Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatric Neuroimaging

Diffusion Tensor MR Imaging Reveals Persistent White Matter Alteration after Traumatic Brain Injury Experienced during Early Childhood

W. Yuan, S.K. Holland, V.J. Schmithorst, N.C. Walz, K.M. Cecil, B.V. Jones, P. Karunanayaka, L. Michaud and S.L. Wade
American Journal of Neuroradiology November 2007, 28 (10) 1919-1925; DOI: https://doi.org/10.3174/ajnr.A0698
W. Yuan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S.K. Holland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
V.J. Schmithorst
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
N.C. Walz
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
K.M. Cecil
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
B.V. Jones
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P. Karunanayaka
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L. Michaud
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S.L. Wade
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Fay GC, Jaffe KM, Polissar NL, et al. Outcome of pediatric traumatic brain injury at three years: a cohort study. Arch Phys Med Rehabil 1994;75:733–41
    PubMedWeb of Science
  2. Fletcher JM, Ewing-Cobbs L, Miner ME, et al. Behavioral changes after closed head injury in children. J Consult Clin Psychol 1990;58:93–98
    CrossRefPubMedWeb of Science
  3. ↵
    Janusz JA, Kirkwood MW, Yeates KO, et al. Social problem-solving skills in children with traumatic brain injury: long-term outcomes and prediction of social competence. Child Neuropsychol 2002;8:179–94
    PubMed
  4. ↵
    Povlishock JT, Katz DI. Update of neuropathology and neurological recovery after traumatic brain injury. J Head Trauma Rehabil 2005;20:76–94
    PubMedWeb of Science
  5. Shaw K, MacKinnon MA, Raghupathi R, et al. TUNEL-positive staining in white and grey matter after fatal head injury in man. Clin Neuropathol 2001;20:106–12
    PubMed
  6. ↵
    Williams S, Raghupathi R, MacKinnon MA, et al. In situ DNA fragmentation occurs in white matter up to 12 months after head injury in man. Acta Neuropathol (Berl) 2001;102:581–90
    PubMed
  7. ↵
    Anderson VA, Catroppa C, Rosenfeld J, et al. Recovery of memory function following traumatic brain injury in pre-school children. Brain Inj 2000;14:679–92
    CrossRefPubMedWeb of Science
  8. Ewing-Cobbs L, Fletcher JM, Levin HS, et al. Longitudinal neuropsychological outcome in infants and preschoolers with traumatic brain injury. J Int Neuropsychol Soc 1997;3:581–91
    PubMed
  9. Ewing-Cobbs L, Miner ME, Fletcher JM, et al. Intellectual, motor, and language sequelae following closed head injury in infants and preschoolers. J Pediatr Psychol 1989;14:531–47
    Abstract/FREE Full Text
  10. ↵
    Levin HS, Song J, Ewing-Cobbs L, et al. Word fluency in relation to severity of closed head injury, associated frontal brain lesions, and age at injury in children. Neuropsychologia 2001;39:122–31
    CrossRefPubMedWeb of Science
  11. ↵
    Levin HS, Williams DH, Valastro M, et al. Corpus callosal atrophy following closed head injury: detection with magnetic resonance imaging. J Neurosurg 1990;73:77–81
    PubMed
  12. Levin HS, Benavidez DA, Verger-Maestre K, et al. Reduction of corpus callosum growth after severe traumatic brain injury in children. Neurology 2000;54:647–53
    Abstract/FREE Full Text
  13. ↵
    Mendelsohn DB, Levin HS, Harward H, et al. Corpus callosum lesions after closed head injury in children: MRI, clinical features and outcome. Neuroradiology 1992;34:384–88
    CrossRefPubMedWeb of Science
  14. ↵
    Le Bihan D, Mangin JF, Poupon C, et al. Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging 2001;13:534–46
    CrossRefPubMedWeb of Science
  15. Neil J, Miller J, Mukherjee P, et al. Diffusion tensor imaging of normal and injured developing human brain—a technical review. NMR Biomed 2002;15:543–52
    CrossRefPubMedWeb of Science
  16. ↵
    Suzuki Y, Matsuzawa H, Kwee IL, et al. Absolute eigenvalue diffusion tensor analysis for human brain maturation. NMR Biomed 2003;16:257–60
    CrossRefPubMedWeb of Science
  17. Barnea-Goraly N, Menon V, Eckert M, et al. White matter development during childhood and adolescence: a cross-sectional diffusion tensor imaging study. Cereb Cortex 2005;15:1848–54
    Abstract/FREE Full Text
  18. ↵
    Snook L, Paulson LA, Roy D, et al. Diffusion tensor imaging of neurodevelopment in children and young adults. Neuroimage 2005;26:1164–73
    CrossRefPubMedWeb of Science
  19. ↵
    Hermoye L, Saint-Martin C, Cosnard G, et al. Pediatric diffusion tensor imaging: normal database and observation of the white matter maturation in early childhood. Neuroimage 2006;29:493–504
    CrossRefPubMedWeb of Science
  20. ↵
    Arfanakis K, Haughton VM, Carew JD, et al. Diffusion tensor MR imaging in diffuse axonal injury. AJNR Am J Neuroradiol 2002;23:794–802
    Abstract/FREE Full Text
  21. ↵
    Huisman TA, Schwamm LH, Schaefer PW, et al. Diffusion tensor imaging as potential biomarker of white matter injury in diffuse axonal injury. AJNR Am J Neuroradiol 2004;25:370–76
    Abstract/FREE Full Text
  22. ↵
    Inglese M, Makani S, Johnson G, et al. Diffuse axonal injury in mild traumatic brain injury: a diffusion tensor imaging study. J Neurosurg 2005;103:298–303
    CrossRefPubMedWeb of Science
  23. ↵
    Xu J, Vanverg T, Rasmussen I, et al. High-resolution diffusion tensor imaging of males suffering from traumatic brain injury. 12th Annual Meeting of Human Brain Mapping, CD-ROM in Neuroimage (2006),S2140 ; Florence, Italy,2006
  24. ↵
    Ewing-Cobbs L, Hasan KM, Prasad MR, et al. Corpus callosum diffusion anisotropy correlates with neuropsychological outcomes in twins disconcordant for traumatic brain injury. AJNR Am J Neuroradiol 2006;27:879–81
    Abstract/FREE Full Text
  25. ↵
    Jiang H, van Zijl PC, Kim J, et al. DTIStudio: resource program for diffusion tensor computation and fiber bundle tracking. Comput Methods Programs Biomed 2006;81:106–16
    CrossRefPubMedWeb of Science
  26. ↵
    Schmithorst VJ, Wilke M, Dardzinski BJ, et al. Correlation of white matter diffusivity and anisotropy with age during childhood and adolescence: a cross-sectional diffusion-tensor MR imaging study. Radiology 2002;222:212–18
    CrossRefPubMedWeb of Science
  27. ↵
    Schmithorst VJ, Holland SK. Functional MRI evidence for disparate developmental processes underlying intelligence in boys and girls. Neuroimage 2006;31:1366–79
    CrossRefPubMedWeb of Science
  28. ↵
    Talairach J, Tpurnoux P. Co-planar Stereotaxic Atlas of the Human Brain. New York: Thieme Medical;1988
  29. ↵
    Le TH, Mukherjee P, Henry RG, et al. Diffusion tensor imaging with three-dimensional fiber tractography of traumatic axonal shearing injury: an imaging correlate for the posterior callosal “disconnection” syndrome: case report. Neurosurgery 2005;56:189
    PubMedWeb of Science
  30. ↵
    Schmithorst VJ, Difrancesco M, Dardzinski BJ, et al. Sex Differences in White Matter Diffusion Anisotropy in the Normal Pediatric Population; Miami: International Society of Megnetic Resonance in Medicine;2005
  31. ↵
    Hasan KM, Kanabar BP, Santos RM, et al. Diffusion Tensor MRI after Pediatric Brain Injury. Miami: International Society of Magnetic Resonance in Medicine;2004 :1350
  32. ↵
    Wilde EA, Chu Z, Bigler ED, et al. Diffusion tensor imaging in the corpus callosum in children after moderate to severe traumatic brain injury. J Neurotrauma 2006;23:1412–26
    CrossRefPubMedWeb of Science
  33. ↵
    Brett M, Christoff K, Cusack R, et al. Using the Talairach atlas with the MNI template. Neuroimage;2001;13:S85
    CrossRefWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 28 (10)
American Journal of Neuroradiology
Vol. 28, Issue 10
November 2007
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Diffusion Tensor MR Imaging Reveals Persistent White Matter Alteration after Traumatic Brain Injury Experienced during Early Childhood
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
W. Yuan, S.K. Holland, V.J. Schmithorst, N.C. Walz, K.M. Cecil, B.V. Jones, P. Karunanayaka, L. Michaud, S.L. Wade
Diffusion Tensor MR Imaging Reveals Persistent White Matter Alteration after Traumatic Brain Injury Experienced during Early Childhood
American Journal of Neuroradiology Nov 2007, 28 (10) 1919-1925; DOI: 10.3174/ajnr.A0698

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Diffusion Tensor MR Imaging Reveals Persistent White Matter Alteration after Traumatic Brain Injury Experienced during Early Childhood
W. Yuan, S.K. Holland, V.J. Schmithorst, N.C. Walz, K.M. Cecil, B.V. Jones, P. Karunanayaka, L. Michaud, S.L. Wade
American Journal of Neuroradiology Nov 2007, 28 (10) 1919-1925; DOI: 10.3174/ajnr.A0698
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • Conclusion
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • White Matter Disruption in Pediatric Traumatic Brain Injury: Results from ENIGMA Pediatric msTBI
  • Diffusion Measures Indicate Fight Exposure-Related Damage to Cerebral White Matter in Boxers and Mixed Martial Arts Fighters
  • Long-Term White Matter Changes after Severe Traumatic Brain Injury: A 5-Year Prospective Cohort
  • A Decade of DTI in Traumatic Brain Injury: 10 Years and 100 Articles Later
  • Aberrant Diffusion and Geometric Properties in the Left Arcuate Fasciculus of Developmentally Delayed Children: A Diffusion Tensor Imaging Study
  • Voxel-Based Analysis of Diffusion Tensor Imaging in Mild Traumatic Brain Injury in Adolescents
  • Anisotropic Diffusion Properties in Infants with Hydrocephalus: A Diffusion Tensor Imaging Study
  • Evaluation of Delayed Neuronal and Axonal Damage Secondary to Moderate and Severe Traumatic Brain Injury Using Quantitative MR Imaging Techniques
  • Crossref (85)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species
    Bridgette D. Semple, Klas Blomgren, Kayleen Gimlin, Donna M. Ferriero, Linda J. Noble-Haeusslein
    Progress in Neurobiology 2013 106-107
  • A Decade of DTI in Traumatic Brain Injury: 10 Years and 100 Articles Later
    M.B. Hulkower, D.B. Poliak, S.B. Rosenbaum, M.E. Zimmerman, M.L. Lipton
    American Journal of Neuroradiology 2013 34 11
  • Subconcussive Head Impact Exposure and White Matter Tract Changes over a Single Season of Youth Football
    Naeim Bahrami, Dev Sharma, Scott Rosenthal, Elizabeth M. Davenport, Jillian E. Urban, Benjamin Wagner, Youngkyoo Jung, Christopher G. Vaughan, Gerard A. Gioia, Joel D. Stitzel, Christopher T. Whitlow, Joseph A. Maldjian
    Radiology 2016 281 3
  • Voxel-Based Analysis of Diffusion Tensor Imaging in Mild Traumatic Brain Injury in Adolescents
    Z. Chu, E.A. Wilde, J.V. Hunter, S.R. McCauley, E.D. Bigler, M. Troyanskaya, R. Yallampalli, J.M. Chia, H.S. Levin
    American Journal of Neuroradiology 2010 31 2
  • White Matter Fractional Anisotropy Correlates With Speed of Processing and Motor Speed in Young Childhood Cancer Survivors
    Eline J. Aukema, Matthan W.A. Caan, Nienke Oudhuis, Charles B.L.M. Majoie, Frans M. Vos, Liesbeth Reneman, Bob F. Last, Martha A. Grootenhuis, Antoinette Y.N. Schouten-van Meeteren
    International Journal of Radiation Oncology*Biology*Physics 2009 74 3
  • A Systematic Review of Diffusion Tensor Imaging Findings in Sports-Related Concussion
    Andrew Gardner, Frances Kay-Lambkin, Peter Stanwell, James Donnelly, W. Huw Williams, Alexandra Hiles, Peter Schofield, Christopher Levi, Derek K. Jones
    Journal of Neurotrauma 2012 29 16
  • Emerging Imaging Tools for Use with Traumatic Brain Injury Research
    Jill V. Hunter, Elisabeth A. Wilde, Karen A. Tong, Barbara A. Holshouser
    Journal of Neurotrauma 2012 29 4
  • Sex differences in white matter development during adolescence: A DTI study
    Yingying Wang, Chris Adamson, Weihong Yuan, Mekibib Altaye, Akila Rajagopal, Anna W. Byars, Scott K. Holland
    Brain Research 2012 1478
  • Traumatic brain injury and the frontal lobes: What can we gain with diffusion tensor imaging?
    Giuseppe Zappalà, Michel Thiebaut de Schotten, Paul J. Eslinger
    Cortex 2012 48 2
  • CT and MR in non-neonatal hypoxic–ischemic encephalopathy: radiological findings with pathophysiological correlations
    Leonardo Guilhermino Gutierrez, Àlex Rovira, Luiz Antonio Pezzi Portela, Claudia da Costa Leite, Leandro Tavares Lucato
    Neuroradiology 2010 52 11

More in this TOC Section

  • FRACTURE MR in Congenital Vertebral Anomalies
  • Neuroimaging Delineation and Progression of SLSMD
  • fetal brain development of 10 weeks gestation
Show more PEDIATRIC NEUROIMAGING

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire