CRC Press;1998 :95–125
  20. Liu Z, Nagao T, Desjardins GC, et al. Quantitative evaluation of neuronal loss in the dorsal hippocampus in rats with long-term pilocarpine seizures. Epilepsy Res 1994;17:237–47
    CrossRefPubMedWeb of Science
  21. ↵
    Fujikawa DG. The temporal evolution of neuronal damage from pilocarpine-induced status epilepticus. Brain Res 1996;725:11–22
    PubMedWeb of Science
  22. ↵
    Turski L, Ikonomidou C, Turski WA, et al. Review: cholonergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel model of intractable epilepsy. Synapse 1989;3:154–71
    CrossRefPubMedWeb of Science
  23. ↵
    Dudek FE, Obenaus A, Schweitzer JS, et al. Functional significance of hippocampal plasticity in epileptic brain: electrophysiological changes in the dentate granule cells associated with mossy fiber sprouting. Hippocampus 1994;4:259–65
    CrossRefPubMedWeb of Science
  24. ↵
    Pierpaoli C, Righini A, Linfante I, et al. Histopathologic correlates of abnormal water diffusion in cerebral ischemic: diffusion-weighted MR imaging and light and lectron microscopic study. Radiology 1993;189:439–48
    PubMedWeb of Science
  25. ↵
    Van Gelderen P, de Vleeschouwer MH, des Pres D, et al. Water diffusion and acute stroke. Magn Reson Med 1994;31:154–63
    PubMedWeb of Science
  26. ↵
    Duncan R, Patterson J, Roberts R. Ictal regional cerebral blood flow in frontal lobe seizures. Seizure 1997;6:393–401
    CrossRefPubMed
  27. ↵
    Nicholson C, Sykova E. Extracellular space structure revealed by diffusion analysis. Trends Neurosci 1998;21:207–15
    CrossRefPubMedWeb of Science
  28. ↵
    Sykova E. Extracellular space volume and geometry of the rat brain after ischemia and central injury. Adv Neurol 1997;73:121–35
    PubMedWeb of Science
  29. ↵
    Peredery O, Persinger MA, Parker G, et al. Temporal changes in neuronal dropout following inductions of lithium/pilocarpine seizures in the rat. Brain Res 2000;881:9–17
    CrossRefPubMedWeb of Science
  30. ↵
    Roch C, Leroy C, Nehlig A, et al. Magnetic resonance imaging in the study of the lithium-pilocarpine model of temporal lobe epilepsy in adult rats. Epilepsia 2002;43:325–35
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 28 (2)
American Journal of Neuroradiology
Vol. 28, Issue 2
February 2007
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Monitoring of Acute Generalized Status Epilepticus Using Multilocal Diffusion MR Imaging: Early Prediction of Regional Neuronal Damage
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
T. Engelhorn, A. Hufnagel, J. Weise, M. Baehr, A. Doerfler
Monitoring of Acute Generalized Status Epilepticus Using Multilocal Diffusion MR Imaging: Early Prediction of Regional Neuronal Damage
American Journal of Neuroradiology Feb 2007, 28 (2) 321-327;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Monitoring of Acute Generalized Status Epilepticus Using Multilocal Diffusion MR Imaging: Early Prediction of Regional Neuronal Damage
T. Engelhorn, A. Hufnagel, J. Weise, M. Baehr, A. Doerfler
American Journal of Neuroradiology Feb 2007, 28 (2) 321-327;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusion
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Enhanced Subcortical Spreading Depression in Familial Hemiplegic Migraine Type 1 Mutant Mice
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Statin Therapy Does Not Affect the Radiographic and Clinical Profile of Patients with TIA and Minor Stroke
  • Usefulness of Quantitative Susceptibility Mapping for the Diagnosis of Parkinson Disease
  • White Matter Alterations in the Brains of Patients with Active, Remitted, and Cured Cushing Syndrome: A DTI Study
Show more BRAIN

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire